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Hyaluronidase Activity in Saliva of European Culicoides (Diptera: Ceratopogonidae)

J. Rádrová, M. Vlková, V. Volfová, P. Sumová, C. Cêtre-Sossah, S. Carpenter, K. Darpel, I. Rakotoarivony, X. Allène, J. Votýpka, P. Volf,

. 2016 ; 53 (1) : 212-6. [pub] 20151019

Jazyk angličtina Země Anglie, Velká Británie

Typ dokumentu časopisecké články, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/bmc16020206
E-zdroje Online Plný text

NLK ProQuest Central od 2016-01-01 do Před 1 rokem
Health & Medicine (ProQuest) od 2016-01-01 do Před 1 rokem
Public Health Database (ProQuest) od 2016-01-01 do Před 1 rokem

Odkazy

PubMed 26487248
DOI 10.1093/jme/tjv147
Knihovny.cz E-zdroje

Biting midges of the genus Culicoides transmit pathogens of veterinary importance such as bluetongue virus (Reoviridae: Orbivirus). The saliva of Culicoides is known to contain bioactive molecules including peptides and proteins with vasodilatory and immunomodulative properties. In this study, we detected activity of enzyme hyaluronidase in six Culicoides species that commonly occur in Europe and that are putative vectors of arboviruses. Hyaluronidase was present in all species studied, although its molecular size, sensitivity to SDS, and substrate specificity differed between species. Further studies on the potential effect of hyaluronidase activity on the vector competence of Culicoides species for arboviruses would be beneficial.

Citace poskytuje Crossref.org

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