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Molecular basis of spermatogenesis and sperm quality

V. Robles, P. Herráez, C. Labbé, E. Cabrita, M. Pšenička, DG. Valcarce, MF. Riesco,

. 2017 ; 245 (-) : 5-9. [pub] 20160427

Jazyk angličtina Země Spojené státy americké

Typ dokumentu časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/bmc17031765

Spermatozoan quality can be evaluated in different ways, here we focus on the analysis of DNA, RNA and epigenetic status of germ cells. These characterizations also can be the bases for explaining sperm quality at other levels, so we will see how some of these molecules could affect other sperm quality markers. Moreover, we consider the possibility of using some of these molecules as predictors of sperm quality in terms of the ability to produce healthy offspring. The relevant effect of different types of RNA molecules in germ line specification and spermatogenesis and the importance of germ cell DNA integrity and a proper epigenetic pattern will be also discussed. Although most studies at this level have been performed in mammals, some information is available for fish; these recent discoveries in fish models are included. We provide a general overview on how these molecules could have a deep influence in the final sperm quality.

Citace poskytuje Crossref.org

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$a Herráez, Paz $u INDEGSAL, University of León, León, Spain; Department of Molecular Biology, University of León, León, Spain.
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$a Labbé, Catherine $u INRA, Fish Physiology and Genomics, Campus de Beaulieu, Rennes, France.
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$a Cabrita, Elsa $u CCMAR-Centre of Marine Sciences, University of Algarve, Portugal.
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$a Valcarce, David G $u INDEGSAL, University of León, León, Spain; Department of Molecular Biology, University of León, León, Spain.
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