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Optical coherence tomography in STEMI with bioresorbable scaffold: possible cause of coronary flow impairment? A sub-study from the Prague 19 trial
M. Loffi, P. Tousek, T. Budesinsky, L. Lisa, A. Santangelo, P. Widimsky, V. Kocka,
Language English Country Japan
Document type Journal Article, Multicenter Study, Randomized Controlled Trial
NLK
ProQuest Central
from 2000-01-01 to 2018-12-31
Medline Complete (EBSCOhost)
from 2003-03-01 to 1 year ago
Health & Medicine (ProQuest)
from 2000-01-01 to 2018-12-31
- MeSH
- Time Factors MeSH
- Everolimus pharmacology MeSH
- ST Elevation Myocardial Infarction diagnosis physiopathology surgery MeSH
- Coronary Angiography MeSH
- Percutaneous Coronary Intervention MeSH
- Coronary Vessels diagnostic imaging surgery MeSH
- Coronary Circulation physiology MeSH
- Humans MeSH
- Tomography, Optical Coherence methods MeSH
- Prospective Studies MeSH
- Prosthesis Design MeSH
- Regional Blood Flow physiology MeSH
- Drug-Eluting Stents MeSH
- Tissue Scaffolds * MeSH
- Absorbable Implants * MeSH
- Treatment Outcome MeSH
- Check Tag
- Humans MeSH
- Male MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Multicenter Study MeSH
- Randomized Controlled Trial MeSH
This study assessed the Optical Coherence Tomography (OCT) impact on the coronary flow in ST-elevation myocardial infarction (STEMI) after bioresorbable scaffold implantation. Only few data about OCT use in STEMI are available and coronary flow before and after OCT is not well studied yet. 54 patients with OCT performed at the end of procedure from the Prague 19 trial were selected and coronary flow was evaluated as TIMI frame count (TFC) before and just after OCT. Significant increase in TIMI frame count after OCT [from 9.5 (6.75-12.25) to 11.5 (8-15.25) frames; p = 0.001] and high verapamil administration (18%) was reported. OCT at the end of primary percutaneous coronary intervention with bioresorbable scaffold is a feasible procedure. However, it seems to be associated with flow deterioration.
References provided by Crossref.org
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- $a This study assessed the Optical Coherence Tomography (OCT) impact on the coronary flow in ST-elevation myocardial infarction (STEMI) after bioresorbable scaffold implantation. Only few data about OCT use in STEMI are available and coronary flow before and after OCT is not well studied yet. 54 patients with OCT performed at the end of procedure from the Prague 19 trial were selected and coronary flow was evaluated as TIMI frame count (TFC) before and just after OCT. Significant increase in TIMI frame count after OCT [from 9.5 (6.75-12.25) to 11.5 (8-15.25) frames; p = 0.001] and high verapamil administration (18%) was reported. OCT at the end of primary percutaneous coronary intervention with bioresorbable scaffold is a feasible procedure. However, it seems to be associated with flow deterioration.
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