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Failure properties of abdominal aortic aneurysm tissue are orientation dependent
S. Polzer, V. Man, R. Vlachovský, L. Kubíček, J. Kracík, R. Staffa, T. Novotný, J. Burša, ML. Raghavan
Jazyk angličtina Země Nizozemsko
Typ dokumentu časopisecké články, práce podpořená grantem
- MeSH
- aneurysma břišní aorty * MeSH
- anizotropie MeSH
- biomechanika MeSH
- hodnocení rizik MeSH
- lidé MeSH
- mechanický stres MeSH
- ruptura aorty * MeSH
- Check Tag
- lidé MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
INTRODUCTION: Biomechanical rupture risk assessment of abdominal aortic aneurysm (AAA) requires information about failure properties of aneurysmal tissue. There are large differences between reported values. Among others, studies vary in using either axially or circumferentially oriented samples. This study investigates the effect of sample orientation on failure properties. METHODS: Aneurysmal tissues from 45 patients (11 females) were harvested during open AAA repair, cut into uniaxial samples (90) and tested mechanically within 3 h. If possible, the samples were cut in both axial (49 samples) and circumferential (41 samples) directions. Wall thickness, First Piola-Kirchhoff strength Pult and ultimate tension Tult were recorded. Influence of sample orientation and other clinical parameters were investigated using non parametric tests. RESULTS: Medians of Pult (values 1100 kPa for circumferential vs. 715 kPa for axial direction, p < 10-4) and Tult (17.4 N/cm in circumferential vs. 11.2 N/cm in axial direction, p < 10-4) were significantly higher in circumferential direction. For paired data, the median of difference was 411 kPa (p < 10-3) in Pult and 7.4 N/cm (p < 10-4) in Tult in favor of circumferential direction. CONCLUSIONS: In this first study of anisotropy in AAA wall failure properties using paired comparisons, the strength in circumferential orientation was found to be higher than in axial orientation.
Citace poskytuje Crossref.org
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- $a Polzer, Stanislav $u Department of Applied Mechanics, VSB-Technical University of Ostrava, 17.listopadu 2172/15, Ostrava-Poruba, 708 33, Czech Republic. Electronic address: polzer@seznam.cz
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- $a Failure properties of abdominal aortic aneurysm tissue are orientation dependent / $c S. Polzer, V. Man, R. Vlachovský, L. Kubíček, J. Kracík, R. Staffa, T. Novotný, J. Burša, ML. Raghavan
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- $a INTRODUCTION: Biomechanical rupture risk assessment of abdominal aortic aneurysm (AAA) requires information about failure properties of aneurysmal tissue. There are large differences between reported values. Among others, studies vary in using either axially or circumferentially oriented samples. This study investigates the effect of sample orientation on failure properties. METHODS: Aneurysmal tissues from 45 patients (11 females) were harvested during open AAA repair, cut into uniaxial samples (90) and tested mechanically within 3 h. If possible, the samples were cut in both axial (49 samples) and circumferential (41 samples) directions. Wall thickness, First Piola-Kirchhoff strength Pult and ultimate tension Tult were recorded. Influence of sample orientation and other clinical parameters were investigated using non parametric tests. RESULTS: Medians of Pult (values 1100 kPa for circumferential vs. 715 kPa for axial direction, p < 10-4) and Tult (17.4 N/cm in circumferential vs. 11.2 N/cm in axial direction, p < 10-4) were significantly higher in circumferential direction. For paired data, the median of difference was 411 kPa (p < 10-3) in Pult and 7.4 N/cm (p < 10-4) in Tult in favor of circumferential direction. CONCLUSIONS: In this first study of anisotropy in AAA wall failure properties using paired comparisons, the strength in circumferential orientation was found to be higher than in axial orientation.
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- $a Man, Vojtěch $u Faculty of Mechanical Engineering, Brno University of Technology, Technická 2, Brno, 61669, Czech Republic
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- $a Vlachovský, Robert $u 2(nd) Department of Surgery, St. Anne's University Hospital Brno and Faculty of Medicine, Masaryk University, Brno, Czech Republic
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- $a Raghavan, M L $u Roy J. Carver Department of Biomedical Engineering, University of Iowa, 5605 Seamans Center, Iowa City, IA, 52242, USA
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