-
Something wrong with this record ?
Escherichia coli Sequence Type 457 Is an Emerging Extended-Spectrum-β-Lactam-Resistant Lineage with Reservoirs in Wildlife and Food-Producing Animals
K. Nesporova, ER. Wyrsch, A. Valcek, I. Bitar, K. Chaw, P. Harris, J. Hrabak, I. Literak, SP. Djordjevic, M. Dolejska
Language English Country United States
Document type Journal Article, Research Support, Non-U.S. Gov't
NLK
Free Medical Journals
from 1972 to 6 months ago
Freely Accessible Science Journals
from 1995 to 6 months ago
PubMed Central
from 1972 to 1 year ago
Europe PubMed Central
from 1972 to 6 months ago
Open Access Digital Library
from 1972-01-01
Open Access Digital Library
from 1972-01-01
PubMed
33020161
DOI
10.1128/aac.01118-20
Knihovny.cz E-resources
- MeSH
- Anti-Bacterial Agents pharmacology MeSH
- beta-Lactamases genetics MeSH
- beta-Lactams MeSH
- Animals, Wild MeSH
- Escherichia coli * genetics MeSH
- Phylogeny MeSH
- Escherichia coli Infections * veterinary MeSH
- Humans MeSH
- Plasmids genetics MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Geographicals
- Australia MeSH
Silver gulls carry phylogenetically diverse Escherichia coli, including globally dominant extraintestinal pathogenic E. coli (ExPEC) sequence types and pandemic ExPEC-ST131 clades; however, our large-scale study (504 samples) on silver gulls nesting off the coast of New South Wales identified E. coli ST457 as the most prevalent. A phylogenetic analysis of whole-genome sequences (WGS) of 138 ST457 samples comprising 42 from gulls, 2 from humans (Australia), and 14 from poultry farmed in Paraguay were compared with 80 WGS deposited in public databases from diverse sources and countries. E. coli ST457 strains are phylogenetic group F, carry fimH145, and partition into five main clades in accordance to predominant flagella H-antigen carriage. Although we identified considerable phylogenetic diversity among the 138 ST457 strains, closely related subclades (<100 SNPs) suggested zoonotic or zooanthroponosis transmission between humans, wild birds, and food-producing animals. Australian human clinical and gull strains in two of the clades were closely related (≤80 SNPs). Regarding plasmid content, country, or country/source, specific connections were observed, including I1/ST23, I1/ST314, and I1/ST315 disseminating blaCMY-2 in Australia, I1/ST113 carrying blaCTX-M-8 and mcr-5 in Paraguayan poultry, and F2:A-:B1 plasmids of Dutch origin being detected across multiple ST457 clades. We identified a high prevalence of nearly identical I1/ST23 plasmids carrying blaCMY-2 among Australian gull and clinical human strains. In summary, ST457 is a broad host range, geographically diverse E. coli lineage that can cause human extraintestinal disease, including urinary tract infection, and displays a remarkable ability to capture mobile elements that carry and transmit genes encoding resistance to critically important antibiotics.
CEITEC VFU Brno University of Veterinary and Pharmaceutical Sciences Brno Brno Czech Republic
Faculty of Medicine Biomedical Center Charles University Pilsen Czech Republic
Faculty of Medicine University of Queensland UQ Centre for Clinical Research Brisbane Australia
Pathology Queensland Brisbane Australia
The ithree institute University of Technology Sydney Sydney New South Wales Australia
References provided by Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc21019634
- 003
- CZ-PrNML
- 005
- 20210830101223.0
- 007
- ta
- 008
- 210728s2020 xxu f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.1128/AAC.01118-20 $2 doi
- 035 __
- $a (PubMed)33020161
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a xxu
- 100 1_
- $a Nesporova, Kristina $u CEITEC VFU Brno, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic $u Department of Biology and Wildlife Diseases, Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic
- 245 10
- $a Escherichia coli Sequence Type 457 Is an Emerging Extended-Spectrum-β-Lactam-Resistant Lineage with Reservoirs in Wildlife and Food-Producing Animals / $c K. Nesporova, ER. Wyrsch, A. Valcek, I. Bitar, K. Chaw, P. Harris, J. Hrabak, I. Literak, SP. Djordjevic, M. Dolejska
- 520 9_
- $a Silver gulls carry phylogenetically diverse Escherichia coli, including globally dominant extraintestinal pathogenic E. coli (ExPEC) sequence types and pandemic ExPEC-ST131 clades; however, our large-scale study (504 samples) on silver gulls nesting off the coast of New South Wales identified E. coli ST457 as the most prevalent. A phylogenetic analysis of whole-genome sequences (WGS) of 138 ST457 samples comprising 42 from gulls, 2 from humans (Australia), and 14 from poultry farmed in Paraguay were compared with 80 WGS deposited in public databases from diverse sources and countries. E. coli ST457 strains are phylogenetic group F, carry fimH145, and partition into five main clades in accordance to predominant flagella H-antigen carriage. Although we identified considerable phylogenetic diversity among the 138 ST457 strains, closely related subclades (<100 SNPs) suggested zoonotic or zooanthroponosis transmission between humans, wild birds, and food-producing animals. Australian human clinical and gull strains in two of the clades were closely related (≤80 SNPs). Regarding plasmid content, country, or country/source, specific connections were observed, including I1/ST23, I1/ST314, and I1/ST315 disseminating blaCMY-2 in Australia, I1/ST113 carrying blaCTX-M-8 and mcr-5 in Paraguayan poultry, and F2:A-:B1 plasmids of Dutch origin being detected across multiple ST457 clades. We identified a high prevalence of nearly identical I1/ST23 plasmids carrying blaCMY-2 among Australian gull and clinical human strains. In summary, ST457 is a broad host range, geographically diverse E. coli lineage that can cause human extraintestinal disease, including urinary tract infection, and displays a remarkable ability to capture mobile elements that carry and transmit genes encoding resistance to critically important antibiotics.
- 650 _2
- $a zvířata $7 D000818
- 650 _2
- $a divoká zvířata $7 D000835
- 650 _2
- $a antibakteriální látky $x farmakologie $7 D000900
- 650 12
- $a Escherichia coli $x genetika $7 D004926
- 650 12
- $a infekce vyvolané Escherichia coli $x veterinární $7 D004927
- 650 _2
- $a lidé $7 D006801
- 650 _2
- $a fylogeneze $7 D010802
- 650 _2
- $a plazmidy $x genetika $7 D010957
- 650 _2
- $a beta-laktamasy $x genetika $7 D001618
- 650 _2
- $a beta-laktamy $7 D047090
- 651 _2
- $a Austrálie $7 D001315
- 655 _2
- $a časopisecké články $7 D016428
- 655 _2
- $a práce podpořená grantem $7 D013485
- 700 1_
- $a Wyrsch, Ethan R $u The ithree institute, University of Technology Sydney, Sydney, New South Wales, Australia
- 700 1_
- $a Valcek, Adam $u CEITEC VFU Brno, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic $u Department of Biology and Wildlife Diseases, Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic $u Faculty of Medicine, Biomedical Center, Charles University, Pilsen, Czech Republic
- 700 1_
- $a Bitar, Ibrahim $u CEITEC VFU Brno, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic $u Faculty of Medicine, Biomedical Center, Charles University, Pilsen, Czech Republic
- 700 1_
- $a Chaw, Khin $u Faculty of Medicine, University of Queensland, UQ Centre for Clinical Research, Brisbane, Australia $u Pathology Queensland, Brisbane, Australia
- 700 1_
- $a Harris, Patrick $u Faculty of Medicine, University of Queensland, UQ Centre for Clinical Research, Brisbane, Australia $u Pathology Queensland, Brisbane, Australia
- 700 1_
- $a Hrabak, Jaroslav $u Faculty of Medicine, Biomedical Center, Charles University, Pilsen, Czech Republic
- 700 1_
- $a Literak, Ivan $u CEITEC VFU Brno, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic $u Department of Biology and Wildlife Diseases, Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic
- 700 1_
- $a Djordjevic, Steven P $u The ithree institute, University of Technology Sydney, Sydney, New South Wales, Australia
- 700 1_
- $a Dolejska, Monika $u CEITEC VFU Brno, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic monika.dolejska@gmail.com $u Department of Biology and Wildlife Diseases, Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic $u Faculty of Medicine, Biomedical Center, Charles University, Pilsen, Czech Republic
- 773 0_
- $w MED00009215 $t Antimicrobial agents and chemotherapy $x 1098-6596 $g Roč. 65, č. 1 (2020)
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/33020161 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y p $z 0
- 990 __
- $a 20210728 $b ABA008
- 991 __
- $a 20210830101223 $b ABA008
- 999 __
- $a ok $b bmc $g 1690450 $s 1140080
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2020 $b 65 $c 1 $e 20201216 $i 1098-6596 $m Antimicrobial agents and chemotherapy $n Antimicrob Agents Chemother $x MED00009215
- LZP __
- $a Pubmed-20210728
