• Je něco špatně v tomto záznamu ?

Heart rate as an independent predictor of long term mortality of acute heart failure patients in sinus rhythm according to their ejection fraction: data from the AHEAD registry

J. Jarkovsky, J. Spinar, B. Tyl, F. Fougerousse, J. Vitovec, A. Linhart, P. Widimsky, R. Miklik, L. Spinarova, J. Belohlavek, F. Malek, M. Felsoci, J. Kettner, P. Ostadal, J. Vaclavik, L. Dusek, P. Lokaj, A. Mebazaa, A. Cohen Solal, J. Parenica,...

. 2020 ; 78 (-) : 88-94. [pub] 20200418

Jazyk angličtina Země Nizozemsko

Typ dokumentu časopisecké články, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/bmc21012306

BACKGROUND: Heart rate (HR) at admission in patients with acute heart failure (AHF) has been shown to be an important risk marker of in-hospital mortality. However, its relation with mid and long-term prognosis as well as the impact of Ejection Fraction (EF) is unknown. Our objective was to study the relationship between long-term survival and HR at admission depending on EF in a cohort of patients hospitalized for AHF. METHODS: We analyzed the data of 2335 patients in sinus rhythm hospitalized for AHF from AHEAD registry. Patients with cardiogenic shock and AHF from surgical or non-cardiac etiology were excluded. RESULTS: Survival rates at 6 and 12 months were 84.8% and 78% respectively. Increased age, decreased diastolic BP, lack of PCI during hospitalization, increased creatinine level and increased HR (with different cut-offs according to EF categories) were found as predictors whatever the EF at 6 and 12 months. Optimal prognostic cut-offs of heart rate were identified for Heart Failure with reduced EF at 100 bpm, for Heart Failure with mid-range EF at 90 bpm and for Heart Failure with preserved EF at 80 bpm for both 6 and 12 months. CONCLUSION: Our study suggests that HR at admission appears to be an independent prognostic parameter in AHF patients in sinus rhythm irrespective of EF and can be used to classify patients according to the severity of the disease.

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc21012306
003      
CZ-PrNML
005      
20210507102151.0
007      
ta
008      
210420s2020 ne f 000 0|eng||
009      
AR
024    7_
$a 10.1016/j.ejim.2020.04.022 $2 doi
035    __
$a (PubMed)32312619
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a ne
100    1_
$a Jarkovsky, Jiri $u Institute of Biostatistics and Analyses, Faculty of Medicine, Masaryk University, Brno, Czech Republic; Department of Cardiology, Na Homolce Hospital, Prague, Czech Republic
245    10
$a Heart rate as an independent predictor of long term mortality of acute heart failure patients in sinus rhythm according to their ejection fraction: data from the AHEAD registry / $c J. Jarkovsky, J. Spinar, B. Tyl, F. Fougerousse, J. Vitovec, A. Linhart, P. Widimsky, R. Miklik, L. Spinarova, J. Belohlavek, F. Malek, M. Felsoci, J. Kettner, P. Ostadal, J. Vaclavik, L. Dusek, P. Lokaj, A. Mebazaa, A. Cohen Solal, J. Parenica, AHEAD group-authors
520    9_
$a BACKGROUND: Heart rate (HR) at admission in patients with acute heart failure (AHF) has been shown to be an important risk marker of in-hospital mortality. However, its relation with mid and long-term prognosis as well as the impact of Ejection Fraction (EF) is unknown. Our objective was to study the relationship between long-term survival and HR at admission depending on EF in a cohort of patients hospitalized for AHF. METHODS: We analyzed the data of 2335 patients in sinus rhythm hospitalized for AHF from AHEAD registry. Patients with cardiogenic shock and AHF from surgical or non-cardiac etiology were excluded. RESULTS: Survival rates at 6 and 12 months were 84.8% and 78% respectively. Increased age, decreased diastolic BP, lack of PCI during hospitalization, increased creatinine level and increased HR (with different cut-offs according to EF categories) were found as predictors whatever the EF at 6 and 12 months. Optimal prognostic cut-offs of heart rate were identified for Heart Failure with reduced EF at 100 bpm, for Heart Failure with mid-range EF at 90 bpm and for Heart Failure with preserved EF at 80 bpm for both 6 and 12 months. CONCLUSION: Our study suggests that HR at admission appears to be an independent prognostic parameter in AHF patients in sinus rhythm irrespective of EF and can be used to classify patients according to the severity of the disease.
650    12
$a srdeční selhání $7 D006333
650    _2
$a srdeční frekvence $7 D006339
650    _2
$a mortalita v nemocnicích $7 D017052
650    _2
$a hospitalizace $7 D006760
650    _2
$a lidé $7 D006801
650    _2
$a kojenec $7 D007223
650    12
$a koronární angioplastika $7 D062645
650    _2
$a prognóza $7 D011379
650    _2
$a registrace $7 D012042
650    _2
$a tepový objem $7 D013318
655    _2
$a časopisecké články $7 D016428
655    _2
$a práce podpořená grantem $7 D013485
700    1_
$a Spinar, Jindrich $u Department of Cardiology, University Hospital Brno, Brno, Czech Republic; Medical Faculty, Masaryk University, Brno, Czech Republic; Department of Cardiology, Na Homolce Hospital, Prague, Czech Republic
700    1_
$a Tyl, Benoit $u Department of Cardiovascular Translational and Clinical Research, Institut de Recherches Internationales Servier (IRIS), France; Department of Cardiology, Na Homolce Hospital, Prague, Czech Republic
700    1_
$a Fougerousse, Françoise $u Department of Cardiovascular Translational and Clinical Research, Institut de Recherches Internationales Servier (IRIS), France; Department of Cardiology, Na Homolce Hospital, Prague, Czech Republic
700    1_
$a Vitovec, Jiri $u Medical Faculty, Masaryk University, Brno, Czech Republic; First Department of Cardiovascular Internal Medicine, University Hospital St Anne's, Brno, Czech Republic; Department of Cardiology, Na Homolce Hospital, Prague, Czech Republic
700    1_
$a Linhart, Ales $u 2nd Department of Cardiovascular Internal Medicine, First Medical Faculty, Charles University, Prague and General Teaching Hospital of Prague, Prague, Czech Republic; Department of Cardiology, Na Homolce Hospital, Prague, Czech Republic
700    1_
$a Widimsky, Petr $u University Hospital Kralovske Vinohrady and the Third Faculty of Medicine, Charles University, Prague, Czech Republic; Department of Cardiology, Na Homolce Hospital, Prague, Czech Republic
700    1_
$a Miklik, Roman $u Cardiology Department, University Hospital Plzen, Plzen, Czech Republic; Cardiology Department, Hospital Podlesi, Trinec, Czech Republic; Department of Cardiology, Na Homolce Hospital, Prague, Czech Republic
700    1_
$a Spinarova, Lenka $u Medical Faculty, Masaryk University, Brno, Czech Republic; First Department of Cardiovascular Internal Medicine, University Hospital St Anne's, Brno, Czech Republic; Department of Cardiology, Na Homolce Hospital, Prague, Czech Republic
700    1_
$a Belohlavek, Jan $u 2nd Department of Cardiovascular Internal Medicine, First Medical Faculty, Charles University, Prague and General Teaching Hospital of Prague, Prague, Czech Republic; Department of Cardiology, Na Homolce Hospital, Prague, Czech Republic
700    1_
$a Malek, Filip $u Department of Cardiology, Institute of Clinical and Experimental Medicine, Prague, Czech Republic; Department of Cardiology, Na Homolce Hospital, Prague, Czech Republic
700    1_
$a Felsoci, Marian $u Department of Cardiology, University Hospital Brno, Brno, Czech Republic; Medical Faculty, Masaryk University, Brno, Czech Republic; Department of Cardiology, Na Homolce Hospital, Prague, Czech Republic
700    1_
$a Kettner, Jiri $u Department of Cardiology, Na Homolce Hospital, Prague, Czech Republic; Department of Internal Medicine, University Hospital Olomouc, Olomouc, Czech Republic
700    1_
$a Ostadal, Petr $u Department of Cardiology, Na Homolce Hospital, Prague, Czech Republic; Department of Cardiology, Institute of Clinical and Experimental Medicine, Prague, Czech Republic
700    1_
$a Vaclavik, Jan $u Department of Cardiology, Na Homolce Hospital, Prague, Czech Republic; Université Paris Diderot, PRES Sorbonne Paris Cité, France
700    1_
$a Dusek, Ladislav $u Institute of Biostatistics and Analyses, Faculty of Medicine, Masaryk University, Brno, Czech Republic; Department of Cardiology, Na Homolce Hospital, Prague, Czech Republic
700    1_
$a Lokaj, Petr $u Department of Cardiology, University Hospital Brno, Brno, Czech Republic; Medical Faculty, Masaryk University, Brno, Czech Republic; Department of Cardiology, Na Homolce Hospital, Prague, Czech Republic
700    1_
$a Mebazaa, Alexandre $u Department of Cardiology, Na Homolce Hospital, Prague, Czech Republic; Department of Anaesthesiology and Critical Care and Burn unit, APHP, Saint Louis Lariboisière University Hospitals, Paris, France; U 942 INSERM, Paris, France; Cardiology Department, Lariboisière University Hospitals, Paris, France
700    1_
$a Cohen Solal, Alain $u Department of Cardiology, Na Homolce Hospital, Prague, Czech Republic; Department of Anaesthesiology and Critical Care and Burn unit, APHP, Saint Louis Lariboisière University Hospitals, Paris, France; Cardiology Department, Lariboisière University Hospitals, Paris, France
700    1_
$a Parenica, Jiri $u Department of Cardiology, University Hospital Brno, Brno, Czech Republic; Medical Faculty, Masaryk University, Brno, Czech Republic; Department of Cardiology, Na Homolce Hospital, Prague, Czech Republic. Electronic address: jiri.parenica@atlas.cz
710    2_
$a AHEAD group-authors
773    0_
$w MED00001627 $t European journal of internal medicine $x 1879-0828 $g Roč. 78, č. - (2020), s. 88-94
856    41
$u https://pubmed.ncbi.nlm.nih.gov/32312619 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y p $z 0
990    __
$a 20210420 $b ABA008
991    __
$a 20210507102150 $b ABA008
999    __
$a ok $b bmc $g 1650635 $s 1132685
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2020 $b 78 $c - $d 88-94 $e 20200418 $i 1879-0828 $m European journal of internal medicine $n Eur J Intern Med $x MED00001627
LZP    __
$a Pubmed-20210420

Najít záznam

Citační ukazatele

Možnosti archivace