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Transmission potential of antimony-resistant leishmania field isolates
V. Seblova, B. Oury, N. Eddaikra, K. Aït-Oudhia, F. Pratlong, E. Gazanion, C. Maia, P. Volf, D. Sereno,
Jazyk angličtina Země Spojené státy americké
Typ dokumentu časopisecké články, práce podpořená grantem
Freely Accessible Science Journals od 1995 do Před 6 měsíci
PubMed Central od 1972 do Před 6 měsíci
Europe PubMed Central od 1972 do Před 6 měsíci
Open Access Digital Library od 1972-01-01
Open Access Digital Library od 1972-01-01
Odkazy
PubMed
25049256
DOI
10.1128/aac.02406-13
Knihovny.cz E-zdroje
- MeSH
- antimon farmakologie MeSH
- hmyz - vektory MeSH
- Leishmania infantum patogenita MeSH
- Leishmania patogenita MeSH
- Phlebotomus parazitologie MeSH
- Psychodidae parazitologie MeSH
- zvířata MeSH
- Check Tag
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
We studied the development of antimony-resistant Leishmania infantum in natural vectors Lutzomyia longipalpis and Phlebotomus perniciosus to ascertain the risk of parasite transmission by sand flies. All three resistant strains produced fully mature late-stage infections in sand flies; moreover, the resistant phenotype was maintained after the passage through the vector. These results highlight the risk of circulation of resistant Leishmania strains and question the use of human drugs for treatment of dogs as Leishmania reservoirs.
Centre de Recherche en Infectiologie du CHUL Québec Québec Canada
Department of Parasitology Faculty of Science Charles University Prague Prague Czech Republic
Ecole Nationale Supérieure Vétérinaire d'Alger Hassan Badi El Harrach Alger Algeria
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