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Synthesis of Base-Modified dNTPs Through Cross-Coupling Reactions and Their Polymerase Incorporation to DNA
P. Ménová, H. Cahová, M. Vrábel, M. Hocek,
Jazyk angličtina Země Spojené státy americké
Typ dokumentu časopisecké články, práce podpořená grantem
- MeSH
- DNA-dependentní DNA-polymerasy metabolismus MeSH
- DNA biosyntéza chemie MeSH
- halogenace MeSH
- nukleotidy biosyntéza chemie MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
Synthesis of base-modified dNTPs through the Suzuki or Sonogashira cross-coupling reactions of halogenated dNTPs with boronic acids or alkynes is reported, as well as the use of these modified dNTPs in polymerase incorporations to oligonucleotides or DNA by primer extension or PCR.
Citace poskytuje Crossref.org
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