-
Je něco špatně v tomto záznamu ?
Structure, mechanical properties, corrosion behavior and cytotoxicity of biodegradable Mg-X (X=Sn, Ga, In) alloys
J. Kubásek, D. Vojtěch, J. Lipov, T. Ruml,
Jazyk angličtina Země Nizozemsko
Typ dokumentu časopisecké články, práce podpořená grantem
- MeSH
- biokompatibilní materiály chemie farmakologie MeSH
- buněčná smrt účinky léků MeSH
- fotoelektronová spektroskopie MeSH
- koroze MeSH
- kovy farmakologie MeSH
- lidé MeSH
- mechanické jevy účinky léků MeSH
- mikroskopie elektronová rastrovací MeSH
- nádorové buněčné linie MeSH
- pevnost v tahu účinky léků MeSH
- potenciometrie MeSH
- slitiny chemie farmakologie MeSH
- testování materiálů * MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
As-cast Mg-Sn, Mg-Ga and Mg-In alloys containing 1-7 wt.% of alloying elements were studied in this work. Structural and chemical analysis of the alloys was performed by using light and scanning electron microscopy, energy dispersive spectrometry, x-ray diffraction, x-ray photoelectron spectroscopy and glow discharge spectrometry. Mechanical properties were determined by Vickers hardness measurements and tensile testing. Corrosion behavior in a simulated physiological solution (9 g/l NaCl) was studied by immersion tests and potentiodynamic measurements. The cytotoxicity effect of the alloys on human osteosarcoma cells (U-2 OS) was determined by an indirect contact assay. Structural investigation revealed the dendritic morphology of the as-cast alloys with the presence of secondary eutectic phases in the Mg-Sn and Mg-Ga alloys. All the alloying elements showed hardening and strengthening effects on magnesium. This effect was the most pronounced in the case of Ga. All the alloying elements at low concentrations of approximately 1 wt.% were also shown to positively affect the corrosion resistance of Mg. But at higher concentrations of Ga and Sn the corrosion resistance worsened due to galvanic effects of secondary phases. Cytotoxicity tests indicated that Ga had the lowest toxicity, followed by Sn. The most severe toxicity was observed in the case of In.
Citace poskytuje Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc13031537
- 003
- CZ-PrNML
- 005
- 20230414105220.0
- 007
- ta
- 008
- 131002s2013 ne f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.1016/j.msec.2013.02.005 $2 doi
- 035 __
- $a (PubMed)23498278
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a ne
- 100 1_
- $a Kubásek, J $u Department of Metals and Corrosion Engineering, Institute of Chemical Technology, Prague, Technická 5, 166 28 Prague 6, Czech Republic. Jiri.Kubasek@vscht.cz
- 245 10
- $a Structure, mechanical properties, corrosion behavior and cytotoxicity of biodegradable Mg-X (X=Sn, Ga, In) alloys / $c J. Kubásek, D. Vojtěch, J. Lipov, T. Ruml,
- 520 9_
- $a As-cast Mg-Sn, Mg-Ga and Mg-In alloys containing 1-7 wt.% of alloying elements were studied in this work. Structural and chemical analysis of the alloys was performed by using light and scanning electron microscopy, energy dispersive spectrometry, x-ray diffraction, x-ray photoelectron spectroscopy and glow discharge spectrometry. Mechanical properties were determined by Vickers hardness measurements and tensile testing. Corrosion behavior in a simulated physiological solution (9 g/l NaCl) was studied by immersion tests and potentiodynamic measurements. The cytotoxicity effect of the alloys on human osteosarcoma cells (U-2 OS) was determined by an indirect contact assay. Structural investigation revealed the dendritic morphology of the as-cast alloys with the presence of secondary eutectic phases in the Mg-Sn and Mg-Ga alloys. All the alloying elements showed hardening and strengthening effects on magnesium. This effect was the most pronounced in the case of Ga. All the alloying elements at low concentrations of approximately 1 wt.% were also shown to positively affect the corrosion resistance of Mg. But at higher concentrations of Ga and Sn the corrosion resistance worsened due to galvanic effects of secondary phases. Cytotoxicity tests indicated that Ga had the lowest toxicity, followed by Sn. The most severe toxicity was observed in the case of In.
- 650 _2
- $a slitiny $x chemie $x farmakologie $7 D000497
- 650 _2
- $a biokompatibilní materiály $x chemie $x farmakologie $7 D001672
- 650 _2
- $a buněčná smrt $x účinky léků $7 D016923
- 650 _2
- $a nádorové buněčné linie $7 D045744
- 650 _2
- $a koroze $7 D003343
- 650 _2
- $a lidé $7 D006801
- 650 12
- $a testování materiálů $7 D008422
- 650 _2
- $a mechanické jevy $x účinky léků $7 D055595
- 650 _2
- $a kovy $x farmakologie $7 D008670
- 650 _2
- $a mikroskopie elektronová rastrovací $7 D008855
- 650 _2
- $a fotoelektronová spektroskopie $7 D056951
- 650 _2
- $a potenciometrie $7 D011199
- 650 _2
- $a pevnost v tahu $x účinky léků $7 D013718
- 655 _2
- $a časopisecké články $7 D016428
- 655 _2
- $a práce podpořená grantem $7 D013485
- 700 1_
- $a Vojtěch, D $u -
- 700 1_
- $a Lipov, J $u -
- 700 1_
- $a Ruml, T $u -
- 773 0_
- $w MED00184559 $t Materials science & engineering. C, Materials for biological applications $x 0928-4931 $g Roč. 33, č. 4 (2013), s. 2421-32
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/23498278 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y a $z 0
- 990 __
- $a 20131002 $b ABA008
- 991 __
- $a 20230414105213 $b ABA008
- 999 __
- $a ok $b bmc $g 995624 $s 829982
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2013 $b 33 $c 4 $d 2421-32 $i 0928-4931 $m Materials science & engineering. C, Materials for biological applications $n Mater Sci Eng C Mater Biol Appl $x MED00184559
- LZP __
- $a Pubmed-20131002