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The proteins of SARS- CoV-2 and their functions

Zohreh Taheri Kangarshahi, Shermin Lak, Mona Ghadam, Nasrin Motamed, Sorosh Sardari, Samin Rahimi

. 2021 ; 90 (4) : 172-190. [pub] 20211203

Language Czech Country Czech Republic

Persistent link   https://www.medvik.cz/link/bmc22000330

Coronavirus 2 (SARS- CoV-2) leads to Coronavirus disease 2019, is recognized as a lethal epidemic in 2020. SARS-CoV-2 is an enveloped, non-segmented, positive sense RNA virus that belongs to the beta-corona family of viruses. The genome of this virus is about 30 kb representing 16 non-structural proteins (Nsp1-16), four structural proteins (N, M, E, S) and nine accessory proteins are encoded by its genome, which are involved in survival and pathogenesis the viruses. In order to produce medicines and vaccines for SARS-CoV-2, it is essential to fully understand the genomic structure of the virus and function of its proteins. This review collects and investigates the functional properties of SARS-CoV-2 proteins that have been reported to date.

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