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Validation of the EULAR/ERA-EDTA recommendations for the management of ANCA-associated vasculitis by disease content experts
M. Yates, R. Watts, I. Bajema, M. Cid, B. Crestani, T. Hauser, B. Hellmich, J. Holle, M. Laudien, MA. Little, RA. Luqmani, A. Mahr, P. Merkel, J. Mills, J. Mooney, M. Segelmark, V. Tesar, KWA. Westman, A. Vaglio, N. Yalçındağ, DR. Jayne, C. Mukhtyar,
Jazyk angličtina Země Anglie, Velká Británie
Typ dokumentu časopisecké články
Free Medical Journals od 2015
PubMed Central od 2015
Europe PubMed Central od 2015
ProQuest Central od 2015-01-01
Open Access Digital Library od 2015-01-01
Open Access Digital Library od 2015-01-01
Health & Medicine (ProQuest) od 2015-01-01
ROAD: Directory of Open Access Scholarly Resources od 2015
Odkazy
PubMed
28955487
DOI
10.1136/rmdopen-2017-000449
Knihovny.cz E-zdroje
- Publikační typ
- časopisecké články MeSH
The European League Against Rheumatism recommendations for the management of antineutrophil cytoplasmic antibody-associated vasculitis have been recently published. Unique to recommendation development, they were also voted on by members of a learned society. This paper explores the wider validity of the recommendations among people who self-identify as clinicians caring for patients with vasculitis. In addition to the task force, a learned society (European Vasculitis Society-EUVAS) was invited, through online survey, to rate independently the strength of evidence of each recommendation to obtain an indication of the agreement among the final target audience and ultimate end-users of the recommendations. The survey took place in June 2015. Of the 158 EUVAS members surveyed, there were 88 responses (55.7%). There was a large degree of agreement in the voting patterns between EUVAS survey participants and task force members. Notable exceptions were lower grades for the recommendation of the use of rituximab for remission induction in patients with eosinophilic granulomatosis with polyangiitis and for methotrexate and mycophenolate mofetil as remission maintenance agents in patients with granulomatosis with polyangiitis/microscopic polyangiitis by EUVAS members. These results are encouraging and suggest that the voting patterns of the task force are representative of the wider vasculitis community. We recommend future recommendations adopt this approach for data/expert-based treatment guidelines, especially for multisystem diseases.
Department of Internal Medicine Hôpital Saint Louis Université Paris 7 René Diderot Paris France
Department of Medical and Health Sciences Nephrology Linköping University Linköping Sweden
Department of Nephrology 1st Faculty of Medicine Charles University Prague Czech Republic
Department of Nephrology Lund University Skåne University Hospital Lund and Malmö Sweden
Department of Ophthalmology School of Medicine Ankara University Ankara Turkey
Department of Otorhinolaryngology Head and Neck Surgery University of Kiel Kiel Germany
Department of Pathology Leiden University Medical Center Leiden The Netherlands
Department of Rheumatology Norfolk and Norwich University Hospital Norwich UK
Immunologie Zentrum Zürich Zürich Switzerland
Lupus and Vasculitis Unit Addenbrooke's Hospital Cambridge UK
Nephrology Unit University Hospital of Parma Parma Italy
Rheumazentrum Schleswig Holstein Mitte Kuhberg 5a 7 Neumünster Germany
Trinity Health Kidney Centre Tallaght Hospital Dublin Ireland
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