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Antibody persistence and immune memory 4 years post-vaccination with combined hepatitis A and B vaccine in adults aged over 40 years
R. Chlibek, F. von Sonnenburg, P. Van Damme, J. Smetana, P. Tichy, B. Gunapalaiah, M. Leyssen, JM. Jacquet,
Language English Country United States
Document type Journal Article, Multicenter Study, Randomized Controlled Trial, Research Support, Non-U.S. Gov't
NLK
Open Access Digital Library
from 1994-03-01
Wiley Online Library (archiv)
from 1994-01-01 to 2012-12-31
- MeSH
- Adult MeSH
- Hepatitis A Antibodies blood MeSH
- Hepatitis A prevention & control MeSH
- Hepatitis B Antibodies blood MeSH
- Hepatitis B prevention & control MeSH
- Immunologic Memory MeSH
- Vaccines, Combined immunology MeSH
- Middle Aged MeSH
- Humans MeSH
- Immunization, Secondary MeSH
- Hepatitis A Vaccines administration & dosage immunology MeSH
- Hepatitis B Vaccines administration & dosage immunology MeSH
- Check Tag
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Multicenter Study MeSH
- Research Support, Non-U.S. Gov't MeSH
- Randomized Controlled Trial MeSH
Persistence of immune response was assessed in adults aged >40 years (N = 596) following primary vaccination with combined hepatitis A/B vaccine or concomitant monovalent hepatitis A and B vaccines. Anti-hepatitis A virus antibody responses persisted for at least 4 years regardless of the vaccine used, with anti-hepatitis B surface antibody responses higher and more sustained in subjects who received the combined hepatitis A/B vaccine. Response rates to an additional dose of the same vaccine(s) used for priming were high.
References provided by Crossref.org
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