-
Je něco špatně v tomto záznamu ?
Solid organ transplantation after hematopoietic stem cell transplantation in childhood: A multicentric retrospective survey
M. Faraci, A. Bertaina, A. Dalissier, M. Ifversen, A. Schulz, A. Gennery, B. Burkhardt, I. Badell Serra, C. Diaz-de-Heredia, E. Lanino, AC. Lankester, B. Gruhn, S. Matthes-Martin, JS. Kühl, S. Varotto, C. Paillard, A. Guilmatre, A. Sastre, M....
Jazyk angličtina Země Spojené státy americké
Typ dokumentu časopisecké články, multicentrická studie
NLK
Free Medical Journals
od 2001 do 2022
Wiley Free Content
od 2001 do 2022
ROAD: Directory of Open Access Scholarly Resources
od 2001
PubMed
30586230
DOI
10.1111/ajt.15240
Knihovny.cz E-zdroje
- MeSH
- alografty MeSH
- autologní štěp MeSH
- dítě MeSH
- kohortové studie MeSH
- kojenec MeSH
- lidé MeSH
- míra přežití MeSH
- mladiství MeSH
- nemoc štěpu proti hostiteli etiologie chirurgie MeSH
- předškolní dítě MeSH
- proporcionální rizikové modely MeSH
- průzkumy a dotazníky MeSH
- retrospektivní studie MeSH
- transplantace hematopoetických kmenových buněk škodlivé účinky MeSH
- transplantace jater MeSH
- transplantace ledvin MeSH
- transplantace orgánů * škodlivé účinky mortalita MeSH
- transplantace plic MeSH
- transplantace srdce MeSH
- výsledek terapie MeSH
- Check Tag
- dítě MeSH
- kojenec MeSH
- lidé MeSH
- mladiství MeSH
- mužské pohlaví MeSH
- předškolní dítě MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- multicentrická studie MeSH
- Geografické názvy
- Evropa MeSH
We report data obtained from a retrospective multicenter pediatric survey on behalf of the European Society for Blood and Marrow Transplantation (EBMT). Information on solid organ transplantation (SOT) performed in pediatric recipients of either autologous or allogeneic hematopoietic stem cell transplantation (HSCT) between 1984 and 2016 was collected in 20 pediatric EBMT Centers (25.6%). Overall, we evaluated data on 44 SOTs following HSCT including 20 liver (LTx), 12 lung (LuTx), 6 heart (HTx), and 6 kidney (KTx) transplantations. The indication for SOT was organ failure related to intractable graft-vs-host disease in 16 children (36.3%), acute or chronic HSCT-related toxicity in 18 (40.9%), and organ dysfunction related to the underlying disease in 10 (22.8%). The median follow-up was 10.9 years (95% confidence interval: 1.7-29.5). The overall survival rate at 1 and 5 years after SOT was 85.7% and 80.4%, respectively: it was 74% and 63.2% after LTx, 83.2% after HTx, and 100% equally after LuTx and KTx. This multicenter survey confirms that SOT represents a promising option in children with severe organ failure occurring after HSCT. Additional studies are needed to further establish the effectiveness of SOT after HSCT and to better understand the mechanism underlying this encouraging success.
Department of Pediatric Oncology and Hematology Hospital Universitario Vall d'Hebron Barcelona Spain
Department of Pediatrics Jena University Hospital Jena Germany
Department of Pediatrics University Medical Center Ulm Germany
Department Pediatric Hematology Oncology Hemostaseology Universitätsklinikum Leipzig Leipzig Germany
European Society for Blood and Marrow Transplantation Pediatric Disease Working Party Paris France
Hematopoietic Stem Cell Transplantation Unit Hematology Oncology Istituto G Gaslini Genova Italy
Instute Portugues Oncologia Lisboa Lisboa Portugal
Pediatric Hematology and Oncology University Hospital Münster Muenster Germany
Pediatric Hematopoietic Transplant Unit Sant Pau Hospital Barcelona Spain
Service of Pediatric Hematology Oncology Hôpital Armand Trousseau Paris France
St Anna Children's Hospital Medical University of Vienna Vienna Austria
Unidad de Hematología y Oncología Pediátrica Hospital Universitario La Paz Madrid Spain
Citace poskytuje Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc20025822
- 003
- CZ-PrNML
- 005
- 20201222155453.0
- 007
- ta
- 008
- 201125s2019 xxu f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.1111/ajt.15240 $2 doi
- 035 __
- $a (PubMed)30586230
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a xxu
- 100 1_
- $a Faraci, Maura $u Hematopoietic Stem Cell Transplantation Unit, Hematology-Oncology, Istituto G Gaslini, Genova, Italy.
- 245 10
- $a Solid organ transplantation after hematopoietic stem cell transplantation in childhood: A multicentric retrospective survey / $c M. Faraci, A. Bertaina, A. Dalissier, M. Ifversen, A. Schulz, A. Gennery, B. Burkhardt, I. Badell Serra, C. Diaz-de-Heredia, E. Lanino, AC. Lankester, B. Gruhn, S. Matthes-Martin, JS. Kühl, S. Varotto, C. Paillard, A. Guilmatre, A. Sastre, M. Abecasis, B. Garwer, P. Sedlacek, JJ. Boelens, E. Beohou, P. Bader, EBMT Pediatric Disease Working Party,
- 520 9_
- $a We report data obtained from a retrospective multicenter pediatric survey on behalf of the European Society for Blood and Marrow Transplantation (EBMT). Information on solid organ transplantation (SOT) performed in pediatric recipients of either autologous or allogeneic hematopoietic stem cell transplantation (HSCT) between 1984 and 2016 was collected in 20 pediatric EBMT Centers (25.6%). Overall, we evaluated data on 44 SOTs following HSCT including 20 liver (LTx), 12 lung (LuTx), 6 heart (HTx), and 6 kidney (KTx) transplantations. The indication for SOT was organ failure related to intractable graft-vs-host disease in 16 children (36.3%), acute or chronic HSCT-related toxicity in 18 (40.9%), and organ dysfunction related to the underlying disease in 10 (22.8%). The median follow-up was 10.9 years (95% confidence interval: 1.7-29.5). The overall survival rate at 1 and 5 years after SOT was 85.7% and 80.4%, respectively: it was 74% and 63.2% after LTx, 83.2% after HTx, and 100% equally after LuTx and KTx. This multicenter survey confirms that SOT represents a promising option in children with severe organ failure occurring after HSCT. Additional studies are needed to further establish the effectiveness of SOT after HSCT and to better understand the mechanism underlying this encouraging success.
- 650 _2
- $a mladiství $7 D000293
- 650 _2
- $a alografty $7 D064591
- 650 _2
- $a autologní štěp $7 D064592
- 650 _2
- $a dítě $7 D002648
- 650 _2
- $a předškolní dítě $7 D002675
- 650 _2
- $a kohortové studie $7 D015331
- 650 _2
- $a ženské pohlaví $7 D005260
- 650 _2
- $a nemoc štěpu proti hostiteli $x etiologie $x chirurgie $7 D006086
- 650 _2
- $a transplantace srdce $7 D016027
- 650 _2
- $a transplantace hematopoetických kmenových buněk $x škodlivé účinky $7 D018380
- 650 _2
- $a lidé $7 D006801
- 650 _2
- $a kojenec $7 D007223
- 650 _2
- $a transplantace ledvin $7 D016030
- 650 _2
- $a transplantace jater $7 D016031
- 650 _2
- $a transplantace plic $7 D016040
- 650 _2
- $a mužské pohlaví $7 D008297
- 650 12
- $a transplantace orgánů $x škodlivé účinky $x mortalita $7 D016377
- 650 _2
- $a proporcionální rizikové modely $7 D016016
- 650 _2
- $a retrospektivní studie $7 D012189
- 650 _2
- $a průzkumy a dotazníky $7 D011795
- 650 _2
- $a míra přežití $7 D015996
- 650 _2
- $a výsledek terapie $7 D016896
- 651 _2
- $a Evropa $x epidemiologie $7 D005060
- 655 _2
- $a časopisecké články $7 D016428
- 655 _2
- $a multicentrická studie $7 D016448
- 700 1_
- $a Bertaina, Alice $u Dipartimento di Onco-Ematologia Pediatrica, IRCSS Ospedale Pediatrico Bambino Gesù, Rome, Italy. Division of Stem Cell Transplantation and Regenerative Medicine, Department of Pediatrics, School of Medicine, Stanford University, Stanford, California.
- 700 1_
- $a Dalissier, Arnaud $u European Society for Blood and Marrow Transplantation Pediatric Disease Working Party, Paris, France.
- 700 1_
- $a Ifversen, Marianne $u Department for Children and Adolescents, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
- 700 1_
- $a Schulz, Ansgar $u Department of Pediatrics, University Medical Center, Ulm, Germany.
- 700 1_
- $a Gennery, Andrew $u Institute of Cellular Medicine, Pediatric Immunology Department, Newcastle University, Great North Children's Hospital, Newcastle-upon-Tyne, UK.
- 700 1_
- $a Burkhardt, Birgit $u Pediatric Hematology and Oncology, University Hospital Münster, Muenster, Germany.
- 700 1_
- $a Badell Serra, Isabel $u Pediatric Hematopoietic Transplant Unit, Sant Pau Hospital, Barcelona, Spain.
- 700 1_
- $a Diaz-de-Heredia, Cristina $u Department of Pediatric Oncology and Hematology, Hospital Universitario Vall d'Hebron, Barcelona, Spain.
- 700 1_
- $a Lanino, Edoardo $u Hematopoietic Stem Cell Transplantation Unit, Hematology-Oncology, Istituto G Gaslini, Genova, Italy.
- 700 1_
- $a Lankester, Arjan C $u Department of Pediatrics Stem Cell Transplantation Program, Leiden University Medical Center, Leiden, The Netherlands.
- 700 1_
- $a Gruhn, Bernd $u Department of Pediatrics, Jena University Hospital, Jena, Germany.
- 700 1_
- $a Matthes-Martin, Susanne $u St Anna Children's Hospital, Medical University of Vienna, Vienna, Austria.
- 700 1_
- $a Kühl, Joern S $u Department Pediatric Hematology, Oncology, Hemostaseology, Universitätsklinikum Leipzig, Leipzig, Germany.
- 700 1_
- $a Varotto, Stefania $u Clinic of Pediatric Hemato-Oncology, Department of Women's and Children's Health, University Hospital of Padova, Padova, Italy.
- 700 1_
- $a Paillard, Catherine $u Hematology, Oncology and Stem Cell Transplantation, Department of Pediatrics, Hôpital Hautepierre, Strasbourg, France.
- 700 1_
- $a Guilmatre, Audrey $u Service of Pediatric Hematology-Oncology, Hôpital Armand Trousseau, Paris, France.
- 700 1_
- $a Sastre, Ana $u Unidad de Hematología y Oncología Pediátrica, Hospital Universitario La Paz, Madrid, Spain.
- 700 1_
- $a Abecasis, Manuel $u Instute Portugues Oncologia Lisboa, Lisboa, Portugal.
- 700 1_
- $a Garwer, Birgit $u University Hospital Eppendorf, Hamburg, Germany.
- 700 1_
- $a Sedlacek, Petr $u University Hospital Motol, Prague, Czech Republic.
- 700 1_
- $a Boelens, Jaap J $u Pediatric Blood and Marrow Transplantation Program, Laboratory for Translational Immunology Tumor-immunology, University Medical Center, Utrecht, The Netherlands. Stem Cell Transplant and Cellular Therapies Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York.
- 700 1_
- $a Beohou, Eric $u European Society for Blood and Marrow Transplantation Pediatric Disease Working Party, Paris, France.
- 700 1_
- $a Bader, Peter $u Department for Children and Adolescents, Division for Stem Cell Transplantation and Immunology, University Hospital Frankfurt, Frankfurt am Main, Germany.
- 710 2_
- $a EBMT Pediatric Disease Working Party
- 773 0_
- $w MED00006447 $t American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons $x 1600-6143 $g Roč. 19, č. 6 (2019), s. 1798-1805
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/30586230 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y a $z 0
- 990 __
- $a 20201125 $b ABA008
- 991 __
- $a 20201222155448 $b ABA008
- 999 __
- $a ok $b bmc $g 1599967 $s 1116508
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2019 $b 19 $c 6 $d 1798-1805 $e 20190125 $i 1600-6143 $m American journal of transplantation $n Am J Transplant $x MED00006447
- LZP __
- $a Pubmed-20201125
