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Molecular mass spectrometry imaging in biomedical and life science research
J. Pól, M. Strohalm, V. Havlíček, M. Volný
Language English Country Germany
Document type Journal Article, Research Support, Non-U.S. Gov't, Review
NLK
ProQuest Central
from 1997-01-01 to 1 year ago
Medline Complete (EBSCOhost)
from 2000-01-01 to 1 year ago
Nursing & Allied Health Database (ProQuest)
from 1997-01-01 to 1 year ago
Health & Medicine (ProQuest)
from 1997-01-01 to 1 year ago
Public Health Database (ProQuest)
from 1997-01-01 to 1 year ago
- MeSH
- Biological Science Disciplines methods MeSH
- Biomedical Research methods MeSH
- Spectrometry, Mass, Electrospray Ionization instrumentation methods MeSH
- Humans MeSH
- Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization instrumentation methods MeSH
- Spectrometry, Mass, Secondary Ion instrumentation methods MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
This review describes the current state of mass spectrometry imaging (MSI) in life sciences. A brief overview of mass spectrometry principles is presented followed by a thorough introduction to the MSI workflows, principles and areas of application. Three major desorption-ionization techniques used in MSI, namely, secondary ion mass spectrometry (SIMS), matrix-assisted laser desorption ionization (MALDI), and desorption electrospray ionization (DESI) are described, and biomedical and life science imaging applications of each ionization technique are reviewed. A separate section is devoted to data handling and current challenges and future perspectives are briefly discussed at the end.
Department of Chemistry University of Washington Seattle Washington 98195 United States
Institute of Microbiology Academy of Sciences of the Czech Republic Prague
References provided by Crossref.org
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