-
Something wrong with this record ?
Relationship between dynamic expiratory time constant tau(edyn) and parameters of breathing cycle in pressure support ventilation mode
P. Čandik, D. Rybár, F. Depta, F. Sabol, A. Kolesár, K. Galková, P. Török, V. Doničová, Š. Imrecze, M. Nosáľ, V. Donič
Language English Country Czech Republic
Document type Journal Article
NLK
Directory of Open Access Journals
from 1991
Free Medical Journals
from 1998
ProQuest Central
from 2005-01-01
Medline Complete (EBSCOhost)
from 2006-01-01
Nursing & Allied Health Database (ProQuest)
from 2005-01-01
Health & Medicine (ProQuest)
from 2005-01-01
ROAD: Directory of Open Access Scholarly Resources
from 1998
- MeSH
- Time Factors MeSH
- Middle Aged MeSH
- Humans MeSH
- Respiratory Mechanics physiology MeSH
- Ventilator Weaning methods MeSH
- Retrospective Studies MeSH
- Aged MeSH
- Respiration, Artificial methods MeSH
- Positive-Pressure Respiration methods MeSH
- Exhalation physiology MeSH
- Check Tag
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Aged MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
Study of the relationship between ventilation parameters: monitored expiratory time constant - tau(edyn) and breathing - trigger frequency (f(trig)) and time of breathing cycle (T(cy)) are main goals of this article. Parameters were analyzed during last 4+/-2 h before weaning from ventilation in 66 patients ventilated in pressure support mode (PSV). We have found out, that there exist mathematical relationships, observed during adequate gas exchange, yet not described. Monitored parameters are represented by tau(edyn), f(trig) and T(cy). The analysis showed close negative correlation between T(cy) and f(trig) (R(2)=0.903). This implies that each increasing of tau(edyn) causes decreasing of f(trig) and vice versa. The calculation of regression equation between tau(edyn) and T(cy) outlined that T(cy) = 5.2625 * tau(edyn) + 0.1242 (R(2)=0.85). Regulation of respiratory cycles by the respiratory center in the brain is probably based on evaluation of tau(edyn) as the tau(edyn) probably represents a regulatory element and T(cy) regulated element. It can be assumed, that respiratory center can optimize the work of breathing in order to minimize energy in system patient + ventilator. The unique relationship, described above could be useful in clinical practice for development of new ventilation modes.
Department of Human Physiology Faculty of Medicine Safarik University Košice
Department of Pathophysiology Faculty of Medicine Safarik University Košice
Faculty of Social Sciences and Health Care University of Constantine Philosopher Nitra
References provided by Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc19004044
- 003
- CZ-PrNML
- 005
- 20190212140345.0
- 007
- ta
- 008
- 190124s2018 xr d f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.33549/physiolres.933750 $2 doi
- 035 __
- $a (PubMed)30204464
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a xr
- 100 1_
- $a Čandík, Peter $7 xx0146250 $u Clinic of Anesthesiology and Intensive Medicine, East Slovakian Institute of Cardiovascular Diseases and Faculty of Medicine, Safarik University, Košice
- 245 10
- $a Relationship between dynamic expiratory time constant tau(edyn) and parameters of breathing cycle in pressure support ventilation mode / $c P. Čandik, D. Rybár, F. Depta, F. Sabol, A. Kolesár, K. Galková, P. Török, V. Doničová, Š. Imrecze, M. Nosáľ, V. Donič
- 520 9_
- $a Study of the relationship between ventilation parameters: monitored expiratory time constant - tau(edyn) and breathing - trigger frequency (f(trig)) and time of breathing cycle (T(cy)) are main goals of this article. Parameters were analyzed during last 4+/-2 h before weaning from ventilation in 66 patients ventilated in pressure support mode (PSV). We have found out, that there exist mathematical relationships, observed during adequate gas exchange, yet not described. Monitored parameters are represented by tau(edyn), f(trig) and T(cy). The analysis showed close negative correlation between T(cy) and f(trig) (R(2)=0.903). This implies that each increasing of tau(edyn) causes decreasing of f(trig) and vice versa. The calculation of regression equation between tau(edyn) and T(cy) outlined that T(cy) = 5.2625 * tau(edyn) + 0.1242 (R(2)=0.85). Regulation of respiratory cycles by the respiratory center in the brain is probably based on evaluation of tau(edyn) as the tau(edyn) probably represents a regulatory element and T(cy) regulated element. It can be assumed, that respiratory center can optimize the work of breathing in order to minimize energy in system patient + ventilator. The unique relationship, described above could be useful in clinical practice for development of new ventilation modes.
- 650 _2
- $a senioři $7 D000368
- 650 _2
- $a vydechnutí $x fyziologie $7 D045853
- 650 _2
- $a ženské pohlaví $7 D005260
- 650 _2
- $a lidé $7 D006801
- 650 _2
- $a mužské pohlaví $7 D008297
- 650 _2
- $a lidé středního věku $7 D008875
- 650 _2
- $a ventilace umělá s výdechovým přetlakem $x metody $7 D011175
- 650 _2
- $a umělé dýchání $x metody $7 D012121
- 650 _2
- $a mechanika dýchání $x fyziologie $7 D015656
- 650 _2
- $a retrospektivní studie $7 D012189
- 650 _2
- $a časové faktory $7 D013997
- 650 _2
- $a odpojení od ventilátoru $x metody $7 D015300
- 655 _2
- $a časopisecké články $7 D016428
- 700 1_
- $a Rybár, Dušan. $7 xx0232310 $u Clinic of Anesthesiology and Intensive Medicine, East Slovakian Institute of Cardiovascular Diseases and Faculty of Medicine, Safarik University, Košice
- 700 1_
- $a Depta, Filip. $7 xx0232413 $u Clinic of Anesthesiology and Intensive Medicine, East Slovakian Institute of Cardiovascular Diseases and Faculty of Medicine, Safarik University, Košice
- 700 1_
- $a Sabol, František $7 xx0129265 $u Clinic of Cardiac Surgery, East Slovakian Institute of Cardiovascular Diseases and Faculty of Medicine, Safarik University, Košice
- 700 1_
- $a Kolesár, Adrian $7 xx0105461 $u Clinic of Cardiac Surgery, East Slovakian Institute of Cardiovascular Diseases and Faculty of Medicine, Safarik University, Košice
- 700 1_
- $a Galková, Katarína $7 xx0232311 $u Faculty of Social Sciences and Health Care, University of Constantine Philosopher, Nitra
- 700 1_
- $a Török, Pavol $7 xx0119602 $u Clinic of Anesthesiology and Intensive Medicine, East Slovakian Institute of Cardiovascular Diseases and Faculty of Medicine, Safarik University, Košice; Faculty of Social Sciences and Health Care, University of Constantine Philosopher, Nitra
- 700 1_
- $a Doničová, Viera $7 xx0063735 $u Department of Pathophysiology, Faculty of Medicine, Safarik University, Košice
- 700 1_
- $a Imrecze, Štefan $7 xx0232520 $u Clinic of Anesthesiology and Intensive Medicine, East Slovakian Institute of Cardiovascular Diseases and Faculty of Medicine, Safarik University, Košice
- 700 1_
- $a Nosáľ, Martin $7 xx0232513 $u Clinic of Anesthesiology and Intensive Medicine, East Slovakian Institute of Cardiovascular Diseases and Faculty of Medicine, Safarik University, Košice
- 700 1_
- $a Donič, Viliam $7 xx0063734 $u Department of Human Physiology, Faculty of Medicine, Safarik University, Košice
- 773 0_
- $w MED00003824 $t Physiological research $x 1802-9973 $g Roč. 67, č. 6 (2018), s. 875-879
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/30204464 $y Pubmed
- 910 __
- $a ABA008 $b A 4120 $c 266 $y 4 $z 0
- 990 __
- $a 20190124 $b ABA008
- 991 __
- $a 20190208101249 $b ABA008
- 999 __
- $a ok $b bmc $g 1375751 $s 1042222
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2018 $b 67 $c 6 $d 875-879 $e 20180911 $i 1802-9973 $m Physiological research $n Physiol. Res. (Print) $x MED00003824
- LZP __
- $b NLK111 $a Pubmed-20190124