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Validation of the EULAR/ERA-EDTA recommendations for the management of ANCA-associated vasculitis by disease content experts

M. Yates, R. Watts, I. Bajema, M. Cid, B. Crestani, T. Hauser, B. Hellmich, J. Holle, M. Laudien, MA. Little, RA. Luqmani, A. Mahr, P. Merkel, J. Mills, J. Mooney, M. Segelmark, V. Tesar, KWA. Westman, A. Vaglio, N. Yalçındağ, DR. Jayne, C. Mukhtyar,

. 2017 ; 3 (1) : e000449. [pub] 20170615

Jazyk angličtina Země Anglie, Velká Británie

Typ dokumentu časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/bmc17031915

The European League Against Rheumatism recommendations for the management of antineutrophil cytoplasmic antibody-associated vasculitis have been recently published. Unique to recommendation development, they were also voted on by members of a learned society. This paper explores the wider validity of the recommendations among people who self-identify as clinicians caring for patients with vasculitis. In addition to the task force, a learned society (European Vasculitis Society-EUVAS) was invited, through online survey, to rate independently the strength of evidence of each recommendation to obtain an indication of the agreement among the final target audience and ultimate end-users of the recommendations. The survey took place in June 2015. Of the 158 EUVAS members surveyed, there were 88 responses (55.7%). There was a large degree of agreement in the voting patterns between EUVAS survey participants and task force members. Notable exceptions were lower grades for the recommendation of the use of rituximab for remission induction in patients with eosinophilic granulomatosis with polyangiitis and for methotrexate and mycophenolate mofetil as remission maintenance agents in patients with granulomatosis with polyangiitis/microscopic polyangiitis by EUVAS members. These results are encouraging and suggest that the voting patterns of the task force are representative of the wider vasculitis community. We recommend future recommendations adopt this approach for data/expert-based treatment guidelines, especially for multisystem diseases.

Assistance Publique Hôpitaux de Paris Department of Pulmonology Bichat Claude Bernard University Hospital Paris France

Department of Internal Medicine Hôpital Saint Louis Université Paris 7 René Diderot Paris France

Department of Medical and Health Sciences Nephrology Linköping University Linköping Sweden

Department of Nephrology 1st Faculty of Medicine Charles University Prague Czech Republic

Department of Nephrology Lund University Skåne University Hospital Lund and Malmö Sweden

Department of Ophthalmology School of Medicine Ankara University Ankara Turkey

Department of Otorhinolaryngology Head and Neck Surgery University of Kiel Kiel Germany

Department of Pathology Leiden University Medical Center Leiden The Netherlands

Department of Rheumatology Norfolk and Norwich University Hospital Norwich UK

Department of Rheumatology Norfolk and Norwich University Hospital Norwich UK Norwich Medical School Bob Champion Research and Education Building Colney Lane Norwich UK

Division of Rheumatology and the Department of Biostatistics and Epidemiology University of Pennsylvania Philadelphia Pennsylvania USA

Immunologie Zentrum Zürich Zürich Switzerland

Lupus and Vasculitis Unit Addenbrooke's Hospital Cambridge UK

Nephrology Unit University Hospital of Parma Parma Italy

Norwich Medical School Bob Champion Research and Education Building Colney Lane Norwich UK Department of Rheumatology Ipswich Hospital NHS Trust Norwich Medical School Norwich UK

Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences Botnar Research Centre University of Oxford Oxford UK

Rheumazentrum Schleswig Holstein Mitte Kuhberg 5a 7 Neumünster Germany

Trinity Health Kidney Centre Tallaght Hospital Dublin Ireland

Vasculitis Research Unit Department of Autoimmune Diseases Hospital Clinic University of Barcelona Institut d'Investigacions Biomèdiques August Pi i Sunyer Barcelona Spain

Vasculitis UK West Bank House Winster Matlock UK

Vaskulits Zentrum Süd Klinik für Innere Medizin Rheumatologie und Immunologie Medius Klinik Kirchheim Kirchheim Teck Germany

Citace poskytuje Crossref.org

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