• Je něco špatně v tomto záznamu ?

Endogenously produced hydrogen sulfide is involved in porcine oocyte maturation in vitro

J. Nevoral, T. Žalmanová, K. Zámostná, T. Kott, V. Kučerová-Chrpová, JF. Bodart, A. Gelaude, R. Procházka, M. Orsák, M. Šulc, P. Klein, M. Dvořáková, I. Weingartová, A. Víghová, K. Hošková, T. Krejčová, F. Jílek, J. Petr,

. 2015 ; 51 (-) : 24-35. [pub] 20151009

Jazyk angličtina Země Spojené státy americké

Typ dokumentu časopisecké články, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/bmc16028109

Hydrogen sulfide, one of three known gasotransmitters, is involved in physiological processes, including reproductive functions. Oocyte maturation and surrounding cumulus cell expansion play an essential role in female reproduction and subsequent embryonic development. Although the positive effects of exogenous hydrogen sulfide on maturing oocytes are well known, the role of endogenous hydrogen sulfide, which is physiologically released by enzymes, has not yet been described in oocytes. In this study, we observed the presence of Cystathionine β-Synthase (CBS), Cystathionine γ-Lyase (CTH) and 3-Mercaptopyruvate Sulfurtransferase (3-MPST), hydrogen sulfide-releasing enzymes, in porcine oocytes. Endogenous hydrogen sulfide production was detected in immature and matured oocytes as well as its requirement for meiotic maturation. Individual hydrogen sulfide-releasing enzymes seem to be capable of substituting for each other in hydrogen sulfide production. However, meiosis suppression by inhibition of all hydrogen sulfide-releasing enzymes is not irreversible and this effect is a result of M-Phase/Maturation Promoting Factor (MPF) and Mitogen-Activated Protein Kinase (MAPK) activity inhibition. Futhermore, cumulus expansion expressed by hyaluronic acid (HA) production is affected by the inhibition of hydrogen sulfide production. Moreover, quality changes of the expanded cumuli are indicated. These results demonstrate hydrogen sulfide involvement in oocyte maturation as well as cumulus expansion. As such, hydrogen sulfide appears to be an important cell messenger during mammalian oocyte meiosis and adequate cumulus expansion.

000      
00000naa a2200000 a 4500
001      
bmc16028109
003      
CZ-PrNML
005      
20161027122448.0
007      
ta
008      
161005s2015 xxu f 000 0|eng||
009      
AR
024    7_
$a 10.1016/j.niox.2015.09.007 $2 doi
024    7_
$a 10.1016/j.niox.2015.09.007 $2 doi
035    __
$a (PubMed)26456342
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xxu
100    1_
$a Nevoral, Jan $u Czech University of Life Sciences in Prague, Faculty of Agrobiology, Food and Natural Resources, Department of Veterinary Sciences, Prague, Czech Republic. Electronic address: nevoral@af.czu.cz.
245    10
$a Endogenously produced hydrogen sulfide is involved in porcine oocyte maturation in vitro / $c J. Nevoral, T. Žalmanová, K. Zámostná, T. Kott, V. Kučerová-Chrpová, JF. Bodart, A. Gelaude, R. Procházka, M. Orsák, M. Šulc, P. Klein, M. Dvořáková, I. Weingartová, A. Víghová, K. Hošková, T. Krejčová, F. Jílek, J. Petr,
520    9_
$a Hydrogen sulfide, one of three known gasotransmitters, is involved in physiological processes, including reproductive functions. Oocyte maturation and surrounding cumulus cell expansion play an essential role in female reproduction and subsequent embryonic development. Although the positive effects of exogenous hydrogen sulfide on maturing oocytes are well known, the role of endogenous hydrogen sulfide, which is physiologically released by enzymes, has not yet been described in oocytes. In this study, we observed the presence of Cystathionine β-Synthase (CBS), Cystathionine γ-Lyase (CTH) and 3-Mercaptopyruvate Sulfurtransferase (3-MPST), hydrogen sulfide-releasing enzymes, in porcine oocytes. Endogenous hydrogen sulfide production was detected in immature and matured oocytes as well as its requirement for meiotic maturation. Individual hydrogen sulfide-releasing enzymes seem to be capable of substituting for each other in hydrogen sulfide production. However, meiosis suppression by inhibition of all hydrogen sulfide-releasing enzymes is not irreversible and this effect is a result of M-Phase/Maturation Promoting Factor (MPF) and Mitogen-Activated Protein Kinase (MAPK) activity inhibition. Futhermore, cumulus expansion expressed by hyaluronic acid (HA) production is affected by the inhibition of hydrogen sulfide production. Moreover, quality changes of the expanded cumuli are indicated. These results demonstrate hydrogen sulfide involvement in oocyte maturation as well as cumulus expansion. As such, hydrogen sulfide appears to be an important cell messenger during mammalian oocyte meiosis and adequate cumulus expansion.
650    _2
$a zvířata $7 D000818
650    _2
$a western blotting $7 D015153
650    _2
$a ženské pohlaví $7 D005260
650    _2
$a kyselina hyaluronová $x chemie $7 D006820
650    _2
$a sulfan $x metabolismus $7 D006862
650    _2
$a imunohistochemie $7 D007150
650    _2
$a oocyty $x enzymologie $x růst a vývoj $7 D009865
650    _2
$a kvantitativní polymerázová řetězová reakce $7 D060888
650    _2
$a prasata $x růst a vývoj $x fyziologie $7 D013552
655    _2
$a časopisecké články $7 D016428
655    _2
$a práce podpořená grantem $7 D013485
700    1_
$a Žalmanová, Tereza $u Czech University of Life Sciences in Prague, Faculty of Agrobiology, Food and Natural Resources, Department of Veterinary Sciences, Prague, Czech Republic.
700    1_
$a Zámostná, Kateřina $u Czech University of Life Sciences in Prague, Faculty of Agrobiology, Food and Natural Resources, Department of Veterinary Sciences, Prague, Czech Republic.
700    1_
$a Kott, Tomáš $u Research Institute of Animal Production, Prague, Czech Republic.
700    1_
$a Kučerová-Chrpová, Veronika $u Czech University of Life Sciences in Prague, Faculty of Agrobiology, Food and Natural Resources, Department of Veterinary Sciences, Prague, Czech Republic.
700    1_
$a Bodart, Jean-Francois $u Université Lille1, Sciences et Technologies, Team Régulation des Signaux de Division, UMR 8576 CNRS, Villeneuve d'Ascq Cedex, France.
700    1_
$a Gelaude, Armance $u Université Lille1, Sciences et Technologies, Team Régulation des Signaux de Division, UMR 8576 CNRS, Villeneuve d'Ascq Cedex, France.
700    1_
$a Procházka, Radek $u Institute of Animal Physiology and Genetics, Czech Academy of Sciences, Liběchov, Czech Republic.
700    1_
$a Orsák, Matyáš $u Czech University of Life Sciences in Prague, Faculty of Agrobiology, Food and Natural Resources, Department of Chemistry, Prague, Czech Republic.
700    1_
$a Šulc, Miloslav $u Czech University of Life Sciences in Prague, Faculty of Agrobiology, Food and Natural Resources, Department of Chemistry, Prague, Czech Republic.
700    1_
$a Klein, Pavel $u Charles University in Prague, Faculty of Medicine in Pilsen, Biomedical Centre, Pilsen, Czech Republic.
700    1_
$a Dvořáková, Markéta $u Czech University of Life Sciences in Prague, Faculty of Agrobiology, Food and Natural Resources, Department of Veterinary Sciences, Prague, Czech Republic.
700    1_
$a Weingartová, Ivona $u Czech University of Life Sciences in Prague, Faculty of Agrobiology, Food and Natural Resources, Department of Veterinary Sciences, Prague, Czech Republic.
700    1_
$a Víghová, Aurélia $u Czech University of Life Sciences in Prague, Faculty of Agrobiology, Food and Natural Resources, Department of Veterinary Sciences, Prague, Czech Republic.
700    1_
$a Hošková, Kristýna $u Czech University of Life Sciences in Prague, Faculty of Agrobiology, Food and Natural Resources, Department of Veterinary Sciences, Prague, Czech Republic.
700    1_
$a Krejčová, Tereza $u Czech University of Life Sciences in Prague, Faculty of Agrobiology, Food and Natural Resources, Department of Veterinary Sciences, Prague, Czech Republic.
700    1_
$a Jílek, František $u Czech University of Life Sciences in Prague, Faculty of Agrobiology, Food and Natural Resources, Department of Veterinary Sciences, Prague, Czech Republic.
700    1_
$a Petr, Jaroslav $u Research Institute of Animal Production, Prague, Czech Republic.
773    0_
$w MED00004882 $t Nitric oxide biology and chemistry official journal of the Nitric Oxide Society $x 1089-8611 $g Roč. 51, č. - (2015), s. 24-35
856    41
$u https://pubmed.ncbi.nlm.nih.gov/26456342 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y a $z 0
990    __
$a 20161005 $b ABA008
991    __
$a 20161027122904 $b ABA008
999    __
$a ok $b bmc $g 1166423 $s 952739
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2015 $b 51 $c - $d 24-35 $e 20151009 $i 1089-8611 $m Nitric oxide $n Nitric oxide $x MED00004882
LZP    __
$a Pubmed-20161005

Najít záznam

Citační ukazatele

Možnosti archivace