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Cardiac arrest in takotsubo syndrome: results from the InterTAK Registry
S. Gili, VL. Cammann, SA. Schlossbauer, K. Kato, F. D'Ascenzo, D. Di Vece, S. Jurisic, J. Micek, S. Obeid, B. Bacchi, KA. Szawan, F. Famos, A. Sarcon, R. Levinson, KJ. Ding, B. Seifert, O. Lenoir, E. Bossone, R. Citro, J. Franke, LC. Napp, M....
Jazyk angličtina Země Velká Británie
Typ dokumentu časopisecké články, multicentrická studie, práce podpořená grantem
NLK
Free Medical Journals
od 1996 do Před 1 rokem
Open Access Digital Library
od 1996-01-01
PubMed
31098611
DOI
10.1093/eurheartj/ehz170
Knihovny.cz E-zdroje
- MeSH
- analýza přežití MeSH
- lidé středního věku MeSH
- lidé MeSH
- prognóza MeSH
- registrace MeSH
- retrospektivní studie MeSH
- srdeční zástava diagnóza epidemiologie etiologie mortalita MeSH
- takotsubo kardiomyopatie komplikace MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- multicentrická studie MeSH
- práce podpořená grantem MeSH
AIMS: We aimed to evaluate the frequency, clinical features, and prognostic implications of cardiac arrest (CA) in takotsubo syndrome (TTS). METHODS AND RESULTS: We reviewed the records of patients with CA and known heart rhythm from the International Takotsubo Registry. The main outcomes were 60-day and 5-year mortality. In addition, predictors of mortality and predictors of CA during the acute TTS phase were assessed. Of 2098 patients, 103 patients with CA and known heart rhythm during CA were included. Compared with patients without CA, CA patients were more likely to be younger, male, and have apical TTS, atrial fibrillation (AF), neurologic comorbidities, physical triggers, and longer corrected QT-interval and lower left ventricular ejection fraction on admission. In all, 57.1% of patients with CA at admission had ventricular fibrillation/tachycardia, while 73.7% of patients with CA in the acute phase had asystole/pulseless electrical activity. Patients with CA showed higher 60-day (40.3% vs. 4.0%, P < 0.001) and 5-year mortality (68.9% vs. 16.7%, P < 0.001) than patients without CA. T-wave inversion and intracranial haemorrhage were independently associated with higher 60-day mortality after CA, whereas female gender was associated with lower 60-day mortality. In the acute phase, CA occurred less frequently in females and more frequently in patients with AF, ST-segment elevation, and higher C-reactive protein on admission. CONCLUSIONS: Cardiac arrest is relatively frequent in TTS and is associated with higher short- and long-term mortality. Clinical and electrocardiographic parameters independently predicted mortality after CA.
1st Department of Cardiology Medical University of Gdansk Gdansk Poland
Center for Cardiology Cardiology 1 University Medical Center Mainz Mainz Germany
Clinic for Cardiology and Pneumology Georg August University Goettingen Goettingen Germany
Department of Cardiology and Angiology Hannover Medical School Hannover Germany
Department of Cardiology and Cardiac Imaging Center University Hospital of Rangueil Toulouse France
Department of Cardiology Charité Campus Rudolf Virchow Berlin Germany
Department of Cardiology Heidelberg University Hospital Heidelberg Germany
Department of Cardiology John Radcliffe Hospital Oxford University Hospitals Oxford UK
Department of Cardiology Kantonsspital Lucerne Lucerne Switzerland
Department of Cardiology Kantonsspital Winterthur Winterthur Switzerland
Department of Cardiology Kings College Hospital Kings Health Partners London UK
Department of Cardiology Leiden University Medical Centre Leiden The Netherlands
Department of Cardiology Medical University of Warsaw Warsaw Poland
Department of Cardiology University Heart Center University Hospital Zurich Switzerland
Department of Cardiology University Hospital Basel Basel Switzerland
Department of Cardiovascular Diseases Mayo Clinic Rochester MN USA
Department of Cardiovascular Sciences Catholic University of the Sacred Heart Rome Rome Italy
Department of General and Interventional Cardiology University Heart Center Hamburg Hamburg Germany
Department of Internal Medicine 2 Cardiology University of Ulm Medical Center Ulm Germany
Department of Internal Medicine 3 Heart Center University of Cologne Cologne Germany
Department of Internal Medicine Cardiology University of Leipzig Heart Center Leipzig Germany
Department of Medicine College of Medicine University of Florida Gainesville FL USA
Discipline of Medicine Queen Elizabeth Hospital University of Adelaide Adelaide Australia
Division of Cardiology 'Antonio Cardarelli' Hospital Naples Italy
FB Mathematics and Computer Science University of Bremen Bremen Germany
Heart and Vascular Centre Bad Bevensen Bad Bevensen Germany
Heart Center Turku University Hospital and University of Turku Turku Finland
Heart Department University Hospital 'San Giovanni di Dio e Ruggi d'Aragona' Salerno Italy
Intensive coronary care Unit Moscow City Hospital 1 named after N Pirogov Moscow Russia
Internal Medicine Cardiology Angiology and Pneumology Magdeburg University Magdeburg Germany
Keck School of Medicine University of Southern California Los Angeles CA USA
Klinik für Innere Medizin 3 Universitätsklinikum des Saarlandes Homburg Saar Germany
Krankenhaus 'Maria Hilf' Medizinische Klinik Stadtlohn Germany
Structural Interventional Cardiology University Hospital Careggi Florence Italy
TJ Health Partners Heart and Vascular Glasgow KY USA
University Hospital for Internal Medicine 3 Medical University Innsbruck Innsbruck Austria
Citace poskytuje Crossref.org
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- $a Gili, Sebastiano $u Department of Cardiology, University Heart Center, University Hospital Zurich, Switzerland. Division of Cardiology, Department of Medical Sciences, AOU Citta della Salute e della Scienza, University of Turin, Turin, Italy.
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- $a Cardiac arrest in takotsubo syndrome: results from the InterTAK Registry / $c S. Gili, VL. Cammann, SA. Schlossbauer, K. Kato, F. D'Ascenzo, D. Di Vece, S. Jurisic, J. Micek, S. Obeid, B. Bacchi, KA. Szawan, F. Famos, A. Sarcon, R. Levinson, KJ. Ding, B. Seifert, O. Lenoir, E. Bossone, R. Citro, J. Franke, LC. Napp, M. Jaguszewski, M. Noutsias, T. Münzel, M. Knorr, S. Heiner, HA. Katus, C. Burgdorf, H. Schunkert, H. Thiele, J. Bauersachs, C. Tschöpe, BM. Pieske, L. Rajan, G. Michels, R. Pfister, A. Cuneo, C. Jacobshagen, G. Hasenfuß, M. Karakas, W. Koenig, W. Rottbauer, SM. Said, RC. Braun-Dullaeus, A. Banning, F. Cuculi, R. Kobza, TA. Fischer, T. Vasankari, KEJ. Airaksinen, G. Opolski, R. Dworakowski, P. MacCarthy, C. Kaiser, S. Osswald, L. Galiuto, F. Crea, W. Dichtl, K. Empen, SB. Felix, C. Delmas, O. Lairez, I. El-Battrawy, I. Akin, M. Borggrefe, E. Gilyarova, A. Shilova, M. Gilyarov, JD. Horowitz, M. Kozel, P. Tousek, P. Widimský, DE. Winchester, C. Ukena, F. Gaita, C. Di Mario, MB. Wischnewsky, JJ. Bax, A. Prasad, M. Böhm, F. Ruschitzka, TF. Lüscher, JR. Ghadri, C. Templin,
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- $a AIMS: We aimed to evaluate the frequency, clinical features, and prognostic implications of cardiac arrest (CA) in takotsubo syndrome (TTS). METHODS AND RESULTS: We reviewed the records of patients with CA and known heart rhythm from the International Takotsubo Registry. The main outcomes were 60-day and 5-year mortality. In addition, predictors of mortality and predictors of CA during the acute TTS phase were assessed. Of 2098 patients, 103 patients with CA and known heart rhythm during CA were included. Compared with patients without CA, CA patients were more likely to be younger, male, and have apical TTS, atrial fibrillation (AF), neurologic comorbidities, physical triggers, and longer corrected QT-interval and lower left ventricular ejection fraction on admission. In all, 57.1% of patients with CA at admission had ventricular fibrillation/tachycardia, while 73.7% of patients with CA in the acute phase had asystole/pulseless electrical activity. Patients with CA showed higher 60-day (40.3% vs. 4.0%, P < 0.001) and 5-year mortality (68.9% vs. 16.7%, P < 0.001) than patients without CA. T-wave inversion and intracranial haemorrhage were independently associated with higher 60-day mortality after CA, whereas female gender was associated with lower 60-day mortality. In the acute phase, CA occurred less frequently in females and more frequently in patients with AF, ST-segment elevation, and higher C-reactive protein on admission. CONCLUSIONS: Cardiac arrest is relatively frequent in TTS and is associated with higher short- and long-term mortality. Clinical and electrocardiographic parameters independently predicted mortality after CA.
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