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Exogenous surfactant as a bridge to prolonged "total lung rest" in severely injured patient during extracorporeal membrane oxygenation

P. Sklienka, J. Maca, F. Bursa, J. Neiser, R. Kula, M. Kanova, T. Danek, P. Sevcik,

. 2018 ; 21 (3) : 374-377. [pub] 20180327

Language English Country Japan

Document type Case Reports, Journal Article

E-resources Online Full text

NLK ProQuest Central from 1998-03-01 to 2019-01-31
Medline Complete (EBSCOhost) from 1998-03-01 to 1 year ago
Nursing & Allied Health Database (ProQuest) from 1998-03-01 to 2019-01-31
Health & Medicine (ProQuest) from 1998-03-01 to 2019-01-31

We report a case of a 20-year-old male patient suffering from motorcycle accident complicated by rapid development of severe refractory hypoxemia and hypercapnia due to serious bilateral lung contusions and lacerations. Positive pressure mechanical ventilation induced pressure-dependent massive air leak from disrupted pulmonary tissue. Simultaneous implementation of veno-venous extracorporeal membrane oxygenation together with surfactant application allowed prolonged disconnection of patient from mechanical ventilation ("total lung rest" mode). Despite considerable areas of nonaerated tissue on computed tomography prior to the disconnection from mechanical ventilation, almost total functional recovery of lungs was eventually achieved.

References provided by Crossref.org

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$a We report a case of a 20-year-old male patient suffering from motorcycle accident complicated by rapid development of severe refractory hypoxemia and hypercapnia due to serious bilateral lung contusions and lacerations. Positive pressure mechanical ventilation induced pressure-dependent massive air leak from disrupted pulmonary tissue. Simultaneous implementation of veno-venous extracorporeal membrane oxygenation together with surfactant application allowed prolonged disconnection of patient from mechanical ventilation ("total lung rest" mode). Despite considerable areas of nonaerated tissue on computed tomography prior to the disconnection from mechanical ventilation, almost total functional recovery of lungs was eventually achieved.
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$a Maca, Jan $u Department of Anesthesiology and Intensive Care Medicine, University Hospital Ostrava, 17. listopadu 1790, 708 52, Ostrava, Czech Republic. Department of Intensive Care Medicine and Forensic Studies, Faculty of Medicine, University Ostrava, Ostrava, Czech Republic.
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