-
Je něco špatně v tomto záznamu ?
Progress and Remaining Challenges in the Application of High Frequency Oscillations as Biomarkers of Epileptic Brain
F. Khadjevand, J. Cimbalnik, GA. Worrell,
Jazyk angličtina Země Velká Británie
Typ dokumentu časopisecké články
- Publikační typ
- časopisecké články MeSH
High-frequency oscillations (HFOs: 100 - 600 Hz) have been widely proposed as biomarkers of epileptic brain tissue. In addition, HFOs over a broader range of frequencies spanning 30 - 2000 Hz are potential biomarkers of both physiological and pathological brain processes. The majority of the results from humans with focal epilepsy have focused on HFOs recorded directly from the brain with intracranial EEG (iEEG) in the high gamma (65 - 100 Hz), ripple (100 - 250 Hz), and fast ripple (250 - 600 Hz) frequency ranges. These results are supplemented by reports of HFOs recorded with iEEG in the low gamma (30 - 65Hz) and very high frequency (500 - 2000 Hz) ranges. Visual detection of HFOs is laborious and limited by poor inter-rater agreement; and the need for accurate, reproducible automated HFOs detection is well recognized. In particular, the clinical translation of HFOs as a biomarker of the epileptogenic brain has been limited by the ability to reliably detect and accurately classify HFOs as physiological or pathological. Despite these challenges, there has been significant progress in the field, which is the subject of this review. Furthermore, we provide data and corresponding analytic code in an effort to promote reproducible research and accelerate clinical translation.
Citace poskytuje Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc18009941
- 003
- CZ-PrNML
- 005
- 20210121105948.0
- 007
- ta
- 008
- 180404s2017 xxk f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.1016/j.cobme.2017.09.006 $2 doi
- 035 __
- $a (PubMed)29532041
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a xxk
- 100 1_
- $a Khadjevand, Fatemeh $u Mayo Systems Electrophysiology Laboratory, Department of Neurology, Mayo Clinic, 200 First St SW, Rochester MN, 55905, USA.
- 245 10
- $a Progress and Remaining Challenges in the Application of High Frequency Oscillations as Biomarkers of Epileptic Brain / $c F. Khadjevand, J. Cimbalnik, GA. Worrell,
- 520 9_
- $a High-frequency oscillations (HFOs: 100 - 600 Hz) have been widely proposed as biomarkers of epileptic brain tissue. In addition, HFOs over a broader range of frequencies spanning 30 - 2000 Hz are potential biomarkers of both physiological and pathological brain processes. The majority of the results from humans with focal epilepsy have focused on HFOs recorded directly from the brain with intracranial EEG (iEEG) in the high gamma (65 - 100 Hz), ripple (100 - 250 Hz), and fast ripple (250 - 600 Hz) frequency ranges. These results are supplemented by reports of HFOs recorded with iEEG in the low gamma (30 - 65Hz) and very high frequency (500 - 2000 Hz) ranges. Visual detection of HFOs is laborious and limited by poor inter-rater agreement; and the need for accurate, reproducible automated HFOs detection is well recognized. In particular, the clinical translation of HFOs as a biomarker of the epileptogenic brain has been limited by the ability to reliably detect and accurately classify HFOs as physiological or pathological. Despite these challenges, there has been significant progress in the field, which is the subject of this review. Furthermore, we provide data and corresponding analytic code in an effort to promote reproducible research and accelerate clinical translation.
- 655 _2
- $a časopisecké články $7 D016428
- 700 1_
- $a Cimbalnik, Jan $u Mayo Systems Electrophysiology Laboratory, Department of Neurology, Mayo Clinic, 200 First St SW, Rochester MN, 55905, USA. International Clinical Research Center, St. Anne's University Hospital, Brno, Czech Republic.
- 700 1_
- $a Worrell, Gregory A $u Mayo Systems Electrophysiology Laboratory, Department of Neurology, Mayo Clinic, 200 First St SW, Rochester MN, 55905, USA. Department of Biomedical Engineering and Physiology, Mayo Clinic, 200 First St SW, Rochester MN, 55905, USA.
- 773 0_
- $w MED00194909 $t Current opinion in biomedical engineering $x 2468-4511 $g Roč. 4, č. - (2017), s. 87-96
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/29532041 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y a $z 0
- 990 __
- $a 20180404 $b ABA008
- 991 __
- $a 20210121105946 $b ABA008
- 999 __
- $a ind $b bmc $g 1287426 $s 1006753
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2017 $b 4 $c - $d 87-96 $e 20170922 $i 2468-4511 $m Current opinion in biomedical engineering $n Curr Opin Biomed Eng $x MED00194909
- LZP __
- $a Pubmed-20180404
