-
Je něco špatně v tomto záznamu ?
Psychoactive pharmaceuticals in aquatic systems: A comparative assessment of environmental monitoring approaches for water and fish
K. Grabicová, R. Grabic, G. Fedorova, J. Kolářová, J. Turek, BW. Brooks, T. Randák,
Jazyk angličtina Země Velká Británie
Typ dokumentu časopisecké články
- MeSH
- chemické látky znečišťující vodu analýza MeSH
- léčivé přípravky * MeSH
- lidé MeSH
- monitorování životního prostředí MeSH
- velkoměsta MeSH
- voda MeSH
- zvířata MeSH
- Check Tag
- lidé MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Česká republika MeSH
- velkoměsta MeSH
Environmental monitoring and surveillance studies of pharmaceuticals routinely examine occurrence of substances without current information on human consumption patterns. We selected 10 streams with diverse annual flows and differentially influenced by population densities to examine surface water occurrence and fish accumulation of select psychoactive medicines, for which consumption is increasing in the Czech Republic. We then tested whether passive sampling can provide a useful surrogate for exposure to these substances through grab sampling, body burdens of young of year fish, and tissue specific accumulation of these psychoactive contaminants. We identified a statistically significant (p < 0.05) relationship between ambient grab samples and passive samplers in these streams when psychoactive contaminants were commonly quantitated by targeted liquid chromatography with tandem mass spectrometry, though we did not observe relationships between passive samplers and tissue specific pharmaceutical accumulation. We further observed smaller lotic systems with elevated contamination when municipal effluent discharges from more highly populated cities contributed a greater extent of instream flows. These findings identify the importance of understanding age and species specific differences in fish uptake, internal disposition, metabolism and elimination of psychoactive drugs across surface water quality gradients.
Citace poskytuje Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc20024977
- 003
- CZ-PrNML
- 005
- 20201222153631.0
- 007
- ta
- 008
- 201125s2020 xxk f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.1016/j.envpol.2020.114150 $2 doi
- 035 __
- $a (PubMed)32062094
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a xxk
- 100 1_
- $a Grabicová, Kateřina $u University of South Bohemia in Ceske Budejovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Zatisi 728/II, CZ-389 25, Vodnany, Czech Republic. Electronic address: grabicova@frov.jcu.cz.
- 245 10
- $a Psychoactive pharmaceuticals in aquatic systems: A comparative assessment of environmental monitoring approaches for water and fish / $c K. Grabicová, R. Grabic, G. Fedorova, J. Kolářová, J. Turek, BW. Brooks, T. Randák,
- 520 9_
- $a Environmental monitoring and surveillance studies of pharmaceuticals routinely examine occurrence of substances without current information on human consumption patterns. We selected 10 streams with diverse annual flows and differentially influenced by population densities to examine surface water occurrence and fish accumulation of select psychoactive medicines, for which consumption is increasing in the Czech Republic. We then tested whether passive sampling can provide a useful surrogate for exposure to these substances through grab sampling, body burdens of young of year fish, and tissue specific accumulation of these psychoactive contaminants. We identified a statistically significant (p < 0.05) relationship between ambient grab samples and passive samplers in these streams when psychoactive contaminants were commonly quantitated by targeted liquid chromatography with tandem mass spectrometry, though we did not observe relationships between passive samplers and tissue specific pharmaceutical accumulation. We further observed smaller lotic systems with elevated contamination when municipal effluent discharges from more highly populated cities contributed a greater extent of instream flows. These findings identify the importance of understanding age and species specific differences in fish uptake, internal disposition, metabolism and elimination of psychoactive drugs across surface water quality gradients.
- 650 _2
- $a zvířata $7 D000818
- 650 _2
- $a monitorování životního prostředí $7 D004784
- 650 _2
- $a lidé $7 D006801
- 650 12
- $a léčivé přípravky $7 D004364
- 650 _2
- $a voda $7 D014867
- 650 _2
- $a chemické látky znečišťující vodu $x analýza $7 D014874
- 651 _2
- $a velkoměsta $7 D002947
- 651 _2
- $a Česká republika $7 D018153
- 655 _2
- $a časopisecké články $7 D016428
- 700 1_
- $a Grabic, Roman $u University of South Bohemia in Ceske Budejovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Zatisi 728/II, CZ-389 25, Vodnany, Czech Republic.
- 700 1_
- $a Fedorova, Ganna $u University of South Bohemia in Ceske Budejovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Zatisi 728/II, CZ-389 25, Vodnany, Czech Republic.
- 700 1_
- $a Kolářová, Jitka $u University of South Bohemia in Ceske Budejovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Zatisi 728/II, CZ-389 25, Vodnany, Czech Republic.
- 700 1_
- $a Turek, Jan $u University of South Bohemia in Ceske Budejovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Zatisi 728/II, CZ-389 25, Vodnany, Czech Republic.
- 700 1_
- $a Brooks, Bryan W $u University of South Bohemia in Ceske Budejovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Zatisi 728/II, CZ-389 25, Vodnany, Czech Republic; Department of Environmental Science, Institute of Biomedical Studies, Center for Reservoir and Aquatic Systems Research, Baylor University, Waco, TX, 76798, USA.
- 700 1_
- $a Randák, Tomáš $u University of South Bohemia in Ceske Budejovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Zatisi 728/II, CZ-389 25, Vodnany, Czech Republic.
- 773 0_
- $w MED00001554 $t Environmental pollution (Barking, Essex : 1987) $x 1873-6424 $g Roč. 261, č. - (2020), s. 114150
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/32062094 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y a $z 0
- 990 __
- $a 20201125 $b ABA008
- 991 __
- $a 20201222153627 $b ABA008
- 999 __
- $a ok $b bmc $g 1599122 $s 1115663
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2020 $b 261 $c - $d 114150 $e 20200207 $i 1873-6424 $m Environmental pollution (1987) $n Environ. pollut. (1987) $x MED00001554
- LZP __
- $a Pubmed-20201125