• Je něco špatně v tomto záznamu ?

Gastric fluid used to assess changes during the latency period in preterm prelabor rupture of membranes

I. Musilova, C. Andrys, H. Hornychova, L. Pliskova, M. Drahosova, B. Zednikova, R. Bolehovska, T. Faist, B. Jacobsson, M. Kacerovsky,

. 2018 ; 84 (2) : 240-247. [pub] 20180531

Jazyk angličtina Země Spojené státy americké

Typ dokumentu časopisecké články, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/bmc19045415
E-zdroje Online Plný text

NLK Free Medical Journals od 1967 do Před 1 rokem
ProQuest Central od 2016-01-01 do Před 1 rokem
Health & Medicine (ProQuest) od 2016-01-01 do Před 1 rokem
Public Health Database (ProQuest) od 2016-01-01 do Před 1 rokem

Odkazy

PubMed 29892034
DOI 10.1038/s41390-018-0073-1
Knihovny.cz E-zdroje

OBJECTIVE: To determine changes in the intraamniotic environment during the latency period using paired amniotic and gastric fluid samples in pregnancies complicated by preterm prelabor rupture of membranes (PPROM). METHODS: A total of 34 women with singleton pregnancies complicated by PPROM prior to 34 weeks were included in the study. Amniotic fluid was obtained by transabdominal amniocentesis at the time of admission. Immediately after delivery, umbilical cord blood and gastric fluid were obtained. RESULT: Microorganisms in amniotic and gastric fluid samples were found in 38% and 59% of women, respectively. Bedside IL-6 levels were higher in amniotic than in gastric fluid in pregnancies without fetal inflammatory response syndrome (FIRS) (263 pg/mL vs. 50 pg/mL; p < 0.0001), but not in pregnancies with FIRS (318 pg/mL vs. 444 pg/mL; p = 0.91). Funisitis and FIRS was associated with the highest bedside IL-6 levels in gastric fluid. A gastric fluid bedside IL-6 level of 275 pg/mL was found to be the ideal cutoff value to predict funisitis and FIRS. CONCLUSIONS: The microbial and inflammatory status of the intraamniotic compartment changes during the latency period in PPROM. Bedside IL-6 assessment of gastric fluid may be useful in the rapid diagnosis of funisitis and FIRS.

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc19045415
003      
CZ-PrNML
005      
20200602104837.0
007      
ta
008      
200109s2018 xxu f 000 0|eng||
009      
AR
024    7_
$a 10.1038/s41390-018-0073-1 $2 doi
035    __
$a (PubMed)29892034
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xxu
100    1_
$a Kacerovská Musilová, Ivana $7 pag2013740751 $u Department of Obstetrics and Gynecology, University Hospital in Hradec Kralove, Charles University, Faculty of Medicine Hradec Kralove, Hradec Kralove, Czech Republic.
245    10
$a Gastric fluid used to assess changes during the latency period in preterm prelabor rupture of membranes / $c I. Musilova, C. Andrys, H. Hornychova, L. Pliskova, M. Drahosova, B. Zednikova, R. Bolehovska, T. Faist, B. Jacobsson, M. Kacerovsky,
520    9_
$a OBJECTIVE: To determine changes in the intraamniotic environment during the latency period using paired amniotic and gastric fluid samples in pregnancies complicated by preterm prelabor rupture of membranes (PPROM). METHODS: A total of 34 women with singleton pregnancies complicated by PPROM prior to 34 weeks were included in the study. Amniotic fluid was obtained by transabdominal amniocentesis at the time of admission. Immediately after delivery, umbilical cord blood and gastric fluid were obtained. RESULT: Microorganisms in amniotic and gastric fluid samples were found in 38% and 59% of women, respectively. Bedside IL-6 levels were higher in amniotic than in gastric fluid in pregnancies without fetal inflammatory response syndrome (FIRS) (263 pg/mL vs. 50 pg/mL; p < 0.0001), but not in pregnancies with FIRS (318 pg/mL vs. 444 pg/mL; p = 0.91). Funisitis and FIRS was associated with the highest bedside IL-6 levels in gastric fluid. A gastric fluid bedside IL-6 level of 275 pg/mL was found to be the ideal cutoff value to predict funisitis and FIRS. CONCLUSIONS: The microbial and inflammatory status of the intraamniotic compartment changes during the latency period in PPROM. Bedside IL-6 assessment of gastric fluid may be useful in the rapid diagnosis of funisitis and FIRS.
650    _2
$a dospělí $7 D000328
650    _2
$a amniocentéza $7 D000649
650    _2
$a plodová voda $x chemie $x mikrobiologie $7 D000653
650    _2
$a biologické markery $x analýza $7 D015415
650    _2
$a tělesné tekutiny $7 D001826
650    _2
$a Chlamydia trachomatis $7 D002692
650    _2
$a chorioamnionitida $7 D002821
650    _2
$a ženské pohlaví $7 D005260
650    _2
$a fetální krev $x chemie $7 D005312
650    12
$a předčasný odtok plodové vody $7 D005322
650    _2
$a žaludeční šťáva $x chemie $x mikrobiologie $7 D005750
650    _2
$a lidé $7 D006801
650    _2
$a novorozenec $7 D007231
650    _2
$a zánět $7 D007249
650    _2
$a interleukin-6 $x analýza $7 D015850
650    _2
$a Mycoplasma hominis $7 D019535
650    _2
$a těhotenství $7 D011247
650    _2
$a prospektivní studie $7 D011446
650    _2
$a žaludek $x mikrobiologie $7 D013270
650    _2
$a syndrom $7 D013577
650    _2
$a Ureaplasma $7 D014509
655    _2
$a časopisecké články $7 D016428
655    _2
$a práce podpořená grantem $7 D013485
700    1_
$a Andrys, Ctirad $u Department of Clinical Immunology and Allergy, University Hospital in Hradec Kralove, Charles University, Faculty of Medicine Hradec Kralove, Hradec Kralove, Czech Republic.
700    1_
$a Hornychova, Helena $u Fingerland's Department of Pathology, University Hospital in Hradec Kralove, Charles University, Faculty of Medicine Hradec Kralove, Hradec Kralove, Czech Republic.
700    1_
$a Pliskova, Lenka $u Institute of Clinical Biochemistry and Diagnostics, University Hospital in Hradec Kralove, Charles University, Faculty of Medicine Hradec Kralove, Hradec Kralove, Czech Republic.
700    1_
$a Drahosova, Marcela $u Department of Clinical Immunology and Allergy, University Hospital in Hradec Kralove, Charles University, Faculty of Medicine Hradec Kralove, Hradec Kralove, Czech Republic.
700    1_
$a Zednikova, Barbora $u Department of Clinical Immunology and Allergy, University Hospital in Hradec Kralove, Charles University, Faculty of Medicine Hradec Kralove, Hradec Kralove, Czech Republic.
700    1_
$a Bolehovska, Radka $u Institute of Clinical Biochemistry and Diagnostics, University Hospital in Hradec Kralove, Charles University, Faculty of Medicine Hradec Kralove, Hradec Kralove, Czech Republic.
700    1_
$a Faist, Tomas $u Department of Obstetrics and Gynecology, University Hospital in Hradec Kralove, Charles University, Faculty of Medicine Hradec Kralove, Hradec Kralove, Czech Republic.
700    1_
$a Jacobsson, Bo $u Department of Obstetrics and Gynecology, Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden. Department of Genetics and Bioinformatics, Domain of Health Data and Digitalization, Institute of Public Health, Oslo, Norway.
700    1_
$a Kacerovsky, Marian $u Department of Obstetrics and Gynecology, University Hospital in Hradec Kralove, Charles University, Faculty of Medicine Hradec Kralove, Hradec Kralove, Czech Republic. kacermar@fnhk.cz. Biomedical Research Center, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic. kacermar@fnhk.cz.
773    0_
$w MED00003741 $t Pediatric research $x 1530-0447 $g Roč. 84, č. 2 (2018), s. 240-247
856    41
$u https://pubmed.ncbi.nlm.nih.gov/29892034 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y a $z 0
990    __
$a 20200109 $b ABA008
991    __
$a 20200602104833 $b ABA008
999    __
$a ok $b bmc $g 1483684 $s 1084088
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2018 $b 84 $c 2 $d 240-247 $e 20180531 $i 1530-0447 $m Pediatric research $n Pediatr Res $x MED00003741
LZP    __
$a Pubmed-20200109

Najít záznam

Citační ukazatele

Možnosti archivace