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Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

N. Mullins, AJ. Forstner, KS. O'Connell, B. Coombes, JRI. Coleman, Z. Qiao, TD. Als, TB. Bigdeli, S. Børte, J. Bryois, AW. Charney, OK. Drange, MJ. Gandal, SP. Hagenaars, M. Ikeda, N. Kamitaki, M. Kim, K. Krebs, G. Panagiotaropoulou, BM....

. 2021 ; 53 (6) : 817-829. [pub] 20210517

Jazyk angličtina Země Spojené státy americké

Typ dokumentu časopisecké články, metaanalýza, Research Support, N.I.H., Extramural

Perzistentní odkaz   https://www.medvik.cz/link/bmc21025686

Grantová podpora
U01 MH085520 NIMH NIH HHS - United States
U01 MH094421 NIMH NIH HHS - United States
U01 MH109528 NIMH NIH HHS - United States
R01 MH119243 NIMH NIH HHS - United States
S10 OD018522 NIH HHS - United States
S10 OD026880 NIH HHS - United States

E-zdroje Online Plný text

NLK ProQuest Central od 2000-01-01 do Před 1 rokem
Health & Medicine (ProQuest) od 2000-01-01 do Před 1 rokem
Public Health Database (ProQuest) od 2000-01-01 do Před 1 rokem

Bipolar disorder is a heritable mental illness with complex etiology. We performed a genome-wide association study of 41,917 bipolar disorder cases and 371,549 controls of European ancestry, which identified 64 associated genomic loci. Bipolar disorder risk alleles were enriched in genes in synaptic signaling pathways and brain-expressed genes, particularly those with high specificity of expression in neurons of the prefrontal cortex and hippocampus. Significant signal enrichment was found in genes encoding targets of antipsychotics, calcium channel blockers, antiepileptics and anesthetics. Integrating expression quantitative trait locus data implicated 15 genes robustly linked to bipolar disorder via gene expression, encoding druggable targets such as HTR6, MCHR1, DCLK3 and FURIN. Analyses of bipolar disorder subtypes indicated high but imperfect genetic correlation between bipolar disorder type I and II and identified additional associated loci. Together, these results advance our understanding of the biological etiology of bipolar disorder, identify novel therapeutic leads and prioritize genes for functional follow-up studies.

1st Department of Psychiatry Eginition Hospital National and Kapodistrian University of Athens Athens Greece

2nd Department of Psychiatry Attikon General Hospital National and Kapodistrian University of Athens Athens Greece

Academic Psychiatry Newcastle University Newcastle upon Tyne UK

Analytic and Translational Genetics Unit Massachusetts General Hospital Boston MA USA

APHP Nord DMU Neurosciences Département de Psychiatrie et de Médecine Addictologique GHU Saint Louis Lariboisière Fernand Widal Paris France

Biochemistry and Molecular Biology Indiana University School of Medicine Indianapolis IN USA

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Cell Biology SUNY Downstate Medical Center College of Medicine Brooklyn NY USA

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Centre for Cognitive Ageing and Cognitive Epidemiology University of Edinburgh Edinburgh UK

Centre for Human Genetics University of Marburg Marburg Germany

Centre for Integrated Register Based Research Aarhus University Aarhus Denmark

Centre for Neuroimaging and Cognitive Genomics National University of Ireland Galway Galway Ireland

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Citace poskytuje Crossref.org

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$a Bigdeli, Tim B $u Department of Psychiatry and Behavioral Sciences, SUNY Downstate Health Sciences University, Brooklyn, NY, USA $u VA NY Harbor Healthcare System, Brooklyn, NY, USA
700    1_
$a Børte, Sigrid $u Research and Communication Unit for Musculoskeletal Health, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway $u Institute of Clinical Medicine, University of Oslo, Oslo, Norway $u K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway
700    1_
$a Bryois, Julien $u Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
700    1_
$a Charney, Alexander W $u Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA
700    1_
$a Drange, Ole Kristian $u Department of Mental Health, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim, Norway $u Department of Østmarka, Division of Mental Health Care, St Olavs Hospital, Trondheim University Hospital, Trondheim, Norway
700    1_
$a Gandal, Michael J $u Department of Psychiatry and Biobehavioral Science, Semel Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA
700    1_
$a Hagenaars, Saskia P $u Social, Genetic and Developmental Psychiatry Centre, King's College London, London, UK $u NIHR Maudsley BRC, King's College London, London, UK
700    1_
$a Ikeda, Masashi $u Department of Psychiatry, School of Medicine, Fujita Health University, Toyoake, Japan
700    1_
$a Kamitaki, Nolan $u Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, USA $u Department of Genetics, Harvard Medical School, Boston, MA, USA
700    1_
$a Kim, Minsoo $u Department of Psychiatry and Biobehavioral Science, Semel Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA
700    1_
$a Krebs, Kristi $u Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia
700    1_
$a Panagiotaropoulou, Georgia $u Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, Berlin, Germany
700    1_
$a Schilder, Brian M $u Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA $u Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA $u Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA $u Estelle and Daniel Maggin Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA
700    1_
$a Sloofman, Laura G $u Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA
700    1_
$a Steinberg, Stacy $u deCODE Genetics/Amgen, Reykjavik, Iceland
700    1_
$a Trubetskoy, Vassily $u Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, Berlin, Germany
700    1_
$a Winsvold, Bendik S $u K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway $u Department of Research, Innovation and Education, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway
700    1_
$a Won, Hong-Hee $u Samsung Advanced Institute for Health Sciences and Technology (SAIHST), Samsung Medical Center, Sungkyunkwan University, Seoul, South Korea
700    1_
$a Abramova, Liliya $u Russian Academy of Medical Sciences, Mental Health Research Center, Moscow, Russian Federation
700    1_
$a Adorjan, Kristina $u Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Munich, Germany $u Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany
700    1_
$a Agerbo, Esben $u iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark $u National Centre for Register-Based Research, Aarhus University, Aarhus, Denmark $u Centre for Integrated Register-Based Research, Aarhus University, Aarhus, Denmark
700    1_
$a Al Eissa, Mariam $u Division of Psychiatry, University College London, London, UK
700    1_
$a Albani, Diego $u Department of Neuroscience, Istituto Di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy
700    1_
$a Alliey-Rodriguez, Ney $u Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL, USA $u Northwestern University, Chicago, IL, USA
700    1_
$a Anjorin, Adebayo $u Psychiatry, Berkshire Healthcare NHS Foundation Trust, Bracknell, UK
700    1_
$a Antilla, Verneri $u Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA
700    1_
$a Antoniou, Anastasia $u 2nd Department of Psychiatry, Attikon General Hospital, National and Kapodistrian University of Athens, Athens, Greece
700    1_
$a Awasthi, Swapnil $u Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, Berlin, Germany
700    1_
$a Baek, Ji Hyun $u Department of Psychiatry, Samsung Medical Center, School of Medicine, Sungkyunkwan University, Seoul, South Korea
700    1_
$a Bækvad-Hansen, Marie $u iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark $u Center for Neonatal Screening, Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark
700    1_
$a Bass, Nicholas $u Division of Psychiatry, University College London, London, UK
700    1_
$a Bauer, Michael $u Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
700    1_
$a Beins, Eva C $u Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany
700    1_
$a Bergen, Sarah E $u Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
700    1_
$a Birner, Armin $u Department of Psychiatry and Psychotherapeutic Medicine, Medical University of Graz, Graz, Austria
700    1_
$a Bøcker Pedersen, Carsten $u iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark $u National Centre for Register-Based Research, Aarhus University, Aarhus, Denmark $u Centre for Integrated Register-Based Research, Aarhus University, Aarhus, Denmark
700    1_
$a Bøen, Erlend $u Department of Psychiatric Research, Diakonhjemmet Hospital, Oslo, Norway
700    1_
$a Boks, Marco P $u Psychiatry, Brain Center UMC Utrecht, Utrecht, the Netherlands
700    1_
$a Bosch, Rosa $u Instituto de Salud Carlos III, Biomedical Network Research Centre on Mental Health (CIBERSAM), Madrid, Spain $u Department of Psychiatry, Hospital Universitari Vall d´Hebron, Barcelona, Spain $u Department of Psychiatry and Forensic Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain $u Psychiatric Genetics Unit, Group of Psychiatry Mental Health and Addictions, Vall d´Hebron Research Institut (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain
700    1_
$a Brum, Murielle $u Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt am Main, Germany
700    1_
$a Brumpton, Ben M $u K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway
700    1_
$a Brunkhorst-Kanaan, Nathalie $u Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt am Main, Germany
700    1_
$a Budde, Monika $u Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Munich, Germany
700    1_
$a Bybjerg-Grauholm, Jonas $u iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark $u Center for Neonatal Screening, Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark
700    1_
$a Byerley, William $u Psychiatry, University of California San Francisco, San Francisco, CA, USA
700    1_
$a Cairns, Murray $u University of Newcastle, Newcastle, New South Wales, Australia
700    1_
$a Casas, Miquel $u Instituto de Salud Carlos III, Biomedical Network Research Centre on Mental Health (CIBERSAM), Madrid, Spain $u Department of Psychiatry, Hospital Universitari Vall d´Hebron, Barcelona, Spain $u Department of Psychiatry and Forensic Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain $u Psychiatric Genetics Unit, Group of Psychiatry Mental Health and Addictions, Vall d´Hebron Research Institut (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain
700    1_
$a Cervantes, Pablo $u Mood Disorders Program, Department of Psychiatry, McGill University Health Center, Montreal, Quebec, Canada
700    1_
$a Clarke, Toni-Kim $u Division of Psychiatry, University of Edinburgh, Edinburgh, UK
700    1_
$a Cruceanu, Cristiana $u Mood Disorders Program, Department of Psychiatry, McGill University Health Center, Montreal, Quebec, Canada $u Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany
700    1_
$a Cuellar-Barboza, Alfredo $u Department of Psychiatry, Universidad Autonoma de Nuevo Leon, Monterrey, Mexico $u Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA
700    1_
$a Cunningham, Julie $u Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA
700    1_
$a Curtis, David $u Centre for Psychiatry, Queen Mary University of London, London, UK $u UCL Genetics Institute, University College London, London, UK
700    1_
$a Czerski, Piotr M $u Department of Psychiatry, Laboratory of Psychiatric Genetics, Poznan University of Medical Sciences, Poznan, Poland
700    1_
$a Dale, Anders M $u Center for Multimodal Imaging and Genetics, Departments of Neurosciences, Radiology, and Psychiatry, University of California, San Diego, CA, USA
700    1_
$a Dalkner, Nina $u Department of Psychiatry and Psychotherapeutic Medicine, Medical University of Graz, Graz, Austria
700    1_
$a David, Friederike S $u Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany
700    1_
$a Degenhardt, Franziska $u Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany $u Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Essen, University of Duisburg-Essen, Duisburg, Germany
700    1_
$a Djurovic, Srdjan $u Department of Medical Genetics, Oslo University Hospital, Oslo, Norway $u NORMENT, Department of Clinical Science, University of Bergen, Bergen, Norway
700    1_
$a Dobbyn, Amanda L $u Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA $u Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA
700    1_
$a Douzenis, Athanassios $u 2nd Department of Psychiatry, Attikon General Hospital, National and Kapodistrian University of Athens, Athens, Greece
700    1_
$a Elvsåshagen, Torbjørn $u Institute of Clinical Medicine, University of Oslo, Oslo, Norway $u Department of Neurology, Oslo University Hospital, Oslo, Norway $u NORMENT, KG Jebsen Centre for Psychosis Research, Oslo University Hospital, Oslo, Norway
700    1_
$a Escott-Price, Valentina $u Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK
700    1_
$a Ferrier, I Nicol $u Academic Psychiatry, Newcastle University, Newcastle upon Tyne, UK
700    1_
$a Fiorentino, Alessia $u Division of Psychiatry, University College London, London, UK
700    1_
$a Foroud, Tatiana M $u Department of Medical and Molecular Genetics, Indiana University, Indianapolis, IN, USA
700    1_
$a Forty, Liz $u Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK
700    1_
$a Frank, Josef $u Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany
700    1_
$a Frei, Oleksandr $u Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway $u Institute of Clinical Medicine, University of Oslo, Oslo, Norway
700    1_
$a Freimer, Nelson B $u Department of Psychiatry and Biobehavioral Science, Semel Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA $u Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA, USA
700    1_
$a Frisén, Louise $u Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
700    1_
$a Gade, Katrin $u Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Munich, Germany $u Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany
700    1_
$a Garnham, Julie $u Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada
700    1_
$a Gelernter, Joel $u Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA $u Veterans Affairs Connecticut Healthcare System, West Haven, CT, USA $u Departments of Genetics and Neuroscience, Yale University School of Medicine, New Haven, CT, USA
700    1_
$a Giørtz Pedersen, Marianne $u iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark $u National Centre for Register-Based Research, Aarhus University, Aarhus, Denmark $u Centre for Integrated Register-Based Research, Aarhus University, Aarhus, Denmark
700    1_
$a Gizer, Ian R $u Department of Psychological Sciences, University of Missouri, Columbia, MO, USA
700    1_
$a Gordon, Scott D $u Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia
700    1_
$a Gordon-Smith, Katherine $u Psychological Medicine, University of Worcester, Worcester, UK
700    1_
$a Greenwood, Tiffany A $u Department of Psychiatry, University of California San Diego, La Jolla, CA, USA
700    1_
$a Grove, Jakob $u iSEQ, Center for Integrative Sequencing, Aarhus University, Aarhus, Denmark $u Department of Biomedicine - Human Genetics, Aarhus University, Aarhus, Denmark $u iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark $u Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark
700    1_
$a Guzman-Parra, José $u Mental Health Department, University Regional Hospital, Biomedicine Institute (IBIMA), Málaga, Spain
700    1_
$a Ha, Kyooseob $u Department of Psychiatry, Seoul National University College of Medicine, Seoul, South Korea
700    1_
$a Haraldsson, Magnus $u Landspitali University Hospital, Reykjavik, Iceland
700    1_
$a Hautzinger, Martin $u Department of Psychology, Eberhard Karls Universität Tübingen, Tübingen, Germany
700    1_
$a Heilbronner, Urs $u Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Munich, Germany
700    1_
$a Hellgren, Dennis $u Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
700    1_
$a Herms, Stefan $u Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany $u Department of Biomedicine, University of Basel, Basel, Switzerland $u Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland
700    1_
$a Hoffmann, Per $u Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany $u Department of Biomedicine, University of Basel, Basel, Switzerland $u Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland
700    1_
$a Holmans, Peter A $u Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK
700    1_
$a Huckins, Laura $u Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA $u Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA
700    1_
$a Jamain, Stéphane $u Neuropsychiatrie Translationnelle, Inserm U955, Créteil, France $u Faculté de Santé, Université Paris Est, Créteil, France
700    1_
$a Johnson, Jessica S $u Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA $u Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA
700    1_
$a Kalman, Janos L $u Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Munich, Germany $u Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany $u International Max Planck Research School for Translational Psychiatry (IMPRS-TP), Munich, Germany
700    1_
$a Kamatani, Yoichiro $u Laboratory of Complex Trait Genomics, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan $u Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan
700    1_
$a Kennedy, James L $u Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada $u Neurogenetics Section, Centre for Addiction and Mental Health, Toronto, Ontario, Canada $u Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada $u Institute of Medical Sciences, University of Toronto, Toronto, Ontario, Canada
700    1_
$a Kittel-Schneider, Sarah $u Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt am Main, Germany $u Department of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University Hospital Würzburg, Würzburg, Germany
700    1_
$a Knowles, James A $u Cell Biology, SUNY Downstate Medical Center College of Medicine, Brooklyn, NY, USA $u Institute for Genomic Health, SUNY Downstate Medical Center College of Medicine, Brooklyn, NY, USA
700    1_
$a Kogevinas, Manolis $u ISGlobal, Barcelona, Spain
700    1_
$a Koromina, Maria $u Laboratory of Pharmacogenomics and Individualized Therapy, Department of Pharmacy, School of Health Sciences, University of Patras, Patras, Greece
700    1_
$a Kranz, Thorsten M $u Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt am Main, Germany
700    1_
$a Kranzler, Henry R $u Mental Illness Research, Education and Clinical Center, Crescenz VAMC, Philadelphia, PA, USA $u Center for Studies of Addiction, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA
700    1_
$a Kubo, Michiaki $u RIKEN Center for Integrative Medical Sciences, Yokohama, Japan
700    1_
$a Kupka, Ralph $u Psychiatry, Altrecht, Utrecht, the Netherlands $u Psychiatry, GGZ inGeest, Amsterdam, the Netherlands $u Psychiatry, VU Medisch Centrum, Amsterdam, the Netherlands
700    1_
$a Kushner, Steven A $u Department of Psychiatry, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands
700    1_
$a Lavebratt, Catharina $u Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden $u Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden
700    1_
$a Lawrence, Jacob $u Psychiatry, North East London NHS Foundation Trust, Ilford, UK
700    1_
$a Leber, Markus $u Clinic for Psychiatry and Psychotherapy, University Hospital Cologne, Cologne, Germany
700    1_
$a Lee, Heon-Jeong $u Department of Psychiatry, Korea University College of Medicine, Seoul, South Korea
700    1_
$a Lee, Phil H $u Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
700    1_
$a Levy, Shawn E $u HudsonAlpha Institute for Biotechnology, Huntsville, AL, USA
700    1_
$a Lewis, Catrin $u Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK
700    1_
$a Liao, Calwing $u Department of Human Genetics, McGill University, Montréal, Quebec, Canada $u Montreal Neurological Institute and Hospital, McGill University, Montréal, Quebec, Canada
700    1_
$a Lucae, Susanne $u Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany
700    1_
$a Lundberg, Martin $u Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden $u Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden
700    1_
$a MacIntyre, Donald J $u Division of Psychiatry, Centre for Clinical Brain Sciences, The University of Edinburgh, Edinburgh, UK
700    1_
$a Magnusson, Sigurdur H $u deCODE Genetics/Amgen, Reykjavik, Iceland
700    1_
$a Maier, Wolfgang $u Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany
700    1_
$a Maihofer, Adam $u Department of Psychiatry, University of California San Diego, La Jolla, CA, USA
700    1_
$a Malaspina, Dolores $u Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA $u Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA
700    1_
$a Maratou, Eirini $u Clinical Biochemistry Laboratory, Attikon General Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece
700    1_
$a Martinsson, Lina $u Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
700    1_
$a Mattheisen, Manuel $u iSEQ, Center for Integrative Sequencing, Aarhus University, Aarhus, Denmark $u Department of Biomedicine - Human Genetics, Aarhus University, Aarhus, Denmark $u iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark $u Department of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University Hospital Würzburg, Würzburg, Germany $u Department of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden
700    1_
$a McCarroll, Steven A $u Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, USA $u Department of Genetics, Harvard Medical School, Boston, MA, USA
700    1_
$a McGregor, Nathaniel W $u Systems Genetics Working Group, Department of Genetics, Stellenbosch University, Stellenbosch, South Africa
700    1_
$a McGuffin, Peter $u Social, Genetic and Developmental Psychiatry Centre, King's College London, London, UK
700    1_
$a McKay, James D $u Genetic Cancer Susceptibility Group, International Agency for Research on Cancer, Lyon, France
700    1_
$a Medeiros, Helena $u Institute for Genomic Health, SUNY Downstate Medical Center College of Medicine, Brooklyn, NY, USA
700    1_
$a Medland, Sarah E $u Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia
700    1_
$a Millischer, Vincent $u Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden $u Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden
700    1_
$a Montgomery, Grant W $u Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia
700    1_
$a Moran, Jennifer L $u Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, USA $u Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA
700    1_
$a Morris, Derek W $u Centre for Neuroimaging and Cognitive Genomics (NICOG), National University of Ireland Galway, Galway, Ireland
700    1_
$a Mühleisen, Thomas W $u Institute of Neuroscience and Medicine (INM-1), Research Centre Jülich, Jülich, Germany $u Department of Biomedicine, University of Basel, Basel, Switzerland
700    1_
$a O'Brien, Niamh $u Division of Psychiatry, University College London, London, UK
700    1_
$a O'Donovan, Claire $u Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada
700    1_
$a Olde Loohuis, Loes M $u Department of Psychiatry and Biobehavioral Science, Semel Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA $u Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA, USA
700    1_
$a Oruc, Lilijana $u Medical Faculty, School of Science and Technology, University Sarajevo, Sarajevo, Bosnia and Herzegovina
700    1_
$a Papiol, Sergi $u Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Munich, Germany $u Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany
700    1_
$a Pardiñas, Antonio F $u Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK
700    1_
$a Perry, Amy $u Psychological Medicine, University of Worcester, Worcester, UK
700    1_
$a Pfennig, Andrea $u Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
700    1_
$a Porichi, Evgenia $u 2nd Department of Psychiatry, Attikon General Hospital, National and Kapodistrian University of Athens, Athens, Greece
700    1_
$a Potash, James B $u Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA
700    1_
$a Quested, Digby $u Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford, UK $u Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK
700    1_
$a Raj, Towfique $u Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA $u Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA $u Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA $u Estelle and Daniel Maggin Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA
700    1_
$a Rapaport, Mark H $u Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA
700    1_
$a DePaulo, J Raymond $u Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA
700    1_
$a Regeer, Eline J $u Outpatient Clinic for Bipolar Disorder, Altrecht, Utrecht, the Netherlands
700    1_
$a Rice, John P $u Department of Psychiatry, Washington University in Saint Louis, Saint Louis, MO, USA
700    1_
$a Rivas, Fabio $u Mental Health Department, University Regional Hospital, Biomedicine Institute (IBIMA), Málaga, Spain
700    1_
$a Rivera, Margarita $u Department of Biochemistry and Molecular Biology II, Faculty of Pharmacy, University of Granada, Granada, Spain $u Institute of Neurosciences, Biomedical Research Center (CIBM), University of Granada, Granada, Spain
700    1_
$a Roth, Julian $u Department of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University Hospital Würzburg, Würzburg, Germany
700    1_
$a Roussos, Panos $u Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA $u Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA $u Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA
700    1_
$a Ruderfer, Douglas M $u Medicine, Psychiatry, Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA
700    1_
$a Sánchez-Mora, Cristina $u Instituto de Salud Carlos III, Biomedical Network Research Centre on Mental Health (CIBERSAM), Madrid, Spain $u Department of Psychiatry, Hospital Universitari Vall d´Hebron, Barcelona, Spain $u Psychiatric Genetics Unit, Group of Psychiatry Mental Health and Addictions, Vall d´Hebron Research Institut (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain $u Department of Genetics, Microbiology and Statistics, Faculty of Biology, Universitat de Barcelona, Barcelona, Spain
700    1_
$a Schulte, Eva C $u Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Munich, Germany $u Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany
700    1_
$a Senner, Fanny $u Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Munich, Germany $u Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany
700    1_
$a Sharp, Sally $u Division of Psychiatry, University College London, London, UK
700    1_
$a Shilling, Paul D $u Department of Psychiatry, University of California San Diego, La Jolla, CA, USA
700    1_
$a Sigurdsson, Engilbert $u Landspitali University Hospital, Reykjavik, Iceland $u Faculty of Medicine, Department of Psychiatry, School of Health Sciences, University of Iceland, Reykjavik, Iceland
700    1_
$a Sirignano, Lea $u Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany
700    1_
$a Slaney, Claire $u Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada
700    1_
$a Smeland, Olav B $u Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway $u NORMENT, University of Oslo, Oslo, Norway
700    1_
$a Smith, Daniel J $u Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK
700    1_
$a Sobell, Janet L $u Psychiatry and the Behavioral Sciences, University of Southern California, Los Angeles, CA, USA
700    1_
$a Søholm Hansen, Christine $u iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark $u Center for Neonatal Screening, Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark
700    1_
$a Soler Artigas, Maria $u Instituto de Salud Carlos III, Biomedical Network Research Centre on Mental Health (CIBERSAM), Madrid, Spain $u Department of Psychiatry, Hospital Universitari Vall d´Hebron, Barcelona, Spain $u Psychiatric Genetics Unit, Group of Psychiatry Mental Health and Addictions, Vall d´Hebron Research Institut (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain $u Department of Genetics, Microbiology and Statistics, Faculty of Biology, Universitat de Barcelona, Barcelona, Spain
700    1_
$a Spijker, Anne T $u Mood Disorders, PsyQ, Rotterdam, the Netherlands
700    1_
$a Stein, Dan J $u SAMRC Unit on Risk and Resilience in Mental Disorders, Department of Psychiatry and Neuroscience Institute, University of Cape Town, Cape Town, South Africa
700    1_
$a Strauss, John S $u Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
700    1_
$a Świątkowska, Beata $u Department of Environmental Epidemiology, Nofer Institute of Occupational Medicine, Lodz, Poland
700    1_
$a Terao, Chikashi $u Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan
700    1_
$a Thorgeirsson, Thorgeir E $u deCODE Genetics/Amgen, Reykjavik, Iceland
700    1_
$a Toma, Claudio $u Neuroscience Research Australia, Sydney, New South Wales, Australia $u School of Medical Sciences, University of New South Wales, Sydney, New South Wales, Australia $u Centro de Biología Molecular Severo Ochoa, Universidad Autónoma de Madrid and CSIC, Madrid, Spain
700    1_
$a Tooney, Paul $u University of Newcastle, Newcastle, New South Wales, Australia
700    1_
$a Tsermpini, Evangelia-Eirini $u Laboratory of Pharmacogenomics and Individualized Therapy, Department of Pharmacy, School of Health Sciences, University of Patras, Patras, Greece
700    1_
$a Vawter, Marquis P $u Department of Psychiatry and Human Behavior, School of Medicine, University of California, Irvine, Irvine, CA, USA
700    1_
$a Vedder, Helmut $u Psychiatry, Psychiatrisches Zentrum Nordbaden, Wiesloch, Germany
700    1_
$a Walters, James T R $u Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK
700    1_
$a Witt, Stephanie H $u Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany
700    1_
$a Xi, Simon $u Computational Sciences Center of Emphasis, Pfizer Global Research and Development, Cambridge, MA, USA
700    1_
$a Xu, Wei $u Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada
700    1_
$a Yang, Jessica Mei Kay $u Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK
700    1_
$a Young, Allan H $u Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK $u South London and Maudsley NHS Foundation Trust, Bethlem Royal Hospital, Beckenham, UK
700    1_
$a Young, Hannah $u Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA
700    1_
$a Zandi, Peter P $u Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA
700    1_
$a Zhou, Hang $u Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA $u Veterans Affairs Connecticut Healthcare System, West Haven, CT, USA
700    1_
$a Zillich, Lea $u Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany
700    1_
$a Adolfsson, Rolf $u Department of Clinical Sciences, Psychiatry, Umeå University Medical Faculty, Umeå, Sweden
700    1_
$a Agartz, Ingrid $u Department of Psychiatric Research, Diakonhjemmet Hospital, Oslo, Norway $u Department of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden $u NORMENT, KG Jebsen Centre for Psychosis Research, Division of Mental Health and Addiction, Institute of Clinical Medicine and Diakonhjemmet Hospital, University of Oslo, Oslo, Norway
700    1_
$a Alda, Martin $u Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada $u National Institute of Mental Health, Klecany, Czech Republic
700    1_
$a Alfredsson, Lars $u Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
700    1_
$a Babadjanova, Gulja $u Institute of Pulmonology, Russian State Medical University, Moscow, Russian Federation
700    1_
$a Backlund, Lena $u Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden $u Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden
700    1_
$a Baune, Bernhard T $u Department of Psychiatry, University of Münster, Münster, Germany $u Department of Psychiatry, Melbourne Medical School, The University of Melbourne, Melbourne, Victoria, Australia $u The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria, Australia
700    1_
$a Bellivier, Frank $u Université de Paris, INSERM, Optimisation Thérapeutique en Neuropsychopharmacologie, UMRS 1144, Paris, France $u APHP Nord, DMU Neurosciences, Département de Psychiatrie et de Médecine Addictologique, GHU Saint Louis-Lariboisière-Fernand Widal, Paris, France
700    1_
$a Bengesser, Susanne $u Department of Psychiatry and Psychotherapeutic Medicine, Medical University of Graz, Graz, Austria
700    1_
$a Berrettini, Wade H $u Psychiatry, University of Pennsylvania, Philadelphia, PA, USA
700    1_
$a Blackwood, Douglas H R $u Division of Psychiatry, University of Edinburgh, Edinburgh, UK
700    1_
$a Boehnke, Michael $u Center for Statistical Genetics and Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA
700    1_
$a Børglum, Anders D $u iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark $u Department of Biomedicine and the iSEQ Center, Aarhus University, Aarhus, Denmark $u Center for Genomics and Personalized Medicine, CGPM, Aarhus, Denmark
700    1_
$a Breen, Gerome $u Social, Genetic and Developmental Psychiatry Centre, King's College London, London, UK $u NIHR Maudsley BRC, King's College London, London, UK
700    1_
$a Carr, Vaughan J $u School of Psychiatry, University of New South Wales, Sydney, New South Wales, Australia
700    1_
$a Catts, Stanley $u University of Queensland, Brisbane, Queensland, Australia
700    1_
$a Corvin, Aiden $u Neuropsychiatric Genetics Research Group, Department of Psychiatry and Trinity Translational Medicine Institute, Trinity College Dublin, Dublin, Ireland
700    1_
$a Craddock, Nicholas $u Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK
700    1_
$a Dannlowski, Udo $u Department of Psychiatry, University of Münster, Münster, Germany
700    1_
$a Dikeos, Dimitris $u 1st Department of Psychiatry, Eginition Hospital, National and Kapodistrian University of Athens, Athens, Greece
700    1_
$a Esko, Tõnu $u Department of Genetics, Harvard Medical School, Boston, MA, USA $u Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia $u Medical and Population Genetics, Broad Institute, Cambridge, MA, USA $u Division of Endocrinology, Children's Hospital Boston, Boston, MA, USA
700    1_
$a Etain, Bruno $u Université de Paris, INSERM, Optimisation Thérapeutique en Neuropsychopharmacologie, UMRS 1144, Paris, France $u APHP Nord, DMU Neurosciences, Département de Psychiatrie et de Médecine Addictologique, GHU Saint Louis-Lariboisière-Fernand Widal, Paris, France
700    1_
$a Ferentinos, Panagiotis $u Social, Genetic and Developmental Psychiatry Centre, King's College London, London, UK $u 2nd Department of Psychiatry, Attikon General Hospital, National and Kapodistrian University of Athens, Athens, Greece
700    1_
$a Frye, Mark $u Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA
700    1_
$a Fullerton, Janice M $u Neuroscience Research Australia, Sydney, New South Wales, Australia $u School of Medical Sciences, University of New South Wales, Sydney, New South Wales, Australia
700    1_
$a Gawlik, Micha $u Department of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University Hospital Würzburg, Würzburg, Germany
700    1_
$a Gershon, Elliot S $u Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL, USA $u Department of Human Genetics, University of Chicago, Chicago, IL, USA
700    1_
$a Goes, Fernando S $u Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA
700    1_
$a Green, Melissa J $u Neuroscience Research Australia, Sydney, New South Wales, Australia $u School of Psychiatry, University of New South Wales, Sydney, New South Wales, Australia
700    1_
$a Grigoroiu-Serbanescu, Maria $u Biometric Psychiatric Genetics Research Unit, Alexandru Obregia Clinical Psychiatric Hospital, Bucharest, Romania
700    1_
$a Hauser, Joanna $u Department of Psychiatry, Laboratory of Psychiatric Genetics, Poznan University of Medical Sciences, Poznan, Poland
700    1_
$a Henskens, Frans $u University of Newcastle, Newcastle, New South Wales, Australia
700    1_
$a Hillert, Jan $u Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
700    1_
$a Hong, Kyung Sue $u Department of Psychiatry, Samsung Medical Center, School of Medicine, Sungkyunkwan University, Seoul, South Korea
700    1_
$a Hougaard, David M $u iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark $u Center for Neonatal Screening, Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark
700    1_
$a Hultman, Christina M $u Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
700    1_
$a Hveem, Kristian $u K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway $u HUNT Research Center, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway
700    1_
$a Iwata, Nakao $u Department of Psychiatry, School of Medicine, Fujita Health University, Toyoake, Japan
700    1_
$a Jablensky, Assen V $u University of Western Australia, Nedlands, Western Australia, Australia
700    1_
$a Jones, Ian $u Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK
700    1_
$a Jones, Lisa A $u Psychological Medicine, University of Worcester, Worcester, UK
700    1_
$a Kahn, René S $u Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA $u Psychiatry, Brain Center UMC Utrecht, Utrecht, the Netherlands
700    1_
$a Kelsoe, John R $u Department of Psychiatry, University of California San Diego, La Jolla, CA, USA
700    1_
$a Kirov, George $u Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK
700    1_
$a Landén, Mikael $u Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden $u Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden
700    1_
$a Leboyer, Marion $u Neuropsychiatrie Translationnelle, Inserm U955, Créteil, France $u Faculté de Santé, Université Paris Est, Créteil, France $u Department of Psychiatry and Addiction Medicine, Assistance Publique - Hôpitaux de Paris, Paris, France
700    1_
$a Lewis, Cathryn M $u Social, Genetic and Developmental Psychiatry Centre, King's College London, London, UK $u NIHR Maudsley BRC, King's College London, London, UK $u Department of Medical and Molecular Genetics, King's College London, London, UK
700    1_
$a Li, Qingqin S $u Neuroscience Therapeutic Area, Janssen Research and Development, LLC, Titusville, NJ, USA
700    1_
$a Lissowska, Jolanta $u Cancer Epidemiology and Prevention, M. Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland
700    1_
$a Lochner, Christine $u SA MRC Unit on Risk and Resilience in Mental Disorders, Department of Psychiatry, Stellenbosch University, Stellenbosch, South Africa
700    1_
$a Loughland, Carmel $u University of Newcastle, Newcastle, New South Wales, Australia
700    1_
$a Martin, Nicholas G $u Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia $u School of Psychology, The University of Queensland, Brisbane, Queensland, Australia
700    1_
$a Mathews, Carol A $u Department of Psychiatry and Genetics Institute, University of Florida, Gainesville, FL, USA
700    1_
$a Mayoral, Fermin $u Mental Health Department, University Regional Hospital, Biomedicine Institute (IBIMA), Málaga, Spain
700    1_
$a McElroy, Susan L $u Research Institute, Lindner Center of HOPE, Mason, OH, USA
700    1_
$a McIntosh, Andrew M $u Division of Psychiatry, Centre for Clinical Brain Sciences, The University of Edinburgh, Edinburgh, UK $u Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK
700    1_
$a McMahon, Francis J $u Human Genetics Branch, Intramural Research Program, National Institute of Mental Health, Bethesda, MD, USA
700    1_
$a Melle, Ingrid $u Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway $u Division of Mental Health and Addiction, University of Oslo, Institute of Clinical Medicine, Oslo, Norway
700    1_
$a Michie, Patricia $u University of Newcastle, Newcastle, New South Wales, Australia
700    1_
$a Milani, Lili $u Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia
700    1_
$a Mitchell, Philip B $u School of Psychiatry, University of New South Wales, Sydney, New South Wales, Australia
700    1_
$a Morken, Gunnar $u Department of Mental Health, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim, Norway $u Psychiatry, St Olavs University Hospital, Trondheim, Norway
700    1_
$a Mors, Ole $u iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark $u Psychosis Research Unit, Aarhus University Hospital - Psychiatry, Risskov, Denmark
700    1_
$a Mortensen, Preben Bo $u iSEQ, Center for Integrative Sequencing, Aarhus University, Aarhus, Denmark $u iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark $u National Centre for Register-Based Research, Aarhus University, Aarhus, Denmark $u Centre for Integrated Register-Based Research, Aarhus University, Aarhus, Denmark
700    1_
$a Mowry, Bryan $u University of Queensland, Brisbane, Queensland, Australia
700    1_
$a Müller-Myhsok, Bertram $u Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany $u Munich Cluster for Systems Neurology (SyNergy), Munich, Germany $u University of Liverpool, Liverpool, UK
700    1_
$a Myers, Richard M $u HudsonAlpha Institute for Biotechnology, Huntsville, AL, USA
700    1_
$a Neale, Benjamin M $u Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, USA $u Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA $u Medical and Population Genetics, Broad Institute, Cambridge, MA, USA
700    1_
$a Nievergelt, Caroline M $u Department of Psychiatry, University of California San Diego, La Jolla, CA, USA $u Research/Psychiatry, Veterans Affairs San Diego Healthcare System, San Diego, CA, USA
700    1_
$a Nordentoft, Merete $u iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark $u Mental Health Services in the Capital Region of Denmark, Mental Health Center Copenhagen, University of Copenhagen, Copenhagen, Denmark
700    1_
$a Nöthen, Markus M $u Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany
700    1_
$a O'Donovan, Michael C $u Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK
700    1_
$a Oedegaard, Ketil J $u Division of Psychiatry, Haukeland Universitetssjukehus, Bergen, Norway $u Faculty of Medicine and Dentistry, University of Bergen, Bergen, Norway
700    1_
$a Olsson, Tomas $u Department of Clinical Neuroscience and Center for Molecular Medicine, Karolinska Institutet at Karolinska University Hospital, Solna, Sweden
700    1_
$a Owen, Michael J $u Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK
700    1_
$a Paciga, Sara A $u Human Genetics and Computational Biomedicine, Pfizer Global Research and Development, Groton, CT, USA
700    1_
$a Pantelis, Chris $u University of Melbourne, Melbourne, Victoria, Australia
700    1_
$a Pato, Carlos $u Institute for Genomic Health, SUNY Downstate Medical Center College of Medicine, Brooklyn, NY, USA
700    1_
$a Pato, Michele T $u Institute for Genomic Health, SUNY Downstate Medical Center College of Medicine, Brooklyn, NY, USA
700    1_
$a Patrinos, George P $u Laboratory of Pharmacogenomics and Individualized Therapy, Department of Pharmacy, School of Health Sciences, University of Patras, Patras, Greece $u Department of Pathology, College of Medicine and Health Sciences, United Arab Emirates University, Al-Ain, United Arab Emirates $u Zayed Center of Health Sciences, United Arab Emirates University, Al-Ain, United Arab Emirates
700    1_
$a Perlis, Roy H $u Psychiatry, Harvard Medical School, Boston, MA, USA $u Division of Clinical Research, Massachusetts General Hospital, Boston, MA, USA
700    1_
$a Posthuma, Danielle $u Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands $u Department of Clinical Genetics, Amsterdam Neuroscience, Vrije Universiteit Medical Center, Amsterdam, the Netherlands
700    1_
$a Ramos-Quiroga, Josep Antoni $u Instituto de Salud Carlos III, Biomedical Network Research Centre on Mental Health (CIBERSAM), Madrid, Spain $u Department of Psychiatry, Hospital Universitari Vall d´Hebron, Barcelona, Spain $u Department of Psychiatry and Forensic Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain $u Psychiatric Genetics Unit, Group of Psychiatry Mental Health and Addictions, Vall d´Hebron Research Institut (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain
700    1_
$a Reif, Andreas $u Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt am Main, Germany
700    1_
$a Reininghaus, Eva Z $u Department of Psychiatry and Psychotherapeutic Medicine, Medical University of Graz, Graz, Austria
700    1_
$a Ribasés, Marta $u Instituto de Salud Carlos III, Biomedical Network Research Centre on Mental Health (CIBERSAM), Madrid, Spain $u Department of Psychiatry, Hospital Universitari Vall d´Hebron, Barcelona, Spain $u Psychiatric Genetics Unit, Group of Psychiatry Mental Health and Addictions, Vall d´Hebron Research Institut (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain $u Department of Genetics, Microbiology and Statistics, Faculty of Biology, Universitat de Barcelona, Barcelona, Spain
700    1_
$a Rietschel, Marcella $u Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany
700    1_
$a Ripke, Stephan $u Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, USA $u Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, Berlin, Germany $u Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA
700    1_
$a Rouleau, Guy A $u Montreal Neurological Institute and Hospital, McGill University, Montréal, Quebec, Canada $u Department of Neurology and Neurosurgery, Faculty of Medicine, McGill University, Montreal, Quebec, Canada
700    1_
$a Saito, Takeo $u Department of Psychiatry, School of Medicine, Fujita Health University, Toyoake, Japan
700    1_
$a Schall, Ulrich $u University of Newcastle, Newcastle, New South Wales, Australia
700    1_
$a Schalling, Martin $u Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden $u Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden
700    1_
$a Schofield, Peter R $u Neuroscience Research Australia, Sydney, New South Wales, Australia $u School of Medical Sciences, University of New South Wales, Sydney, New South Wales, Australia
700    1_
$a Schulze, Thomas G $u Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Munich, Germany $u Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany $u Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany $u Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA $u Department of Psychiatry and Behavioral Sciences, SUNY Upstate Medical University, Syracuse, NY, USA
700    1_
$a Scott, Laura J $u Center for Statistical Genetics and Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA
700    1_
$a Scott, Rodney J $u University of Newcastle, Newcastle, New South Wales, Australia
700    1_
$a Serretti, Alessandro $u Department of Biomedical and NeuroMotor Sciences, University of Bologna, Bologna, Italy
700    1_
$a Shannon Weickert, Cynthia $u Neuroscience Research Australia, Sydney, New South Wales, Australia $u School of Psychiatry, University of New South Wales, Sydney, New South Wales, Australia $u Department of Neuroscience, SUNY Upstate Medical University, Syracuse, NY, USA
700    1_
$a Smoller, Jordan W $u Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, USA $u Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA $u Psychiatric and Neurodevelopmental Genetics Unit (PNGU), Massachusetts General Hospital, Boston, MA, USA
700    1_
$a Stefansson, Hreinn $u deCODE Genetics/Amgen, Reykjavik, Iceland
700    1_
$a Stefansson, Kari $u deCODE Genetics/Amgen, Reykjavik, Iceland $u Faculty of Medicine, University of Iceland, Reykjavik, Iceland
700    1_
$a Stordal, Eystein $u Department of Psychiatry, Hospital Namsos, Namsos, Norway $u Department of Neuroscience, Norges Teknisk Naturvitenskapelige Universitet Fakultet for Naturvitenskap og Teknologi, Trondheim, Norway
700    1_
$a Streit, Fabian $u Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany
700    1_
$a Sullivan, Patrick F $u Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden $u Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA $u Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
700    1_
$a Turecki, Gustavo $u Department of Psychiatry, McGill University, Montreal, Quebec, Canada
700    1_
$a Vaaler, Arne E $u Department of Psychiatry, Sankt Olavs Hospital Universitetssykehuset i Trondheim, Trondheim, Norway
700    1_
$a Vieta, Eduard $u Clinical Institute of Neuroscience, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Spain
700    1_
$a Vincent, John B $u Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
700    1_
$a Waldman, Irwin D $u Department of Psychology, Emory University, Atlanta, GA, USA
700    1_
$a Weickert, Thomas W $u Neuroscience Research Australia, Sydney, New South Wales, Australia $u School of Psychiatry, University of New South Wales, Sydney, New South Wales, Australia $u Department of Neuroscience, SUNY Upstate Medical University, Syracuse, NY, USA
700    1_
$a Werge, Thomas $u iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark $u Institute of Biological Psychiatry, Mental Health Services, Copenhagen University Hospital, Copenhagen, Denmark $u Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark $u Center for GeoGenetics, GLOBE Institute, University of Copenhagen, Copenhagen, Denmark
700    1_
$a Wray, Naomi R $u Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia $u Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia
700    1_
$a Zwart, John-Anker $u Institute of Clinical Medicine, University of Oslo, Oslo, Norway $u K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway $u Department of Research, Innovation and Education, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway
700    1_
$a Biernacka, Joanna M $u Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA $u Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA
700    1_
$a Nurnberger, John I $u Psychiatry, Indiana University School of Medicine, Indianapolis, IN, USA
700    1_
$a Cichon, Sven $u Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany $u Institute of Neuroscience and Medicine (INM-1), Research Centre Jülich, Jülich, Germany $u Department of Biomedicine, University of Basel, Basel, Switzerland $u Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland
700    1_
$a Edenberg, Howard J $u Department of Medical and Molecular Genetics, Indiana University, Indianapolis, IN, USA $u Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, USA
700    1_
$a Stahl, Eli A $u Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA $u Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA $u Medical and Population Genetics, Broad Institute, Cambridge, MA, USA
700    1_
$a McQuillin, Andrew $u Division of Psychiatry, University College London, London, UK
700    1_
$a Di Florio, Arianna $u Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK $u Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
700    1_
$a Ophoff, Roel A $u Department of Psychiatry and Biobehavioral Science, Semel Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA $u Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA, USA $u Department of Psychiatry, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands $u Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA
700    1_
$a Andreassen, Ole A $u Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway. ole.andreassen@medisin.uio.no $u NORMENT, University of Oslo, Oslo, Norway. ole.andreassen@medisin.uio.no
710    2_
$a HUNT All-In Psychiatry
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$w MED00003458 $t Nature genetics $x 1546-1718 $g Roč. 53, č. 6 (2021), s. 817-829
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910    __
$a ABA008 $b sig $c sign $y p $z 0
990    __
$a 20211013 $b ABA008
991    __
$a 20211026133612 $b ABA008
999    __
$a ok $b bmc $g 1714643 $s 1146193
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2021 $b 53 $c 6 $d 817-829 $e 20210517 $i 1546-1718 $m Nature genetics $n Nat Genet $x MED00003458
GRA    __
$a U01 MH085520 $p NIMH NIH HHS $2 United States
GRA    __
$a U01 MH094421 $p NIMH NIH HHS $2 United States
GRA    __
$a U01 MH109528 $p NIMH NIH HHS $2 United States
GRA    __
$a R01 MH119243 $p NIMH NIH HHS $2 United States
GRA    __
$a S10 OD018522 $p NIH HHS $2 United States
GRA    __
$a S10 OD026880 $p NIH HHS $2 United States
LZP    __
$a Pubmed-20211013

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