• Je něco špatně v tomto záznamu ?

The enantioselective addition of 1-fluoro-1-nitro(phenylsulfonyl)methane to isatin-derived ketimines

M. Urban, M. Franc, M. Hofmanová, I. Císařová, J. Veselý,

. 2017 ; 15 (43) : 9071-9076.

Jazyk angličtina Země Anglie, Velká Británie

Typ dokumentu časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/bmc18024522

An asymmetric organocatalytic addition of fluorinated phenylsulfonylnitromethane to isatin-derived ketimines was developed. The reaction was efficiently catalyzed by a chiral tertiary amine, cinchonine. This methodology provides a new type of optically active compound with two adjacent quaternary carbon stereocenters in good yield (up to 96%), with moderate diastereoselectivity (up to 5.7 : 1 dr) and excellent enantioselectivity (up to 98/96% ee).

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc18024522
003      
CZ-PrNML
005      
20180718104155.0
007      
ta
008      
180709s2017 enk f 000 0|eng||
009      
AR
024    7_
$a 10.1039/c7ob02408h $2 doi
035    __
$a (PubMed)29083001
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a enk
100    1_
$a Urban, M $u Department of Organic Chemistry, Charles University, Hlavova 8, 12843 Prague, Czech Republic. jxvesely@natur.cuni.cz.
245    14
$a The enantioselective addition of 1-fluoro-1-nitro(phenylsulfonyl)methane to isatin-derived ketimines / $c M. Urban, M. Franc, M. Hofmanová, I. Císařová, J. Veselý,
520    9_
$a An asymmetric organocatalytic addition of fluorinated phenylsulfonylnitromethane to isatin-derived ketimines was developed. The reaction was efficiently catalyzed by a chiral tertiary amine, cinchonine. This methodology provides a new type of optically active compound with two adjacent quaternary carbon stereocenters in good yield (up to 96%), with moderate diastereoselectivity (up to 5.7 : 1 dr) and excellent enantioselectivity (up to 98/96% ee).
650    _2
$a benzensulfonáty $x chemie $7 D001557
650    _2
$a iminy $x chemie $7 D007097
650    _2
$a isatin $x chemie $7 D007510
650    _2
$a methan $x chemie $7 D008697
650    _2
$a nitrily $x chemie $7 D009570
650    _2
$a stereoizomerie $7 D013237
655    _2
$a časopisecké články $7 D016428
700    1_
$a Franc, M $u Department of Organic Chemistry, Charles University, Hlavova 8, 12843 Prague, Czech Republic. jxvesely@natur.cuni.cz.
700    1_
$a Hofmanová, M $u Department of Organic Chemistry, Charles University, Hlavova 8, 12843 Prague, Czech Republic. jxvesely@natur.cuni.cz.
700    1_
$a Císařová, I $u Department of Inorganic Chemistry, Charles University, Hlavova 8, 12843 Prague, Czech Republic.
700    1_
$a Veselý, J $u Department of Organic Chemistry, Charles University, Hlavova 8, 12843 Prague, Czech Republic. jxvesely@natur.cuni.cz.
773    0_
$w MED00007088 $t Organic & biomolecular chemistry $x 1477-0539 $g Roč. 15, č. 43 (2017), s. 9071-9076
856    41
$u https://pubmed.ncbi.nlm.nih.gov/29083001 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y a $z 0
990    __
$a 20180709 $b ABA008
991    __
$a 20180718104455 $b ABA008
999    __
$a ok $b bmc $g 1316653 $s 1021443
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2017 $b 15 $c 43 $d 9071-9076 $i 1477-0539 $m Organic & biomolecular chemistry $n Org Biomol Chem $x MED00007088
LZP    __
$a Pubmed-20180709

Najít záznam

Citační ukazatele

Možnosti archivace