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A scientific journey from discovery to validation of efficacy in cancer patients: HAMLET and alpha1-oleate

JCS. Ho, I. Ambite, KH. Mok, M. Babjuk, C. Svanborg

. 2021 ; 8 (5) : 1974278. [pub] 20210930

Language English Country United States

Document type Journal Article

Persistent link   https://www.medvik.cz/link/bmc22001662

The protein-lipid complex alpha1-oleate, derived from HAMLET (Human Alpha-lactalbumin Made LEthal to Tumor cells), is identified as a molecular entity with significant therapeutic potential. Structural characterization of the complex and results of a successful placebo-controlled clinical trial are presented.

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