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Comment on 'Naked mole-rat mortality rates defy Gompertzian laws by not increasing with age'

P. Dammann, A. Scherag, N. Zak, K. Szafranski, S. Holtze, S. Begall, H. Burda, HA. Kestler, T. Hildebrandt, M. Platzer,

. 2019 ; 8 (-) : . [pub] 20190709

Jazyk angličtina Země Velká Británie

Typ dokumentu časopisecké články, práce podpořená grantem, komentáře

Perzistentní odkaz   https://www.medvik.cz/link/bmc19044676

Grantová podpora
DA 992/3-1 Deutsche Forschungsgemeinschaft - International
PL 173/8-1 Deutsche Forschungsgemeinschaft - International

Ruby et al. recently analyzed historical lifespan data on more than 3200 naked mole-rats, collected over a total observation period of about 38 years (Ruby et al., 2018). They report that mortality hazards do not seem to increase across the full range of their so-far-observed lifespan, and conclude that this defiance of Gompertz's law 'uniquely identifies the naked mole-rat as a non-aging mammal'. Here, we explain why we believe this conclusion is premature.

Citace poskytuje Crossref.org

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$a Ruby et al. recently analyzed historical lifespan data on more than 3200 naked mole-rats, collected over a total observation period of about 38 years (Ruby et al., 2018). They report that mortality hazards do not seem to increase across the full range of their so-far-observed lifespan, and conclude that this defiance of Gompertz's law 'uniquely identifies the naked mole-rat as a non-aging mammal'. Here, we explain why we believe this conclusion is premature.
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$a Scherag, André $u Institute of Medical Statistics, Computer and Data Sciences (IMSID), Jena University Hospital, Jena, Germany.
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$a Zak, Nikolay $u Moscow Society of Naturalists, Moscow, Russia.
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$a Szafranski, Karol $u Leibniz Institute on Aging - Fritz Lipmann Institute, Jena, Germany.
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$a Holtze, Susanne $u Department of Reproduction Management, Leibniz Institute for Zoo and Wildlife Research, Berlin, Germany.
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$a Begall, Sabine $u Department of General Zoology, Faculty of Biology, University of Duisburg-Essen, Essen, Germany.
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$a Burda, Hynek $u Department Game Management and Wildlife Biology, Faculty of Forestry and Wood Sciences, Czech University of Life Sciences, Prague, Czech Republic.
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$a Kestler, Hans A $u Leibniz Institute on Aging - Fritz Lipmann Institute, Jena, Germany. Institute of Medical Systems Biology, Ulm University, Ulm, Germany.
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$a Hildebrandt, Thomas $u Department of Reproduction Management, Leibniz Institute for Zoo and Wildlife Research, Berlin, Germany.
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$a Platzer, Matthias $u Leibniz Institute on Aging - Fritz Lipmann Institute, Jena, Germany.
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