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Influence of central and peripheral dentin on micro-tensile bond strength estimated using a competing risk model

A. Tichy, M. Brabec, P. Bradna, K. Hosaka, A. Chiba, J. Tagami

. 2021 ; 115 (-) : 104295. [pub] 20201226

Jazyk angličtina Země Nizozemsko

Typ dokumentu časopisecké články, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/bmc21019152

The bonding performance of dental adhesives is most frequently evaluated using the micro-tensile bond strength (μTBS) test. Despite lacking evidence, peripheral specimens are often discarded to avoid regional variability. This study, therefore, examined whether μTBS to central and peripheral dentin differed. Dentin surfaces of extracted human molars were bonded with various self-etch adhesives, built up with a resin composite, cut into beams, and stressed in tension. Failure mode was classified as adhesive, cohesive in dentin, or other using scanning electron microscopy. Since cohesive failures in dentin were frequent and could confound μTBS results, the data from central/peripheral dentin were analyzed using a Weibull competing risk (CR) model distinguishing failure modes, and its outcomes were compared to a conventional failure mode non-distinguishing Weibull model. Based on the strength data of cohesively failed specimens, the CR model also estimated the strength of dentin. For comparison, the ultimate tensile strength (UTS) of dentin was measured in both regions. The conventional model suggested that peripheral μTBS was higher than central μTBS. Conversely, the CR model disclosed no significant difference in μTBS between the regions but indicated a higher strength of peripheral dentin. This finding was confirmed by UTS measurements, and further supported by the significantly higher incidence of cohesive failures in central dentin. Therefore, peripheral specimens can be used in the μTBS test as well as central ones, but a CR model should be used for statistical analysis if cohesive failures in dentin are frequent, as the strength of peripheral dentin is higher.

Citace poskytuje Crossref.org

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$a Tichy, Antonin $u Institute of Dental Medicine, First Faculty of Medicine of the Charles University and General University Hospital in Prague, Karlovo Namesti 32, Prague, 121 11, Czech Republic; Department of Cariology and Operative Dentistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan. Electronic address: antonin.tichy@lf1.cuni.cz
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$a The bonding performance of dental adhesives is most frequently evaluated using the micro-tensile bond strength (μTBS) test. Despite lacking evidence, peripheral specimens are often discarded to avoid regional variability. This study, therefore, examined whether μTBS to central and peripheral dentin differed. Dentin surfaces of extracted human molars were bonded with various self-etch adhesives, built up with a resin composite, cut into beams, and stressed in tension. Failure mode was classified as adhesive, cohesive in dentin, or other using scanning electron microscopy. Since cohesive failures in dentin were frequent and could confound μTBS results, the data from central/peripheral dentin were analyzed using a Weibull competing risk (CR) model distinguishing failure modes, and its outcomes were compared to a conventional failure mode non-distinguishing Weibull model. Based on the strength data of cohesively failed specimens, the CR model also estimated the strength of dentin. For comparison, the ultimate tensile strength (UTS) of dentin was measured in both regions. The conventional model suggested that peripheral μTBS was higher than central μTBS. Conversely, the CR model disclosed no significant difference in μTBS between the regions but indicated a higher strength of peripheral dentin. This finding was confirmed by UTS measurements, and further supported by the significantly higher incidence of cohesive failures in central dentin. Therefore, peripheral specimens can be used in the μTBS test as well as central ones, but a CR model should be used for statistical analysis if cohesive failures in dentin are frequent, as the strength of peripheral dentin is higher.
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