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Consensus guidelines for the definition, detection and interpretation of immunogenic cell death
L. Galluzzi, I. Vitale, S. Warren, S. Adjemian, P. Agostinis, AB. Martinez, TA. Chan, G. Coukos, S. Demaria, E. Deutsch, D. Draganov, RL. Edelson, SC. Formenti, J. Fucikova, L. Gabriele, US. Gaipl, SR. Gameiro, AD. Garg, E. Golden, J. Han, KJ....
Language English Country Great Britain
Document type Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S., Review
Grant support
P30 CA008748
NCI NIH HHS - United States
NLK
BioMedCentral Open Access
from 2013
Directory of Open Access Journals
from 2013
Free Medical Journals
from 2013
PubMed Central
from 2013
Europe PubMed Central
from 2013
ProQuest Central
from 2013-05-01
Open Access Digital Library
from 2013-01-01
Open Access Digital Library
from 2013-01-01
Health & Medicine (ProQuest)
from 2013-05-01
ROAD: Directory of Open Access Scholarly Resources
from 2013
- MeSH
- Immunogenic Cell Death genetics MeSH
- Consensus MeSH
- Humans MeSH
- Molecular Biology methods MeSH
- Guidelines as Topic MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
- Research Support, N.I.H., Extramural MeSH
- Research Support, U.S. Gov't, Non-P.H.S. MeSH
Cells succumbing to stress via regulated cell death (RCD) can initiate an adaptive immune response associated with immunological memory, provided they display sufficient antigenicity and adjuvanticity. Moreover, multiple intracellular and microenvironmental features determine the propensity of RCD to drive adaptive immunity. Here, we provide an updated operational definition of immunogenic cell death (ICD), discuss the key factors that dictate the ability of dying cells to drive an adaptive immune response, summarize experimental assays that are currently available for the assessment of ICD in vitro and in vivo, and formulate guidelines for their interpretation.
Calidi Biotherapeutics San Diego California USA
Candiolo Cancer Institute FPO IRCCS Candiolo Italy
Caryl and Israel Englander Institute for Precision Medicine New York City New York USA
Center of Clinical Investigations in Biotherapies of Cancer 1428 Villejuif France
Centre de Recherche du Centre Hospitalier de l'Université de Montréal Montréal Quebec City Canada
Comprehensive Cancer Center Helsinki University Hospital Helsinki Finland
Comprehensive Cancer Center Yale University School of Medicine New Haven Connecticut USA
Department of Bioengineering University of Pittsburgh School of Medicine Pittsburgh Pennsylvania USA
Department of Biomedical Molecular Biology Ghent University Ghent Belgium
Department of Dermatology Yale School of Medicine New Haven Connecticut USA
Department of Immunology University of Pittsburgh School of Medicine Pittsburgh Pennsylvania USA
Department of Medical Biology University of Tromsø Tromsø Norway
Department of Medicine Memorial Sloan Kettering Cancer Center New York City New York USA
Department of Medicine Weill Cornell Medical College New York City New York USA
Department of Oncology and Molecular Medicine Istituto Superiore di Sanità Rome Italy
Department of Oncology University of Melbourne Parkville Victoria Australia
Department of Oncology University of Torino Torino Italy
Department of Radiation Oncology Gustave Roussy Cancer Campus Villejuif France
Department of Radiation Oncology Weill Cornell Medical College New York City New York USA
Department of Surgery University of Pittsburgh School of Medicine Pittsburgh Pennsylvania USA
Department of Surgery UT Southwestern Medical Center Dallas Texas USA
Division of Radiotherapy and Imaging The Institute of Cancer Research London UK
Division of Surgical Oncology Massachusetts General Hospital Boston Massachusetts USA
Equipe 11 labellisée Ligue contre le Cancer Centre de Recherche des Cordeliers Paris France
Equipe labellisée par la Ligue contre le cancer Gustave Roussy Villejuif France
ESSA Pharmaceuticals South San Francisco California USA
Faculté de Pharmacie de l'Université de Montréal Montréal Quebec City Canada
Faculty of Medicine University of Paris Sud Paris Saclay Le Kremlin Bicêtre France
Gustave Roussy Comprehensive Cancer Institute Villejuif France
Hematology and Cell Therapy Clinica Universidad de Navarra Pamplona Spain
Humanitas Clinical and Research Center IRCCS Rozzano Italy
Humanitas University Department of Biomedical Sciences Pieve Emanuele Milan Italy
IIGM Italian Institute for Genomic Medicine c o IRCSS Candiolo Torino Italy
Immun Onkologisches Zentrum Köln Cologne Germany
Institut du Cancer de Montréal Montréal Quebec City Canada
Interdepartmental Research Center of Molecular Biotechnology University of Torino Torino Italy
iRepertoire Inc Huntsville Alabama USA
Istituto di Patologia Generale Università Cattolica del Sacro Cuore Rome Italy
Ludwig Collaborative and Swim Across America Laboratory MSKCC New York City New York USA
McMaster University Hamilton Ontario Canada
Merck and Co Inc Kenilworth New Jersey USA
Methusalem program Ghent University Ghent Belgium
NanoString Technologies Seattle Washington USA
Parker Institute for Cancer Immunotherapy MSKCC New York City New York USA
Pôle de Biologie Hôpital Européen Georges Pompidou AP HP Paris France
Refuge Biotechnologies Menlo Park California USA
Replimune Inc Woburn Massachusetts USA
Sandra and Edward Meyer Cancer Center New York City New York USA
SIRIC SOCRATES DHU Torino Faculté de Medecine Université Paris Saclay Kremlin Bicêtre France
Sorbonne Université Paris France
Suzhou Institute for Systems Medicine Chinese Academy of Medical Sciences Suzhou China
The Institute of Cancer Research London UK
Universitätsklinikum Erlangen Erlangen Germany
Université de Paris Paris France
University of Manchester NIHR Manchester Biomedical Research Centre Christie Hospital Manchester UK
UOSD Immunology and Immunotherapy Unit IRCCS Regina Elena National Cancer Institute Rome Italy
VIB Center for Inflammation Research Ghent Belgium
VIB KU Leuven Center for Cancer Biology KU Leuevn Leuven Belgium
References provided by Crossref.org
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