Detail
Article
Online article
FT
Medvik - BMC
  • Something wrong with this record ?

Airway function tests and vocal cord paralysis in lung transplant recipients

A. Zapletal, G. Kurland, S.R. Boas, B.E. Noyes, P. Greally, A. Faro, J.M. Armitage, D.M. Orenstein

. 1997 ; 23 (2) : 87-94.

Language English Country United States

Persistent link   https://www.medvik.cz/link/bmc13009973

Grant support
IZ2054 MZ0 CEP Register

Maximum expiratory and inspiratory flow-volume (MEFV, MIFV) curves, specific airway conductance (sGaw), and flexible fiberoptic laryngoscopy were examined in 8 pediatric lung transplant recipients with vocal cord paralysis (VCP). Six were heart-lung (H-L) and 2 double-lung (D-L) recipients, 7 had left VCP, and 1 had right VCP. Based on the pulmonary function tests (PFT), 2 subgroups could be distinguished in the 8 recipients with VCP. Group A (5/8 recipients; mean age, 13 +/- 3.4 years; mean height, 144.3 +/- 12.3 cm) had significantly reduced specific airway conductance (sGaw; < 2 SD from predicted) and normal MEF25, MEF50, peak expiratory flow (PEF), forced expiratory volume in 1 second (FEV1), and %FEV1/forced vital capacity (FVC); this pattern suggested variable extrathoracic airway obstruction. PIF was normal in 4/5 and reduced in 1/5 of these recipients. Group B (3/8 recipients with VCP; mean age, 17 +/- 2.4 years; mean height, 156.3 +/- 12.0 cm) had significantly reduced sGaw, MEF25, MEF50, PEF, FEV1, and %FEV1/FVC, implying primarily small airway obstruction. These recipients had bronchiolitis obliterans. The results suggest that a pattern of reduced sGaw and normal MEFs, PEF, FEV1, and PIF should raise the possibility of VCP in patients after lung transplantation. sGaw is more sensitive than PIF and PEF in identifying airway obstruction due to VCP, and should be routinely included in the follow-up evaluation of lung transplant recipients.

Bibliography, etc.

Literatura

000      
00000naa a2200000 a 4500
001      
bmc13009973
003      
CZ-PrNML
005      
20130402101344.0
007      
ta
008      
130314s1997 xxu f 000 0|eng||
009      
AR
035    __
$a (PubMed)9065945
040    __
$a ABA008 $d ABA008 $e AACR2 $b cze
041    0_
$a eng $b eng
044    __
$a xxu
100    1_
$a Zapletal, Alois, $d 1932-2014 $7 jn20000402711 $u Second Department of Pediatrics, Second Medical School, Charles University Hospital Motol, Prague, Czech Republic
245    10
$a Airway function tests and vocal cord paralysis in lung transplant recipients / $c A. Zapletal, G. Kurland, S.R. Boas, B.E. Noyes, P. Greally, A. Faro, J.M. Armitage, D.M. Orenstein
504    __
$a Literatura $b 15
520    9_
$a Maximum expiratory and inspiratory flow-volume (MEFV, MIFV) curves, specific airway conductance (sGaw), and flexible fiberoptic laryngoscopy were examined in 8 pediatric lung transplant recipients with vocal cord paralysis (VCP). Six were heart-lung (H-L) and 2 double-lung (D-L) recipients, 7 had left VCP, and 1 had right VCP. Based on the pulmonary function tests (PFT), 2 subgroups could be distinguished in the 8 recipients with VCP. Group A (5/8 recipients; mean age, 13 +/- 3.4 years; mean height, 144.3 +/- 12.3 cm) had significantly reduced specific airway conductance (sGaw; < 2 SD from predicted) and normal MEF25, MEF50, peak expiratory flow (PEF), forced expiratory volume in 1 second (FEV1), and %FEV1/forced vital capacity (FVC); this pattern suggested variable extrathoracic airway obstruction. PIF was normal in 4/5 and reduced in 1/5 of these recipients. Group B (3/8 recipients with VCP; mean age, 17 +/- 2.4 years; mean height, 156.3 +/- 12.0 cm) had significantly reduced sGaw, MEF25, MEF50, PEF, FEV1, and %FEV1/FVC, implying primarily small airway obstruction. These recipients had bronchiolitis obliterans. The results suggest that a pattern of reduced sGaw and normal MEFs, PEF, FEV1, and PIF should raise the possibility of VCP in patients after lung transplantation. sGaw is more sensitive than PIF and PEF in identifying airway obstruction due to VCP, and should be routinely included in the follow-up evaluation of lung transplant recipients.
590    __
$a bohemika - dle Pubmed
650    02
$a mladiství $7 D000293
650    02
$a dítě $7 D002648
650    02
$a ženské pohlaví $7 D005260
650    02
$a usilovný výdechový objem $7 D005541
650    02
$a lidé $7 D006801
650    02
$a laryngoskopie $7 D007828
650    02
$a transplantace plic $x fyziologie $7 D016040
650    02
$a mužské pohlaví $7 D008297
650    02
$a pooperační komplikace $x etiologie $x patofyziologie $7 D011183
650    02
$a plicní ventilace $7 D012123
650    12
$a respirační funkční testy $7 D012129
650    02
$a ochrnutí hlasivek $x etiologie $x patofyziologie $7 D014826
700    1_
$a Kurland G $u Children's Hospital of Pittsburgh, University of Pittsburgh, School of Medicine, Pennsylvania, USA
700    1_
$a Boas SR
700    1_
$a Noyes BE
700    1_
$a Greally P
700    1_
$a Faro A
700    1_
$a Armitage JM $7 gn_A_00008598
700    1_
$a Orenstein DM
773    0_
$t Pediatric Pulmonology $x 8755-6863 $g Roč. 23, č. 2 (1997), s. 87-94 $p Pediatr Pulmonol $w MED00010405
773    0_
$p Pediatr Pulmonol $g 23(2):87-94, 1997 Feb $x 8755-6863
910    __
$a ABA008 $b B 1819 $y 3 $z 0
990    __
$a 20130314131116 $b ABA008
991    __
$a 20130402101609 $b ABA008
999    __
$a ok $b bmc $g 972831 $s 808234
BAS    __
$a 3
BMC    __
$a 1997 $b 23 $c 2 $d 87-94 $i 8755-6863 $m Pediatric pulmonology $x MED00010405 $n Pediatr Pulmonol
GRA    __
$a IZ2054 $p MZ0
LZP    __
$a 2013-03/dpbo

Find record

Citation metrics

Archiving options