• Something wrong with this record ?

Cardiac papillary fibroelastomas: A 10-year single-center surgical experience and long-term echocardiographic follow-up study

M. Kolek, J. Dvorackova, O. Motyka, R. Brat

. 2020 ; 164 (1) : 84-91. [pub] 20191118

Language English Country Czech Republic

Document type Journal Article

Persistent link   https://www.medvik.cz/link/bmc21006940

AIMS: Limited contemporary data are available on the clinical and echocardiographic outcomes after surgery for cardiac papillary fibroelastoma (CPF). The aim of this study was to review the clinical manifestations, pathological characteristics, surgical management, and prognoses of patients with histologically verified CPF, who underwent surgery at our cardiac surgery center from 2008 to 2018. METHODS AND RESULTS: Twelve patients of median age 62 years (28 to 77 years) were treated. Embolic stroke or transient ischemic attack (five patients, 42%) were the only CPF clinical manifestations. Eleven (92%) tumors were localized on the valves, with the aortic valve being the most common tumor site (seven patients; 58%). Multiple factor analysis revealed no independent predictor of CPF-related embolization. Simple shave tumor excision was sufficient in most patients (10 patients, 83%). No operative or tumor-related late mortality during the median follow-up period of 4.7 years (1.1 to 10.2 years) was recorded. Asymptomatic metachronous valve tumor recurrence (in a location different from that of the original tumor) was revealed in two patients (17%) by transesophageal echocardiography (TEE), not detected by transthoracic echocardiography (TTE). One of these two patients underwent repeated surgery for CPF but later suffered a recurrent embolic stroke, due to another tumor recurrence. CONCLUSION: CPF can be safely and effectively treated surgically. TEE is superior to the TTE option in CPF post-operative recurrence detection. There is a clear need for a prospective study to determine criteria for embolization risk stratification and optimum management in patients with CPF.

References provided by Crossref.org

Bibliography, etc.

Literatura

000      
00000naa a2200000 a 4500
001      
bmc21006940
003      
CZ-PrNML
005      
20210503123843.0
007      
ta
008      
210309s2020 xr ad f 000 0|eng||
009      
AR
024    7_
$a 10.5507/bp.2019.053 $2 doi
035    __
$a (PubMed)31748759
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xr
100    1_
$a Kolek, Martin $7 xx0224231 $u Department of Clinic Subjects, Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic; Department of Cardiac Surgery, University Hospital Ostrava, Ostrava, Czech Republic
245    10
$a Cardiac papillary fibroelastomas: A 10-year single-center surgical experience and long-term echocardiographic follow-up study / $c M. Kolek, J. Dvorackova, O. Motyka, R. Brat
504    __
$a Literatura
520    9_
$a AIMS: Limited contemporary data are available on the clinical and echocardiographic outcomes after surgery for cardiac papillary fibroelastoma (CPF). The aim of this study was to review the clinical manifestations, pathological characteristics, surgical management, and prognoses of patients with histologically verified CPF, who underwent surgery at our cardiac surgery center from 2008 to 2018. METHODS AND RESULTS: Twelve patients of median age 62 years (28 to 77 years) were treated. Embolic stroke or transient ischemic attack (five patients, 42%) were the only CPF clinical manifestations. Eleven (92%) tumors were localized on the valves, with the aortic valve being the most common tumor site (seven patients; 58%). Multiple factor analysis revealed no independent predictor of CPF-related embolization. Simple shave tumor excision was sufficient in most patients (10 patients, 83%). No operative or tumor-related late mortality during the median follow-up period of 4.7 years (1.1 to 10.2 years) was recorded. Asymptomatic metachronous valve tumor recurrence (in a location different from that of the original tumor) was revealed in two patients (17%) by transesophageal echocardiography (TEE), not detected by transthoracic echocardiography (TTE). One of these two patients underwent repeated surgery for CPF but later suffered a recurrent embolic stroke, due to another tumor recurrence. CONCLUSION: CPF can be safely and effectively treated surgically. TEE is superior to the TTE option in CPF post-operative recurrence detection. There is a clear need for a prospective study to determine criteria for embolization risk stratification and optimum management in patients with CPF.
650    _2
$a dospělí $7 D000328
650    _2
$a senioři $7 D000368
650    _2
$a papilární fibroelastom srdce $x diagnóza $x mortalita $x chirurgie $7 D000084122
650    _2
$a echokardiografie transezofageální $7 D017548
650    _2
$a ženské pohlaví $7 D005260
650    _2
$a následné studie $7 D005500
650    _2
$a lidé $7 D006801
650    _2
$a mužské pohlaví $7 D008297
650    _2
$a lidé středního věku $7 D008875
650    _2
$a retrospektivní studie $7 D012189
650    _2
$a míra přežití $7 D015996
650    _2
$a výsledek terapie $7 D016896
651    _2
$a Česká republika $7 D018153
655    _2
$a časopisecké články $7 D016428
700    1_
$a Dvořáčková, Jana, $d 1956- $7 xx0077620 $u Institute of Pathology, Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic
700    1_
$a Motyka, Oldřich $7 xx0228211 $u Nanotechnology centre, VSB - Technical University of Ostrava, Ostrava, Czech Republic; ENET centre, VSB - Technical University of Ostrava, Ostrava, Czech Republic
700    1_
$a Brát, Radim, $d 1962- $7 xx0080425 $u Department of Cardiac Surgery, University Hospital Ostrava, Ostrava, Czech Republic; Department of Surgical Studies, Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic
773    0_
$w MED00012606 $t Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia $x 1213-8118 $g Roč. 164, č. 1 (2020), s. 84-91
856    41
$u https://pubmed.ncbi.nlm.nih.gov/31748759 $y Pubmed
910    __
$a ABA008 $b A 1502 $c 958 $y p $z 0
990    __
$a 20210309 $b ABA008
991    __
$a 20210408192530 $b ABA008
999    __
$a ok $b bmc $g 1648162 $s 1127278
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2020 $b 164 $c 1 $d 84-91 $e 20191118 $i 1213-8118 $m Biomedical papers of the Medical Faculty of the University Palacký, Olomouc Czech Republic $n Biomed. Pap. Fac. Med. Palacký Univ. Olomouc Czech Repub. (Print) $x MED00012606
LZP    __
$b NLK118 $a Pubmed-20210309

Find record

Citation metrics

Archiving options