Detail
Article
Online article
FT
Medvik - BMC
  • Something wrong with this record ?

Oculometric behavior assessed by pupil response is altered in adolescent depression

N. Sekaninova, I. Ondrejka, L. Bona Olexova, Z. Visnovcova, M. Mestanik, D. Cesnekova, A. Hamrakova, I. Tonhajzerova

. 2019 ; 68 (Suppl 3) : S325-S338. [pub] 20191220
. 2019 ; () : S325-S338.

Language English Country Czech Republic

Document type Journal Article

Persistent link   https://www.medvik.cz/link/bmc21028183

Oculometric behaviour assessed by pupil response provides important information about central autonomic activity and emotional regulation. However, studies regarding pupil response to emotional stimuli in adolescent depression are rare. We aimed to study emotional-linked pupil response in adolescent depression. Twenty depressive adolescents (average age: 15.4+/-1.2 years) and 20 age/gender-matched healthy subjects were examined. Average pupil diameter assessed by eye-tracking and pupillary light reflex were evaluated during protocol - baseline, free-view task, recovery phase. Regarding right eye, significantly greater initial pupil diameter and pupil dilation to positive pictures free-viewing (p=0.013, p=0.031, respectively), significantly slower average and maximum constriction velocity in baseline and positive pictures free-viewing (p=0.036, p=0.050, p=0.021, p=0.015, respectively), significantly slower maximum constriction velocity in recovery phase (p=0.045), and significantly faster average dilation velocity in negative pictures free-viewing (p=0.042) were observed in depressive group. Regarding left eye, significantly lower constriction percentual change in negative pictures free-viewing (p=0.044) and significantly greater baseline pupil diameter and pupil diameter at the peak of constriction in positive vs. negative pictures free-viewing (p=0.002, p=0.015, respectively) were observed in depressive group. Our study revealed discrete central autonomic dysregulation - parasympathetic hypoactivity associated with relative sympathetic dominance influenced by impairments in emotional processing already in adolescent depression.

References provided by Crossref.org

Bibliography, etc.

Literatura

000      
00000naa a2200000 a 4500
001      
bmc21028183
003      
CZ-PrNML
005      
20220328170715.0
007      
ta
008      
211105s2019 xr a f 000 0|eng||
009      
AR
024    7_
$a 10.33549/physiolres.934359 $2 doi
035    __
$a (PubMed)31928050
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xr
100    1_
$a Sekaninová, Nikola $7 xx0257292 $u Department of Physiology and Biomedical Center Martin, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak Republic $u Biomedical Center Martin, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak Republic
245    10
$a Oculometric behavior assessed by pupil response is altered in adolescent depression / $c N. Sekaninova, I. Ondrejka, L. Bona Olexova, Z. Visnovcova, M. Mestanik, D. Cesnekova, A. Hamrakova, I. Tonhajzerova
504    __
$a Literatura
520    9_
$a Oculometric behaviour assessed by pupil response provides important information about central autonomic activity and emotional regulation. However, studies regarding pupil response to emotional stimuli in adolescent depression are rare. We aimed to study emotional-linked pupil response in adolescent depression. Twenty depressive adolescents (average age: 15.4+/-1.2 years) and 20 age/gender-matched healthy subjects were examined. Average pupil diameter assessed by eye-tracking and pupillary light reflex were evaluated during protocol - baseline, free-view task, recovery phase. Regarding right eye, significantly greater initial pupil diameter and pupil dilation to positive pictures free-viewing (p=0.013, p=0.031, respectively), significantly slower average and maximum constriction velocity in baseline and positive pictures free-viewing (p=0.036, p=0.050, p=0.021, p=0.015, respectively), significantly slower maximum constriction velocity in recovery phase (p=0.045), and significantly faster average dilation velocity in negative pictures free-viewing (p=0.042) were observed in depressive group. Regarding left eye, significantly lower constriction percentual change in negative pictures free-viewing (p=0.044) and significantly greater baseline pupil diameter and pupil diameter at the peak of constriction in positive vs. negative pictures free-viewing (p=0.002, p=0.015, respectively) were observed in depressive group. Our study revealed discrete central autonomic dysregulation - parasympathetic hypoactivity associated with relative sympathetic dominance influenced by impairments in emotional processing already in adolescent depression.
650    _2
$a mladiství $7 D000293
650    _2
$a autonomní nervový systém $x patofyziologie $7 D001341
650    _2
$a studie případů a kontrol $7 D016022
650    _2
$a depresivní porucha unipolární $x patofyziologie $x psychologie $7 D003865
650    _2
$a emoce $x fyziologie $7 D004644
650    _2
$a ženské pohlaví $7 D005260
650    _2
$a lidé $7 D006801
650    _2
$a mužské pohlaví $7 D008297
650    _2
$a reflex pupilární $7 D012025
655    _2
$a časopisecké články $7 D016428
700    1_
$a Ondrejka, Igor $7 xx0105387 $u Psychiatric Clinic, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, University Hospital Martin, Martin, Slovak Republic
700    1_
$a Olexová, Lucia $7 xx0257396 $u Department of Physiology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak Republic $u Biomedical Center Martin, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak Republic
700    1_
$a Višňovcová, Zuzana $7 xx0257400 $u Biomedical Center Martin, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak Republic
700    1_
$a Mešťaník, Michal $7 xx0248443 $u Department of Physiology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak Republic $u Biomedical Center Martin, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak Republic
700    1_
$a Cesneková, Dana, $d 1990- $7 xx0267115 $u Psychiatric Clinic, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, University Hospital Martin, Martin, Slovak Republic
700    1_
$a Hamráková, Andrea, $d 1993- $7 xx0267114 $u Department of Physiology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak Republic $u Psychiatric Clinic, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, University Hospital Martin, Martin, Slovak Republic
700    1_
$a Tonhajzerová, Ingrid $7 xx0105807 $u Department of Physiology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak Republic $u Biomedical Center Martin, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak Republic
773    0_
$w MED00003824 $t Physiological research $x 1802-9973 $g Roč. 68, Suppl 3 (2019), s. S325-S338
773    0_
$t Proceedings of the ... Physiological days $g (2019), s. S325-S338 $w MED00183838
856    41
$u https://pubmed.ncbi.nlm.nih.gov/31928050 $y Pubmed
910    __
$a ABA008 $b A 4120 $c 266 $y p $z 0
990    __
$a 20211105 $b ABA008
991    __
$a 20220328170712 $b ABA008
999    __
$a ok $b bmc $g 1735504 $s 1148728
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2019 $b 68 $c Suppl 3 $d S325-S338 $e 20191220 $i 1802-9973 $m Physiological research $n Physiol. Res. (Print) $x MED00003824
BMC    __
$a 2019 $d S325-S338 $m Proceedings of the ... Physiological days $x MED00183838
LZP    __
$b NLK118 $a Pubmed-20211105

Find record

Citation metrics

Archiving options