Detail
Article
Online article
FT
Medvik - BMC
  • Something wrong with this record ?

Hemodynamic changes in a middle cerebral artery aneurysm at follow-up times before and after its rupture: a case report and a review of the literature

A. Sejkorová, KD. Dennis, H. Švihlová, O. Petr, G. Lanzino, A. Hejčl, D. Dragomir-Daescu,

. 2017 ; 40 (2) : 329-338. [pub] 20161124

Language English Country Germany

Document type Case Reports, Journal Article, Review

Persistent link   https://www.medvik.cz/link/bmc17023482

Hemodynamic parameters play a significant role in the development of cerebral aneurysms. Parameters such as wall shear stress (WSS) or velocity could change in time and may contribute to aneurysm growth and rupture. However, the hemodynamic changes at the rupture location remain unclear because it is difficult to obtain data prior to rupture. We analyzed a case of a ruptured middle cerebral artery (MCA) aneurysm for which we acquired imaging data at three time points, including at rupture. A patient with an observed MCA aneurysm was admitted to the emergency department with clinical symptoms of a subarachnoid hemorrhage. During three-dimensional (3D) digital subtraction angiography (DSA), the aneurysm ruptured again. Imaging data from two visits before rupture and this 3D DSA images at the moment of rupture were acquired, and computational fluid dynamic (CFD) simulations were performed. Results were used to describe the time-dependent changes of the hemodynamic variables associated with rupture. Time-dependent hemodynamic changes at the rupture location were characterized by decreased WSS and flow velocity magnitude. The impingement jet in the dome changed its position in time and the impingement area at follow-up moved near the rupture location. The results suggest that the increased WSS on the dome and increased low wall shear stress area (LSA) and decreased WSS on the daughter bleb with slower flow and slow vortex may be associated with rupture. CFD performed during the follow-up period may be part of diagnostic tools used to determine the risk of aneurysm rupture.

References provided by Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc17023482
003      
CZ-PrNML
005      
20181029080510.0
007      
ta
008      
170720s2017 gw f 000 0|eng||
009      
AR
024    7_
$a 10.1007/s10143-016-0795-7 $2 doi
035    __
$a (PubMed)27882440
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a gw
100    1_
$a Sejkorová, Alena $u Department of Neurosurgery, Masaryk Hospital, J. E. Purkyně University, Ústí nad Labem, Czech Republic. Division of Engineering, Mayo Clinic, Rochester, MN, USA. $7 xx0228520
245    10
$a Hemodynamic changes in a middle cerebral artery aneurysm at follow-up times before and after its rupture: a case report and a review of the literature / $c A. Sejkorová, KD. Dennis, H. Švihlová, O. Petr, G. Lanzino, A. Hejčl, D. Dragomir-Daescu,
520    9_
$a Hemodynamic parameters play a significant role in the development of cerebral aneurysms. Parameters such as wall shear stress (WSS) or velocity could change in time and may contribute to aneurysm growth and rupture. However, the hemodynamic changes at the rupture location remain unclear because it is difficult to obtain data prior to rupture. We analyzed a case of a ruptured middle cerebral artery (MCA) aneurysm for which we acquired imaging data at three time points, including at rupture. A patient with an observed MCA aneurysm was admitted to the emergency department with clinical symptoms of a subarachnoid hemorrhage. During three-dimensional (3D) digital subtraction angiography (DSA), the aneurysm ruptured again. Imaging data from two visits before rupture and this 3D DSA images at the moment of rupture were acquired, and computational fluid dynamic (CFD) simulations were performed. Results were used to describe the time-dependent changes of the hemodynamic variables associated with rupture. Time-dependent hemodynamic changes at the rupture location were characterized by decreased WSS and flow velocity magnitude. The impingement jet in the dome changed its position in time and the impingement area at follow-up moved near the rupture location. The results suggest that the increased WSS on the dome and increased low wall shear stress area (LSA) and decreased WSS on the daughter bleb with slower flow and slow vortex may be associated with rupture. CFD performed during the follow-up period may be part of diagnostic tools used to determine the risk of aneurysm rupture.
650    _2
$a prasklé aneurysma $x komplikace $x diagnostické zobrazování $x patofyziologie $7 D017542
650    _2
$a digitální subtrakční angiografie $7 D015901
650    _2
$a ženské pohlaví $7 D005260
650    _2
$a hemodynamika $7 D006439
650    _2
$a lidé $7 D006801
650    _2
$a zobrazování trojrozměrné $7 D021621
650    _2
$a intrakraniální aneurysma $x komplikace $x diagnostické zobrazování $x patofyziologie $7 D002532
650    _2
$a lidé středního věku $7 D008875
650    _2
$a modely kardiovaskulární $7 D008955
650    _2
$a subarachnoidální krvácení $x diagnostické zobrazování $x etiologie $7 D013345
655    _2
$a kazuistiky $7 D002363
655    _2
$a časopisecké články $7 D016428
655    _2
$a přehledy $7 D016454
700    1_
$a Dennis, K D $u Division of Engineering, Mayo Clinic, Rochester, MN, USA.
700    1_
$a Švihlová, Helena $7 xx0228511 $u Mathematical Institute of Charles University, 8, Praha, Czech Republic.
700    1_
$a Petr, O $u Department of Neurosurgery, Medical University Innsbruck, Innsbruck, Austria.
700    1_
$a Lanzino, G $u Department of Neurological Surgery, Mayo Clinic, Rochester, MN, USA.
700    1_
$a Hejčl, A $u Department of Neurosurgery, Masaryk Hospital, J. E. Purkyně University, Ústí nad Labem, Czech Republic. International Clinical Research Center, St. Anne's University Hospital, Brno, Czech Republic.
700    1_
$a Dragomir-Daescu, D $u Department of Physiology and Biomedical Engineering, Mayo Clinic, 200 1st St SW, Rochester, MN, 55905, USA. DragomirDaescu.Dan@mayo.edu.
773    0_
$w MED00003513 $t Neurosurgical review $x 1437-2320 $g Roč. 40, č. 2 (2017), s. 329-338
856    41
$u https://pubmed.ncbi.nlm.nih.gov/27882440 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y a $z 0
990    __
$a 20170720 $b ABA008
991    __
$a 20181029081025 $b ABA008
999    __
$a ok $b bmc $g 1239163 $s 984395
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2017 $b 40 $c 2 $d 329-338 $e 20161124 $i 1437-2320 $m Neurosurgical review $n Neurosurg Rev $x MED00003513
LZP    __
$a Pubmed-20170720

Find record

Citation metrics

Logged in users only

Archiving options