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Heterogeneous associative plasticity in the auditory cortex induced by fear learning - novel insight into the classical conditioning paradigm

O. Zelenka, O. Novak, A. Brunova, J. Syka

. 2021 ; 70 (3) : 447-460. [pub] 20210512

Jazyk angličtina Země Česko

Typ dokumentu časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/bmc22000858

We used two-photon calcium imaging with single-cell and cell-type resolution. Fear conditioning induced heterogeneous tuning shifts at single-cell level in the auditory cortex, with shifts both to CS+ frequency and to the control CS- stimulus frequency. We thus extend the view of simple expansion of CS+ tuned regions. Instead of conventional freezing reactions only, we observe selective orienting responses towards the conditioned stimuli. The orienting responses were often followed by escape behavior.

Citace poskytuje Crossref.org

Bibliografie atd.

Literatura

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