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TROPHY registry - status report

UW. Thomale, C. Auer, P. Spennato, A. Schaumann, P. Behrens, S. Gorelyshev, E. Bogoslovskaia, A. Shulaev, A. Kabanian, A. Seliverstov, A. Alexeev, O. Ozgural, G. Kahilogullari, M. Schuhmann, R. Jimenez-Guerra, N. Wittayanakorn, A. Sukharev, J....

. 2021 ; 37 (11) : 3549-3554. [pub] 20210629

Jazyk angličtina Země Německo

Typ dokumentu časopisecké články, multicentrická studie, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/bmc22003279

INTRODUCTION: The TROPHY registry has been established to conduct an international multicenter prospective data collection on the surgical management of neonatal intraventricular hemorrhage (IVH)-related hydrocephalus to possibly contribute to future guidelines. The registry allows comparing the techniques established to treat hydrocephalus, such as external ventricular drainage (EVD), ventricular access device (VAD), ventricular subgaleal shunt (VSGS), and neuroendoscopic lavage (NEL). This first status report of the registry presents the results of the standard of care survey of participating centers assessed upon online registration. METHODS: On the standard of treatment forms, each center indicated the institutional protocol of interventions performed for neonatal post-hemorrhagic hydrocephalus (nPHH) for a time period of 2 years (Y1 and Y2) before starting the active participation in the registry. In addition, the amount of patients enrolled so far and allocated to a treatment approach are reported. RESULTS: According to the standard of treatment forms completed by 56 registered centers, fewer EVDs (Y1 55% Y2 46%) were used while more centers have implemented NEL (Y1 39%; Y2 52%) to treat nPHH. VAD (Y1 66%; Y2 66%) and VSGS (Y1 42%; Y2 41%) were used at a consistent rate during the 2 years. The majority of the centers used at least two different techniques to treat nPHH (43%), while 27% used only one technique, 21% used three, and 7% used even four different techniques. Patient data of 110 infants treated surgically between 9/2018 and 2/2021 (13% EVD, 15% VAD, 30% VSGS, and 43% NEL) were contributed by 29 centers. CONCLUSIONS: Our results emphasize the varying strategies used for the treatment of nPHH. The international TROPHY registry has entered into a phase of growing patient recruitment. Further evaluation will be performed and published according to the registry protocol.

Division of Pediatric Neurosurgery Kepler Universitätsklinikum Linz Austria

Neonatal Neurosurgery National Institute of Perinatology Mexico City Mexico

Neurosurgery Amsterdam University Medical Centres Amsterdam Netherlands

Neurosurgery Ankara University Ankara Turkey

Neurosurgery Centro Hospitalar Universitário São João Porto Portugal

Neurosurgery Damietta Specialized Hospital Damietta Egypt

Neurosurgery Heinrich Heine University Duesseldorf Germany

Neurosurgery Hospital La Paz Madrid Spain

Neurosurgery Marienhospital Osnabrück Germany

Neurosurgery Masaryk Hospital Usti Nad Labem Czech Republic

Neurosurgery Saarland University Hospital Homburg Saarland Germany

Neurosurgery Universitätskinderspital Beider Basel Basel Switzerland

Neurosurgery University Hospital and Faculty of Medicine in Pilsen Charles University Pilsen Czech Republic

Neurosurgery University Medicine Greifswald Greifswald Germany

Neurosurgery Virgen del Rocio Hospital Seville Spain

Neurosurgery Volyn Regional Pediatric Hospital Lutsk Ukraine

Pediatric Neurosurgery Ann and Robert H Lurie Children's Hospital of Chicago Chicago USA

Pediatric Neurosurgery AORN Santobono Pausilipon Naples Italy

Pediatric Neurosurgery Campus Virchow Klinikum Charité Universitätsmedizin Berlin Augustenburger Platz 1 13353 Berlin Germany

Pediatric Neurosurgery Chelyabinsk Regional Children's Clinical Hospital Chelyabinsk Russia

Pediatric Neurosurgery Children's Regional Hospital Krasnodar Russia

Pediatric Neurosurgery Children's Republic Clinical Hospital Kazan Russia

Pediatric Neurosurgery Federal University of Sao Paulo Sao Paulo Brazil

Pediatric Neurosurgery Heidelberg University Hospital Heidelberg Germany

Pediatric Neurosurgery Iaso Childrens Hospital Athens Greece

Pediatric Neurosurgery Kemerovo Regional Pediatric Hospital Kemerovo Russia

Pediatric Neurosurgery Moscow Bashlyaeva Pediatric Hospital Moscow Russia

Pediatric Neurosurgery Regional Children Hospital Yekaterinburg Russia

Pediatric Neurosurgery Sick Children Hospital University of Toronto Toronto Canada

Pediatric Neurosurgery Surgut Clinical Perinatal Center Surgut Russia

Pediatric Neurosurgery Tel Aviv Medical Center Tel Aviv Israel

Pediatric Neurosurgery University Hospital of Tübingen Tubingen Germany

Pediatric Neurosurgery University Medical Center Göttingen Gottingen Germany

Surgery Queen Sirikit National Institute of Child Health Bangkok Thailand

Citace poskytuje Crossref.org

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