• Je něco špatně v tomto záznamu ?

Neck Muscles and Content of Carotid Artery as Reference Tissue for Strain Ratio - a Novel Approach to Improve the Diagnostic Performance of Thyroid Elastography

J. Kratky, H. Vitkova, J. Bartakova, J. Lukas, J. Jiskra,

. 2016 ; 124 (3) : 192-7. [pub] 20160323

Jazyk angličtina Země Německo

Typ dokumentu časopisecké články, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/bmc17000321

Measurement of thyroid nodule stiffness by strain elastography already showed promising results. The aim of our study was to evaluate the diagnostic performance of elastography in predicting thyroid cancer by determination of strain ratio comparing nodule stiffness with thyroid tissue and surrounding neck tissues as well (carotid artery, neck muscles). Totally, 310 thyroid nodules in 275 patients were examined by conventional ultrasound and elastography prior to aspiration biopsy. 22(7.1%) thyroid carcinomas were histologically confirmed and included in the study. 39 benign nodules (27 confirmed by histology and 12 with benign cytology and at least 2 years stable ultrasound finding) formed control group. Elastography was evaluated qualitatively using 6-grade score and strain ratio to surrounding thyroid tissue, carotid artery and neck muscles was determined. High-risk elastographic score (4,5) was more frequent in carcinomas (67%) compared with benign nodules (11%, p<0.001). Significant differences in distribution of strain were found in all studied parameters except comparison with thyroid tissue in transversal dimension. Strain ratio comparing the stiffness with neck muscles had a higher negative predictive value than elastographic score and conventional ultrasound (92 vs. 83 and 82% respectively). Moreover, the combination of ultrasound and strain ratio to neck muscles increased sensitivity and negative predictive value to 100%. Our results suggest, that strain ratio to neck muscles in combination with ultrasound seems to have good sensitivity and negative predictive value for predicting thyroid cancer and may be beneficial in cases when comparison to surrounding thyroid tissue is problematic (Hashimoto thyroiditis, multinodular goiter, large nodule).

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc17000321
003      
CZ-PrNML
005      
20170113115505.0
007      
ta
008      
170103s2016 gw f 000 0|eng||
009      
AR
024    7_
$a 10.1055/s-0035-1569359 $2 doi
024    7_
$a 10.1055/s-0035-1569359 $2 doi
035    __
$a (PubMed)27008636
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a gw
100    1_
$a Kratky, J $u Third Department of Medicine, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague.
245    10
$a Neck Muscles and Content of Carotid Artery as Reference Tissue for Strain Ratio - a Novel Approach to Improve the Diagnostic Performance of Thyroid Elastography / $c J. Kratky, H. Vitkova, J. Bartakova, J. Lukas, J. Jiskra,
520    9_
$a Measurement of thyroid nodule stiffness by strain elastography already showed promising results. The aim of our study was to evaluate the diagnostic performance of elastography in predicting thyroid cancer by determination of strain ratio comparing nodule stiffness with thyroid tissue and surrounding neck tissues as well (carotid artery, neck muscles). Totally, 310 thyroid nodules in 275 patients were examined by conventional ultrasound and elastography prior to aspiration biopsy. 22(7.1%) thyroid carcinomas were histologically confirmed and included in the study. 39 benign nodules (27 confirmed by histology and 12 with benign cytology and at least 2 years stable ultrasound finding) formed control group. Elastography was evaluated qualitatively using 6-grade score and strain ratio to surrounding thyroid tissue, carotid artery and neck muscles was determined. High-risk elastographic score (4,5) was more frequent in carcinomas (67%) compared with benign nodules (11%, p<0.001). Significant differences in distribution of strain were found in all studied parameters except comparison with thyroid tissue in transversal dimension. Strain ratio comparing the stiffness with neck muscles had a higher negative predictive value than elastographic score and conventional ultrasound (92 vs. 83 and 82% respectively). Moreover, the combination of ultrasound and strain ratio to neck muscles increased sensitivity and negative predictive value to 100%. Our results suggest, that strain ratio to neck muscles in combination with ultrasound seems to have good sensitivity and negative predictive value for predicting thyroid cancer and may be beneficial in cases when comparison to surrounding thyroid tissue is problematic (Hashimoto thyroiditis, multinodular goiter, large nodule).
650    _2
$a dospělí $7 D000328
650    _2
$a senioři $7 D000368
650    12
$a arteriae carotides $x patofyziologie $7 D002339
650    12
$a elastografie $7 D054459
650    _2
$a ženské pohlaví $7 D005260
650    _2
$a lidé $7 D006801
650    _2
$a mužské pohlaví $7 D008297
650    _2
$a lidé středního věku $7 D008875
650    12
$a krční svaly $x patofyziologie $7 D009334
650    12
$a štítná žláza $x patofyziologie $7 D013961
650    12
$a uzly štítné žlázy $x patofyziologie $7 D016606
655    _2
$a časopisecké články $7 D016428
655    _2
$a práce podpořená grantem $7 D013485
700    1_
$a Vitkova, H $u Third Department of Medicine, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague.
700    1_
$a Bartakova, J $u Third Department of Medicine, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague.
700    1_
$a Lukas, J $u Department of Otolaryngology - Head and Neck Surgery, Na Homolce Hospital, Prague, and Department of Otolaryngology, Faculty of Medicine, Charles University, Pilsen, Czech Republic.
700    1_
$a Jiskra, J $u Third Department of Medicine, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague.
773    0_
$w MED00009707 $t Experimental and clinical endocrinology & diabetes official journal, German Society of Endocrinology [and] German Diabetes Association $x 1439-3646 $g Roč. 124, č. 3 (2016), s. 192-7
856    41
$u https://pubmed.ncbi.nlm.nih.gov/27008636 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y a $z 0
990    __
$a 20170103 $b ABA008
991    __
$a 20170113115606 $b ABA008
999    __
$a ok $b bmc $g 1179461 $s 960888
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2016 $b 124 $c 3 $d 192-7 $e 20160323 $i 1439-3646 $m Experimental and clinical endocrinology & diabetes $n Exp Clin Endocrinol Diabetes $x MED00009707
LZP    __
$a Pubmed-20170103

Najít záznam

Citační ukazatele

Možnosti archivace