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Prime Editing: A New Way for Genome Editing
M. Marzec, A. Brąszewska-Zalewska, G. Hensel
Trends in cell biology.
2020 ;
30 (4) :
257-259.
[pub] 20200127
Jazyk angličtina Země Velká Británie
Typ dokumentu časopisecké články
Perzistentní odkaz
https://www.medvik.cz/link/bmc21020675
- MeSH
- DNA genetika MeSH
- editace genu * MeSH
- guide RNA, Kinetoplastida genetika MeSH
- hybridizace genetická MeSH
- lidé MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
Precise and efficient use of genome editing tools are hampered by the introduction of DNA double-strand breaks, donor DNA templates, or homology-directed repair. A recent study expands the genome editing toolbox with the introduction of prime editing, which overcomes previous challenges and introduces insertions, deletions, and all putative 12 types of base-to-base conversions in human cells.
Citace poskytuje Crossref.org
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