Šijové prejasnenie je ultrazvukom pozorovateľný znak medzi 10. - 14. týždňom gravidity. Hrúbku nuchálneho prejasnenia nad 95 % percentilom má viac ako 70 % plodov s trizómiou 21. V našej štúdii sme vyšetrili 494 gravidných žien. Ultrasonografické meranie nuchálnej translucencie (NT) sme vykonali medzi 11+3 až 13+6 týždňom gravidity. Minimálna dĺžka embrya bola 45 mm a maximálna 83 mm. Po počítačovom spracovaní bola každej hodnote NT v milimetroch priradená hodnota mediánu (MoM) podľa dĺžky crown-rump length (CRL). Hodnotu vyššiu ako dvojnásobok mediánu sme namerali celkovo 6-krát (1,21 %). V dvoch prípadoch išlo o falošne pozitívny nález. V štyroch prípadoch išlo o patologický nález (1x suspektný Smith-Lemli-Opitz syndróm, 1x Turnerov syndróm, 1x hydrocefalus a 1x defekt komorového septa). Naša štúdia bola prvá na Slovensku, ktorá na reprezentatívnej skupine žien stanovila mediány NT pre neselektovanú slovenskú populáciu.

Nuchal translucence is the sign observed by sonography between 10ts - 14th week of pregnancy. Thickness of nuchal translucence over 95 % of percentil is found in more than 70 % of foetuses with trisonomy 21. In the study 494 pregnant women were examined. Sonographic measuring of nuchal translucence (NT) was performed between 11+3 - 13+6 weeks of gravidity. Minimum length of the embryo was 83 mm. After computer elaborating of data the value of median (MoM) according to crown-rump length (CRL) was added to each NT value in mm. Value two-fold higher than MoM was measured 6 times (1,21 %). In two cases a false positive finding was measured. In 4 cases a pathological finding was recorded (1 suspected Smith-Lemli-Opitz syndrome, 1 Turner syndrome, 1 hydrocephalus and 1 defect of ventricular septum). Our study has been the first study in Slovakia that determined median NT on the representative group of women for non-selected Slovak population.

Nuchal translucence