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Screening for anthelmintic resistance in equid strongyles (Nematoda) in Romania
M. Cernea, R. T. Cristina, L. C. Stefanut, L. M. Madeira de Carvalho, M. A. Taulescu, V. Cozma,
Jazyk angličtina Země Česko
Typ dokumentu práce podpořená grantem, časopisecké články
NLK
Free Medical Journals
od 1966
ProQuest Central
od 2004-01-01 do Před 3 měsíci
Health & Medicine (ProQuest)
od 2004-01-01 do Před 3 měsíci
Public Health Database (ProQuest)
od 2004-01-01 do Před 3 měsíci
ROAD: Directory of Open Access Scholarly Resources
od 1982
- MeSH
- albendazol terapeutické užití MeSH
- Equidae parazitologie MeSH
- feces parazitologie MeSH
- fenbendazol terapeutické užití MeSH
- infekce hlísticemi řádu Strongylida farmakoterapie imunologie MeSH
- ivermektin terapeutické užití MeSH
- léková rezistence * MeSH
- parazitární zátěž MeSH
- statistika jako téma MeSH
- Strongyloidea * imunologie klasifikace MeSH
- výsledek terapie MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Geografické názvy
- Rumunsko MeSH
Resistance to anthelmintic medication of equid strongyles is a worldwide phenomenon and for this reason systematic investigations of resistant parasite populations are necessary. The purpose of the present study was to investigate the presence and distribution of equid strongyles resistant to the anthelmintics used in Romania, as well as the pre-treatment and post-treatment prevalence of species of strongylid nematodes. The Faecal Egg Count Reduction Test was performed between 2010 and 2013 on a total number of 588 horses and 23 donkeys from 26 locations (subgroups). Animals of the first group (I) consisting of subgroups no. 1-11 were treated with Albendazole (ABZ), those of the second group (II) consisting of subgroups no. 12-23 with Fenbendazole (FBZ), while Ivermectin (IVM) was used on animals of the third group (III) consisting of subgroups no. 24-26. Resistant strongyles have been found in 82% (average lower limit of the 95% confidence interval, LCL95%, was 65) of the total equids from the group treated with ABZ. In the group of horses treated with FBZ, resistant strongyles were identified in 75% of the subgroups (LCL95% = 44). No resistant strongyles have been identified in IVM-treated horse groups (LCL95% = 98). The pre-treatment prevalence of the species of the Strongylinae Müller, 1780 was 22%, whereas that with nematodes of the subfamily Cyathostominae Molin, 1861 78%. Post-treatment reduction of strongyline nematodes was observed (5%), which demonstrates the sensitivity of large strongyles to common anthelmintics. The post-treatment prevalence of cyathostomes was of 95%, which proves their resistance, especially to ABZ- and FBZ-based anthelmintics.
Citace poskytuje Crossref.org
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