Recently, porous carriers are used in the pharmaceuti-cal technology due to their promising properties ‒ large specific surface area, porous structure, suitable technologi-cal properties, etc. They participate in the preparation of liquisolid systems, self-emulsifying drug delivery systems, etc., which are capable to deliver and release the drug in the required manner to the biological system. One of the most widely used porous carrier is microcrystalline cellu-lose. Other perspective carriers are magnesium alumi-nometasilicates, which show several advantageous proper-ties. Also calcium hydrogen phosphate represents a com-monly used carrier with easy compressibility, rapid disin-tegration or improved flow properties. Due to their large specific surface area, mesoporous silicates and silica aero-gels are also often used. The clay materials in the form of natural or modified materials with a structure of hollow nanotubes provide a suitable carrier of the drug. This arti-cle summarizes basic information about available porous carriers and their characterizations, as well as available application studies on the given topic.

Ústav technologie léků Farmaceutická fakulta Veterinární a farmaceutická univerzita Brno Palackého třída 1946 1 612 42 Brno

Porous carriers used in pharmaceutictTechnology

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