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Can baicalein become a new drug for covid-19?

Jiří Patočka, Zdeňka Navrátilová, Kamil Kuča, Patrik Olekšák, Uday Kumar Killi

. 2021 ; 90 (4) : 198-207. [pub] 20211203

Jazyk čeština Země Česko

Typ dokumentu práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/bmc22000332

The ongoing coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a global health crisis. Flavon baicalein, a major bioactive molecule of Scutellaria baicalensis, inhibits the replication of SARS-CoV-2 which causes severe acute respiratory syndrome in humans. Animal experiments show that baicalein has the character of a broad-spectrum coronavirus drug. It is non-toxic and can inhibit SARS-CoV-2-induced damage. Baicalein may therefore be a promising therapeutic drug for the treatment of COVID-19.

Citace poskytuje Crossref.org

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