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Should kidney allografts from old donors be allocated only to old recipients
C. Süsal, G. Kumru, B. Döhler, C. Morath, M. Baas, J. Lutz, C. Unterrainer, W. Arns, O. Aubert, C. Bara, A. Beiras-Fernandez, GA. Böhmig, C. Bösmüller, F. Diekmann, P. Dutkowski, I. Hauser, C. Legendre, VJ. Lozanovski, A. Mehrabi, A. Melk, T....
Language English Country Great Britain
Document type Journal Article
NLK
Medline Complete (EBSCOhost)
from 2004-05-01
Wiley Free Content
from 1997 to 2021
ROAD: Directory of Open Access Scholarly Resources
from 1988
PubMed
32337766
DOI
10.1111/tri.13628
Knihovny.cz E-resources
- MeSH
- Allografts MeSH
- Tissue Donors MeSH
- Kidney MeSH
- Middle Aged MeSH
- Humans MeSH
- Graft Survival MeSH
- Aged MeSH
- Kidney Transplantation * MeSH
- Age Factors MeSH
- Tissue and Organ Procurement * MeSH
- Check Tag
- Middle Aged MeSH
- Humans MeSH
- Aged MeSH
- Publication type
- Journal Article MeSH
- Geographicals
- Europe MeSH
In several deceased donor kidney allocation systems, organs from elderly donors are allocated primarily to elderly recipients. The Eurotransplant Senior Program (ESP) was implemented in 1999, and since then, especially in Europe, the use of organs from elderly donors has steadily increased. The proportion of ≥60-year-old donors reported to the Collaborative Transplant Study (CTS) by European centers has doubled, from 21% in 2000-2001 to 42% in 2016-2017. Therefore, in the era of organ shortage it is a matter of debate whether kidney organs from elderly donors should only be allocated to elderly recipients or whether <65-year-old recipients can also benefit from these generally as "marginal" categorized organs. To discuss this issue, a European Consensus Meeting was organized by the CTS on April 12, 2018, in Heidelberg, in which 36 experts participated. Based on available evidence, it was unanimously concluded that kidney organs from 65- to 74-year-old donors can also be allocated to 55- to 64-year-old recipients, especially if these organs are from donors with no history of hypertension, no increased creatinine, no cerebrovascular death, and no other reasons for defining a marginal donor, such as diabetes or cancer.
Department of General and Transplant Surgery University Hospital Heidelberg Heidelberg Germany
Department of Internal Medicine University of Giessen Giessen Germany
Department of Nephrology and Renal Transplantation ICNU Hospital Clinic Barcelona Spain
Department of Nephrology and Transplantation Cologne Merheim Medical Center Cologne Germany
Department of Nephrology Institute for Clinical and Experimental Medicine Prague Czech Republic
Department of Nephrology Klinikum rechts der Isar Technical University of Munich Munich Germany
Department of Nephrology Medinizische Klinik 3 UKF Goethe University Frankfurt Germany
Department of Pediatric Kidney Liver and Metabolic Diseases Hannover Medical School Hannover Germany
Department of Pediatrics 1 University Children's Hospital Heidelberg Heidelberg Germany
Division of Nephrology Heidelberg University Hospital Heidelberg Germany
Division of Nephrology University Hospital Zurich Zurich Switzerland
Institute of Immunology Heidelberg University Hospital Heidelberg Germany
Service de Néphrologie Dialyse Aphérèses et Transplantation CHU Grenoble Alpes Grenoble France
References provided by Crossref.org
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