• Something wrong with this record ?

Psoas density - an optimal sarcopaenic indicator associated with postoperative complications after colorectal resection for cancer

A. Pekařová, M. Pekař, M. Soltes, L. Havrlentová, T. Chovancová

. 2021 ; 16 (1) : 91-97. [pub] 20201113

Language English Country Poland

Document type Journal Article

Persistent link   https://www.medvik.cz/link/bmc21018245

Introduction: Sarcopaenia seems to be predictive factor for postoperative morbidity and mortality after colorectal resection for cancer. Nevertheless, an ideal sarcopaenic indicator is still to be identified. Aim: To evaluate computed tomography (CT) measured total abdominal muscle area (TAMA), total psoas muscle area (TPA), and psoas density (PD) - previously described sarcopaenia indicators - as possible risk factors for postoperative complications in patients after curative colon and rectal resections for colorectal cancer. Material and methods: Consecutive patients after elective curative colon or rectal resection for cancer at a single institution were divided into cohorts with uncomplicated postoperative course or complications Clavien-Dindo grade I-II (Cl-Di 0-II) and complications Clavien-Dindo grade III-V (Cl-Di III-V). Cohorts were statistically tested for significant differences in TAMA, TPA, and PD calculated from preoperative staging CT scans at the level of the third lumbar vertebra. Results: Data of 112 patients were analysed from a prospectively run database; 65 underwent colon and 47 rectal resections. PD was significantly higher in the Cl-Di 0-II cohort compared to the Cl-Di III-V for both colon (42.67 ±6.52 vs. 40.11 ±7.57 HU, p = 0.002) and rectal resections (44.08 ±5.86 vs. 43.03 ±5.70HU, p = 0.016). TAMA and TPA failed to show significant differences. Conclusions: Psoas density is significantly decreased in patients with Clavien-Dindo grade III-V complications after curative resection for colon and rectal cancer. Due to the simplicity and affordability of its assessment from preoperative staging CT scan, it might be considered an optimal sarcopaenic indicator to be utilised in everyday practice.

References provided by Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc21018245
003      
CZ-PrNML
005      
20210729103945.0
007      
ta
008      
210726s2021 pl f 000 0|eng||
009      
AR
024    7_
$a 10.5114/wiitm.2020.100880 $2 doi
035    __
$a (PubMed)33786121
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a pl
100    1_
$a Pekařová, Anna $u Department of Physiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic $u Lung Disease Department, Faculty Hospital, Ostrava, Czech Republic
245    10
$a Psoas density - an optimal sarcopaenic indicator associated with postoperative complications after colorectal resection for cancer / $c A. Pekařová, M. Pekař, M. Soltes, L. Havrlentová, T. Chovancová
520    9_
$a Introduction: Sarcopaenia seems to be predictive factor for postoperative morbidity and mortality after colorectal resection for cancer. Nevertheless, an ideal sarcopaenic indicator is still to be identified. Aim: To evaluate computed tomography (CT) measured total abdominal muscle area (TAMA), total psoas muscle area (TPA), and psoas density (PD) - previously described sarcopaenia indicators - as possible risk factors for postoperative complications in patients after curative colon and rectal resections for colorectal cancer. Material and methods: Consecutive patients after elective curative colon or rectal resection for cancer at a single institution were divided into cohorts with uncomplicated postoperative course or complications Clavien-Dindo grade I-II (Cl-Di 0-II) and complications Clavien-Dindo grade III-V (Cl-Di III-V). Cohorts were statistically tested for significant differences in TAMA, TPA, and PD calculated from preoperative staging CT scans at the level of the third lumbar vertebra. Results: Data of 112 patients were analysed from a prospectively run database; 65 underwent colon and 47 rectal resections. PD was significantly higher in the Cl-Di 0-II cohort compared to the Cl-Di III-V for both colon (42.67 ±6.52 vs. 40.11 ±7.57 HU, p = 0.002) and rectal resections (44.08 ±5.86 vs. 43.03 ±5.70HU, p = 0.016). TAMA and TPA failed to show significant differences. Conclusions: Psoas density is significantly decreased in patients with Clavien-Dindo grade III-V complications after curative resection for colon and rectal cancer. Due to the simplicity and affordability of its assessment from preoperative staging CT scan, it might be considered an optimal sarcopaenic indicator to be utilised in everyday practice.
655    _2
$a časopisecké články $7 D016428
700    1_
$a Pekař, Matej $u Department of Physiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic $u Department of Surgery, Vitkovice Hospital, Ostrava, Czech Republic
700    1_
$a Soltes, Marek $u 1 Department of Surgery, University of Pavol Jozef Safarik, Kosice, Slovak Republic
700    1_
$a Havrlentová, Lucia $u Department of Surgery, Vitkovice Hospital, Ostrava, Czech Republic
700    1_
$a Chovancová, Tereza $u Department of Surgery, Vitkovice Hospital, Ostrava, Czech Republic $u Department of Surgery, Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic
773    0_
$w MED00176919 $t Wideochirurgia i inne techniki maloinwazyjne Videosurgery and other miniinvasive techniques $x 1895-4588 $g Roč. 16, č. 1 (2021), s. 91-97
856    41
$u https://pubmed.ncbi.nlm.nih.gov/33786121 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y - $z 0
990    __
$a 20210726 $b ABA008
991    __
$a 20210729103944 $b ABA008
999    __
$a ind $b bmc $g 1676589 $s 1138689
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2021 $b 16 $c 1 $d 91-97 $e 20201113 $i 1895-4588 $m Wideochirurgia i Inne Techniki Mało Inwazyjne $n Wideochir. Inne Tech. Mało Inwazyjne $x MED00176919
LZP    __
$a Pubmed-20210726

Find record

Citation metrics

Archiving options