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Facile synthesis and rheological characterization of nanocomposite hyaluronan-organoclay hydrogels
J. Mourycová, KKR. Datta, A. Procházková, M. Plotěná, V. Enev, J. Smilek, J. Másílko, M. Pekař,
International journal of biological macromolecules.
2018 ;
111 (-) :
680-684.
[pub] 20180112
Jazyk angličtina Země Nizozemsko
Typ dokumentu časopisecké články
Perzistentní odkaz
https://www.medvik.cz/link/bmc18033391
- MeSH
- biokompatibilní materiály chemická syntéza chemie MeSH
- hydrogely chemická syntéza chemie MeSH
- kyselina hyaluronová chemická syntéza chemie MeSH
- nanokompozity chemie MeSH
- reologie MeSH
- silikáty hliníku chemická syntéza chemie MeSH
- voda chemie MeSH
- Publikační typ
- časopisecké články MeSH
We report a facile methodology for the synthesis of inorganic-organic hydrogels based on integrative assembly of aminopropyl magnesium phyllosilicate (aminoclay) and sodium salt of hyaluronic acid. The viscoelastic materials produced by electrostatic interactions and crosslinking of hyaluronan in the presence of exfoliated synthetic organoclay results in the formation of gel-like behavior retaining a high amount of water. This was confirmed by a rheological study revealing significant dominance of the elastic response over the entire deformation frequency range used. The mechanical strength of the aminoclay-hyaluronan hydrogels was found to be higher than that for related materials based on poly(vinylpyrrolidone)-aminoclay hydrogels.
Citace poskytuje Crossref.org
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- $a We report a facile methodology for the synthesis of inorganic-organic hydrogels based on integrative assembly of aminopropyl magnesium phyllosilicate (aminoclay) and sodium salt of hyaluronic acid. The viscoelastic materials produced by electrostatic interactions and crosslinking of hyaluronan in the presence of exfoliated synthetic organoclay results in the formation of gel-like behavior retaining a high amount of water. This was confirmed by a rheological study revealing significant dominance of the elastic response over the entire deformation frequency range used. The mechanical strength of the aminoclay-hyaluronan hydrogels was found to be higher than that for related materials based on poly(vinylpyrrolidone)-aminoclay hydrogels.
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