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Global guideline for the diagnosis and management of mucormycosis: an initiative of the European Confederation of Medical Mycology in cooperation with the Mycoses Study Group Education and Research Consortium
OA. Cornely, A. Alastruey-Izquierdo, D. Arenz, SCA. Chen, E. Dannaoui, B. Hochhegger, M. Hoenigl, HE. Jensen, K. Lagrou, RE. Lewis, SC. Mellinghoff, M. Mer, ZD. Pana, D. Seidel, DC. Sheppard, R. Wahba, M. Akova, A. Alanio, AMS. Al-Hatmi, S....
Jazyk angličtina Země Spojené státy americké
Typ dokumentu časopisecké články, směrnice pro lékařskou praxi, přehledy
NLK
ProQuest Central
od 2001-08-01 do Před 2 měsíci
Nursing & Allied Health Database (ProQuest)
od 2001-08-01 do Před 2 měsíci
Health & Medicine (ProQuest)
od 2001-08-01 do Před 2 měsíci
Public Health Database (ProQuest)
od 2001-08-01 do Před 2 měsíci
- MeSH
- lidé MeSH
- management nemoci MeSH
- mukormykóza diagnóza epidemiologie mikrobiologie terapie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
- směrnice pro lékařskou praxi MeSH
Mucormycosis is a difficult to diagnose rare disease with high morbidity and mortality. Diagnosis is often delayed, and disease tends to progress rapidly. Urgent surgical and medical intervention is lifesaving. Guidance on the complex multidisciplinary management has potential to improve prognosis, but approaches differ between health-care settings. From January, 2018, authors from 33 countries in all United Nations regions analysed the published evidence on mucormycosis management and provided consensus recommendations addressing differences between the regions of the world as part of the "One World One Guideline" initiative of the European Confederation of Medical Mycology (ECMM). Diagnostic management does not differ greatly between world regions. Upon suspicion of mucormycosis appropriate imaging is strongly recommended to document extent of disease and is followed by strongly recommended surgical intervention. First-line treatment with high-dose liposomal amphotericin B is strongly recommended, while intravenous isavuconazole and intravenous or delayed release tablet posaconazole are recommended with moderate strength. Both triazoles are strongly recommended salvage treatments. Amphotericin B deoxycholate is recommended against, because of substantial toxicity, but may be the only option in resource limited settings. Management of mucormycosis depends on recognising disease patterns and on early diagnosis. Limited availability of contemporary treatments burdens patients in low and middle income settings. Areas of uncertainty were identified and future research directions specified.
CECAD Cluster of Excellence University of Cologne Cologne Germany
Center of Expertise in Microbiology Infection Biology and Antimicrobial Pharmacology Tehran Iran
Centre of Expertise in Mycology RadboudUMC Canisius Wilhelmina Hospital Nijmegen The Netherlands
Clinical Trials Center Cologne University Hospital of Cologne Cologne Germany
Department 1 of Internal Medicine University Hospital of Cologne Cologne Germany
Department for Internal Medicine 2 University Hospital Würzburg Würzburg Germany
Department of General Visceral and Cancer Surgery University Hospital of Cologne Cologne Germany
Department of Hematology Oncology and Palliative Care Klinikum Ernst von Bergmann Potsdam Germany
Department of Infectious Diseases Alfred Health and Monash University Melbourne Australia
Department of Infectious Diseases Hacettepe University School of Medicine Ankara Turkey
Department of Infectious Diseases Singapore General Hospital Singapur Singapore
Department of Internal Medicine Hematology Oncology Goethe University Frankfurt Frankfurt Germany
Department of Internal Medicine Infectious Diseases Goethe University Frankfurt Frankfurt Germany
Department of Internal Medicine Universidade Federal do Rio de Janeiro Rio de Janeiro Brazil
Department of Medical Microbiology Hacettepe University School of Medicine Sıhhiye Ankara Turkey
Department of Medicine Faculty of Medicine Siriraj Hospital Mahidol University Bangkok Thailand
Division of Infectious Diseases The Children's Hospital of Philadelphia Philadelphia PA USA
Faculty of Biology Medicine and Health The University of Manchester Manchester UK
Faculty of Health and Medical Sciences University of Copenhagen Copenhagen Denmark
Fungus Testing Laboratory University of Texas Health Science Center San Antonio TX USA
German Centre for Infection Research partner site Bonn Cologne Cologne Germany
Hämatologie and Internistische Onkologie Lukas Krankenhaus Bünde Onkologische Ambulanz Bünde Germany
Hippokration General Hospital Thessaloniki Greece
Infectious Diseases Clinic Vedanta Institute of Medical Sciences Navarangpura Ahmeddabad India
Infectious Diseases Unit Istituto Giannina Gaslini Children's Hospital Genoa Italy
Infectious Diseases Unit Szent Istvan and Szent Laszlo Hospital Budapest Hungary
Infectious Diseases Unit Tel Aviv Medical Center Tel Aviv Israel
Institute of Hematology and Blood Transfusion Prague Czech Republic
Instituto de Investigación v Sanitaria Gregorio Marañón Madrid Spain
Laboratory of Antimicrobial Chemotherapy Ion Ionescu de la Brad University Iaşi Romania
Los Angeles County and University of Southern California Medical Center Los Angeles CA USA
Medicine Department School of Medicine Universidad Complutense de Madrid Madrid Spain
Ministry of Health Directorate General of Health Services Ibri Oman
Public Health Wales Microbiology Cardiff UHW Heath Park Cardiff UK
Radiology Universidade Federal de Ciências da Saúde de Porto Alegre Porto Alegre Brazil
Sackler Faculty of Medicine Tel Aviv University Tel Aviv Israel
School of Medicine and Pharmacy University Mohammed the fifth Hay Riad Rabat Morocco
UK NHS Mycology Reference Centre Manchester University NHS Foundation Trust Manchester UK
University of Melbourne Melbourne VIC Australia
Westerdijk Fungal Biodiversity Institute Utrecht The Netherlands
Citace poskytuje Crossref.org
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- $a Cornely, Oliver A $u Department I of Internal Medicine, University Hospital of Cologne, Cologne, Germany; German Centre for Infection Research (DZIF) partner site Bonn-Cologne, Cologne, Germany; CECAD Cluster of Excellence, University of Cologne, Cologne, Germany; Clinical Trials Center Cologne, University Hospital of Cologne, Cologne, Germany. Electronic address: oliver.cornely@uk-koeln.de.
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- $a Global guideline for the diagnosis and management of mucormycosis: an initiative of the European Confederation of Medical Mycology in cooperation with the Mycoses Study Group Education and Research Consortium / $c OA. Cornely, A. Alastruey-Izquierdo, D. Arenz, SCA. Chen, E. Dannaoui, B. Hochhegger, M. Hoenigl, HE. Jensen, K. Lagrou, RE. Lewis, SC. Mellinghoff, M. Mer, ZD. Pana, D. Seidel, DC. Sheppard, R. Wahba, M. Akova, A. Alanio, AMS. Al-Hatmi, S. Arikan-Akdagli, H. Badali, R. Ben-Ami, A. Bonifaz, S. Bretagne, E. Castagnola, M. Chayakulkeeree, AL. Colombo, DE. Corzo-León, L. Drgona, AH. Groll, J. Guinea, CP. Heussel, AS. Ibrahim, SS. Kanj, N. Klimko, M. Lackner, F. Lamoth, F. Lanternier, C. Lass-Floerl, DG. Lee, T. Lehrnbecher, BE. Lmimouni, M. Mares, G. Maschmeyer, JF. Meis, J. Meletiadis, CO. Morrissey, M. Nucci, R. Oladele, L. Pagano, A. Pasqualotto, A. Patel, Z. Racil, M. Richardson, E. Roilides, M. Ruhnke, S. Seyedmousavi, N. Sidharthan, N. Singh, J. Sinko, A. Skiada, M. Slavin, R. Soman, B. Spellberg, W. Steinbach, BH. Tan, AJ. Ullmann, JJ. Vehreschild, MJGT. Vehreschild, TJ. Walsh, PL. White, NP. Wiederhold, T. Zaoutis, A. Chakrabarti, Mucormycosis ECMM MSG Global Guideline Writing Group,
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- $a Mucormycosis is a difficult to diagnose rare disease with high morbidity and mortality. Diagnosis is often delayed, and disease tends to progress rapidly. Urgent surgical and medical intervention is lifesaving. Guidance on the complex multidisciplinary management has potential to improve prognosis, but approaches differ between health-care settings. From January, 2018, authors from 33 countries in all United Nations regions analysed the published evidence on mucormycosis management and provided consensus recommendations addressing differences between the regions of the world as part of the "One World One Guideline" initiative of the European Confederation of Medical Mycology (ECMM). Diagnostic management does not differ greatly between world regions. Upon suspicion of mucormycosis appropriate imaging is strongly recommended to document extent of disease and is followed by strongly recommended surgical intervention. First-line treatment with high-dose liposomal amphotericin B is strongly recommended, while intravenous isavuconazole and intravenous or delayed release tablet posaconazole are recommended with moderate strength. Both triazoles are strongly recommended salvage treatments. Amphotericin B deoxycholate is recommended against, because of substantial toxicity, but may be the only option in resource limited settings. Management of mucormycosis depends on recognising disease patterns and on early diagnosis. Limited availability of contemporary treatments burdens patients in low and middle income settings. Areas of uncertainty were identified and future research directions specified.
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- 700 1_
- $a Hochhegger, Bruno $u Radiology, Hospital São Lucas da Pontificia Universidade Catolica do Rio Grande do Sul (PUCRS), Escola de Medicina, Porto Alegre, Brazil; Radiology, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, Brazil.
- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
- $a Mellinghoff, Sibylle C $u Department I of Internal Medicine, University Hospital of Cologne, Cologne, Germany; CECAD Cluster of Excellence, University of Cologne, Cologne, Germany.
- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
- $a Al-Hatmi, Abdullah M S $u Westerdijk Fungal Biodiversity Institute, Utrecht, The Netherlands; Centre of Expertise in Mycology RadboudUMC/Canisius Wilhelmina Hospital, Nijmegen, The Netherlands; Ministry of Health, Directorate General of Health Services, Ibri, Oman.
- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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