-
Something wrong with this record ?
60,000 years of interactions between Central and Eastern Africa documented by major African mitochondrial haplogroup L2
M. Silva, F. Alshamali, P. Silva, C. Carrilho, F. Mandlate, M. Jesus Trovoada, V. Černý, L. Pereira, P. Soares,
Language English Country England, Great Britain
Document type Historical Article, Journal Article, Research Support, Non-U.S. Gov't
NLK
Directory of Open Access Journals
from 2011
Free Medical Journals
from 2011
Nature Open Access
from 2011-12-01
PubMed Central
from 2011
Europe PubMed Central
from 2011
ProQuest Central
from 2011-01-01
Open Access Digital Library
from 2011-01-01
Open Access Digital Library
from 2011-01-01
Health & Medicine (ProQuest)
from 2011-01-01
ROAD: Directory of Open Access Scholarly Resources
from 2011
Springer Nature OA/Free Journals
from 2011-12-01
PubMed
26211407
DOI
10.1038/srep12526
Knihovny.cz E-resources
- MeSH
- Black People genetics history MeSH
- History, 15th Century MeSH
- History, 16th Century MeSH
- History, 17th Century MeSH
- History, 18th Century MeSH
- History, 19th Century MeSH
- History, 20th Century MeSH
- History, 21st Century MeSH
- History, Medieval MeSH
- Emigration and Immigration history MeSH
- Haplotypes genetics MeSH
- Polymorphism, Single Nucleotide genetics MeSH
- Humans MeSH
- DNA, Mitochondrial genetics history MeSH
- Evolution, Molecular MeSH
- Molecular Sequence Data MeSH
- Base Sequence MeSH
- Check Tag
- History, 15th Century MeSH
- History, 16th Century MeSH
- History, 17th Century MeSH
- History, 18th Century MeSH
- History, 19th Century MeSH
- History, 20th Century MeSH
- History, 21st Century MeSH
- History, Medieval MeSH
- Humans MeSH
- Publication type
- Journal Article MeSH
- Historical Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Geographicals
- Africa, Central MeSH
- Africa, Eastern MeSH
Mitochondrial DNA (mtDNA) haplogroup L2 originated in Western Africa but is nowadays spread across the entire continent. L2 movements were previously postulated to be related to the Bantu expansion, but L2 expansions eastwards probably occurred much earlier. By reconstructing the phylogeny of L2 (44 new complete sequences) we provide insights on the complex net of within-African migrations in the last 60 thousand years (ka). Results show that lineages in Southern Africa cluster with Western/Central African lineages at a recent time scale, whereas, eastern lineages seem to be substantially more ancient. Three moments of expansion from a Central African source are associated to L2: (1) one migration at 70-50 ka into Eastern or Southern Africa, (2) postglacial movements (15-10 ka) into Eastern Africa; and (3) the southward Bantu Expansion in the last 5 ka. The complementary population and L0a phylogeography analyses indicate no strong evidence of mtDNA gene flow between eastern and southern populations during the later movement, suggesting low admixture between Eastern African populations and the Bantu migrants. This implies that, at least in the early stages, the Bantu expansion was mainly a demic diffusion with little incorporation of local populations.
] IPATIMUP 4200 Porto Portugal
] IPATIMUP Departamento de Biologia Universidade do Minho 4710 057 Braga Portugal
References provided by Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc16028347
- 003
- CZ-PrNML
- 005
- 20161005131519.0
- 007
- ta
- 008
- 161005s2015 enk f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.1038/srep12526 $2 doi
- 024 7_
- $a 10.1038/srep12526 $2 doi
- 035 __
- $a (PubMed)26211407
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a enk
- 100 1_
- $a Silva, Marina $u IPATIMUP (Instituto de Patologia e Imunologia Molecular da Universidade do Porto), 4200-465 Porto, Portugal.
- 245 10
- $a 60,000 years of interactions between Central and Eastern Africa documented by major African mitochondrial haplogroup L2 / $c M. Silva, F. Alshamali, P. Silva, C. Carrilho, F. Mandlate, M. Jesus Trovoada, V. Černý, L. Pereira, P. Soares,
- 520 9_
- $a Mitochondrial DNA (mtDNA) haplogroup L2 originated in Western Africa but is nowadays spread across the entire continent. L2 movements were previously postulated to be related to the Bantu expansion, but L2 expansions eastwards probably occurred much earlier. By reconstructing the phylogeny of L2 (44 new complete sequences) we provide insights on the complex net of within-African migrations in the last 60 thousand years (ka). Results show that lineages in Southern Africa cluster with Western/Central African lineages at a recent time scale, whereas, eastern lineages seem to be substantially more ancient. Three moments of expansion from a Central African source are associated to L2: (1) one migration at 70-50 ka into Eastern or Southern Africa, (2) postglacial movements (15-10 ka) into Eastern Africa; and (3) the southward Bantu Expansion in the last 5 ka. The complementary population and L0a phylogeography analyses indicate no strong evidence of mtDNA gene flow between eastern and southern populations during the later movement, suggesting low admixture between Eastern African populations and the Bantu migrants. This implies that, at least in the early stages, the Bantu expansion was mainly a demic diffusion with little incorporation of local populations.
- 650 _2
- $a černoši $x genetika $x dějiny $7 D044383
- 650 _2
- $a sekvence nukleotidů $7 D001483
- 650 _2
- $a mitochondriální DNA $x genetika $x dějiny $7 D004272
- 650 _2
- $a emigrace a imigrace $x dějiny $7 D004641
- 650 _2
- $a molekulární evoluce $7 D019143
- 650 _2
- $a haplotypy $x genetika $7 D006239
- 650 _2
- $a dějiny 15. století $7 D049668
- 650 _2
- $a dějiny 16. století $7 D049669
- 650 _2
- $a dějiny 17. století $7 D049670
- 650 _2
- $a dějiny 18. století $7 D049671
- 650 _2
- $a dějiny 19. století $7 D049672
- 650 _2
- $a dějiny 20. století $7 D049673
- 650 _2
- $a dějiny 21. století $7 D049674
- 650 _2
- $a dějiny středověku $7 D049691
- 650 _2
- $a lidé $7 D006801
- 650 _2
- $a molekulární sekvence - údaje $7 D008969
- 650 _2
- $a jednonukleotidový polymorfismus $x genetika $7 D020641
- 651 _2
- $a střední Afrika $7 D000350
- 651 _2
- $a východní Afrika $7 D000351
- 655 _2
- $a historické články $7 D016456
- 655 _2
- $a časopisecké články $7 D016428
- 655 _2
- $a práce podpořená grantem $7 D013485
- 700 1_
- $a Alshamali, Farida $u 1] IPATIMUP (Instituto de Patologia e Imunologia Molecular da Universidade do Porto), 4200-465 Porto, Portugal [2] General Department of Forensic Sciences &Criminology, Dubai Police GHQ, 1493 Dubai, United Arab Emirates. $7 gn_A_00004843
- 700 1_
- $a Silva, Paula $u 1] IPATIMUP (Instituto de Patologia e Imunologia Molecular da Universidade do Porto), 4200-465 Porto, Portugal [2] Faculdade de Medicina da Universidade do Porto, 4200-319 Porto, Portugal [3] i3S (Instituto de Investigação e Inovação em Saúde, Universidade do Porto), 4200 Porto, Portugal.
- 700 1_
- $a Carrilho, Carla $u 1] Faculdade de Medicina, Universidade Eduardo Mondlane, 257 Maputo, Moçambique [2] Hospital Central de Maputo, 1164 Maputo, Moçambique.
- 700 1_
- $a Mandlate, Flávio $u 1] Faculdade de Medicina, Universidade Eduardo Mondlane, 257 Maputo, Moçambique [2] Departamento de Saúde Mental, Ministério da Saúde, 14 Maputo, Moçambique.
- 700 1_
- $a Jesus Trovoada, Maria $u 1] Instituto Gulbenkian Ciência, 2780-156 Oeiras, Portugal [2] Centro Nacional de Endemias, CP 23, São Tomé e Príncipe.
- 700 1_
- $a Černý, Viktor $u Department of Anthropology and Human Genetics, Faculty of Science, Charles University, 128-43 Prague, Czech Republic.
- 700 1_
- $a Pereira, Luísa $u 1] IPATIMUP (Instituto de Patologia e Imunologia Molecular da Universidade do Porto), 4200-465 Porto, Portugal [2] Faculdade de Medicina da Universidade do Porto, 4200-319 Porto, Portugal [3] i3S (Instituto de Investigação e Inovação em Saúde, Universidade do Porto), 4200 Porto, Portugal.
- 700 1_
- $a Soares, Pedro $u 1] IPATIMUP (Instituto de Patologia e Imunologia Molecular da Universidade do Porto), 4200-465 Porto, Portugal [2] CBMA (Centro de Biologia Molecular e Ambiental), Departamento de Biologia, Universidade do Minho, 4710-057 Braga, Portugal.
- 773 0_
- $w MED00182195 $t Scientific reports $x 2045-2322 $g Roč. 5, č. - (2015), s. 12526
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/26211407 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y a $z 0
- 990 __
- $a 20161005 $b ABA008
- 991 __
- $a 20161005131906 $b ABA008
- 999 __
- $a ok $b bmc $g 1166661 $s 952977
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2015 $b 5 $c - $d 12526 $e 20150727 $i 2045-2322 $m Scientific reports $n Sci Rep $x MED00182195
- LZP __
- $a Pubmed-20161005
