• Je něco špatně v tomto záznamu ?

Clinical and radiological factors predicting stroke outcome after successful mechanical intervention in anterior circulation

T. Peisker, P. Vaško, P. Mikulenka, D. Lauer, B. Kožnar, J. Sulženko, F. Roháč, D. Kučera, D. Girsa, K. Kremeňová, P. Widimský, I. Štětkářová

. 2022 ; 24 (Suppl B) : B48-B52. [pub] 20220330

Jazyk angličtina Země Velká Británie

Typ dokumentu časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/bmc22017494

The recanalization effect of large-vessel occlusion (LVO) in anterior circulation is well documented but only some patients benefit from endovascular treatment. We analysed clinical and radiological factors determining clinical outcome after successful mechanical intervention. We included 146 patients from the Prague 16 study enrolled from September 2012 to December 2020, who had initial CT/CTA examination and achieved good recanalization status after mechanical intervention (TICI 2b-3). One hundred and six (73%) patients achieved a good clinical outcome (modified Rankin Scale 0-2 in 3 months). It was associated with age, leptomeningeal collaterals (LC), onset to intervention time, ASPECTS, initial NIHSS, and leukoaraiosis (LA) in univariate analysis. The regression model identified good collateral status [odds ratio (OR) 5.00, 95% confidence interval (CI) 1.91-13.08], late thrombectomy (OR 0.24, 95% CI 0.09-0.65), LA (OR 0.44, 95% CI 0.19-1.00), ASPECTS (OR 1.45, 95% CI 1.08-1.95), and NIHSS score (OR 0.86, 95% CI 0.78-0.95) as independent outcome determinants. In the late thrombectomy subgroup, 14 out of 33 patients (42%) achieved a favourable clinical outcome, none of whom with poor collateral status. The presence of LC and absence of LA predicts a good outcome in acute stroke patients after successful recanalization of LVO in anterior circulation. Late thrombectomy was associated with higher rate of unfavourable clinical outcome. Nevertheless, collateral status in this subgroup was validated as a reliable selection criterion.

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc22017494
003      
CZ-PrNML
005      
20220720100244.0
007      
ta
008      
220718s2022 xxk f 000 0|eng||
009      
AR
024    7_
$a 10.1093/eurheartjsupp/suac010 $2 doi
035    __
$a (PubMed)35370500
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xxk
100    1_
$a Peisker, Tomáš $u Department of Neurology, Third Faculty of Medicine, Charles University and University Hospital Kralovske Vinohrady, Šrobárova 50, 100 34 Praha, Prague, Czech Republic
245    10
$a Clinical and radiological factors predicting stroke outcome after successful mechanical intervention in anterior circulation / $c T. Peisker, P. Vaško, P. Mikulenka, D. Lauer, B. Kožnar, J. Sulženko, F. Roháč, D. Kučera, D. Girsa, K. Kremeňová, P. Widimský, I. Štětkářová
520    9_
$a The recanalization effect of large-vessel occlusion (LVO) in anterior circulation is well documented but only some patients benefit from endovascular treatment. We analysed clinical and radiological factors determining clinical outcome after successful mechanical intervention. We included 146 patients from the Prague 16 study enrolled from September 2012 to December 2020, who had initial CT/CTA examination and achieved good recanalization status after mechanical intervention (TICI 2b-3). One hundred and six (73%) patients achieved a good clinical outcome (modified Rankin Scale 0-2 in 3 months). It was associated with age, leptomeningeal collaterals (LC), onset to intervention time, ASPECTS, initial NIHSS, and leukoaraiosis (LA) in univariate analysis. The regression model identified good collateral status [odds ratio (OR) 5.00, 95% confidence interval (CI) 1.91-13.08], late thrombectomy (OR 0.24, 95% CI 0.09-0.65), LA (OR 0.44, 95% CI 0.19-1.00), ASPECTS (OR 1.45, 95% CI 1.08-1.95), and NIHSS score (OR 0.86, 95% CI 0.78-0.95) as independent outcome determinants. In the late thrombectomy subgroup, 14 out of 33 patients (42%) achieved a favourable clinical outcome, none of whom with poor collateral status. The presence of LC and absence of LA predicts a good outcome in acute stroke patients after successful recanalization of LVO in anterior circulation. Late thrombectomy was associated with higher rate of unfavourable clinical outcome. Nevertheless, collateral status in this subgroup was validated as a reliable selection criterion.
655    _2
$a časopisecké články $7 D016428
700    1_
$a Vaško, Peter $u Department of Neurology, Third Faculty of Medicine, Charles University and University Hospital Kralovske Vinohrady, Šrobárova 50, 100 34 Praha, Prague, Czech Republic
700    1_
$a Mikulenka, Petr $u Department of Neurology, Third Faculty of Medicine, Charles University and University Hospital Kralovske Vinohrady, Šrobárova 50, 100 34 Praha, Prague, Czech Republic
700    1_
$a Lauer, David $u Department of Neurology, Third Faculty of Medicine, Charles University and University Hospital Kralovske Vinohrady, Šrobárova 50, 100 34 Praha, Prague, Czech Republic
700    1_
$a Kožnar, Boris $u Department of Cardiology, Third Faculty of Medicine, Charles University and University Hospital Kralovske Vinohrady, Šrobárova 50, 100 34 Praha, Prague, Czech Republic
700    1_
$a Sulženko, Jakub $u Department of Cardiology, Third Faculty of Medicine, Charles University and University Hospital Kralovske Vinohrady, Šrobárova 50, 100 34 Praha, Prague, Czech Republic
700    1_
$a Roháč, Filip $u Department of Cardiology, Third Faculty of Medicine, Charles University and University Hospital Kralovske Vinohrady, Šrobárova 50, 100 34 Praha, Prague, Czech Republic
700    1_
$a Kučera, Dušan $u Department of Cardiology, Third Faculty of Medicine, Charles University and University Hospital Kralovske Vinohrady, Šrobárova 50, 100 34 Praha, Prague, Czech Republic
700    1_
$a Girsa, David $u Department of Radiology, Third Faculty of Medicine, Charles University and University Hospital Kralovske Vinohrady, Šrobárova 50, 100 34 Praha, Prague, Czech Republic
700    1_
$a Kremeňová, Karin $u Department of Radiology, Third Faculty of Medicine, Charles University and University Hospital Kralovske Vinohrady, Šrobárova 50, 100 34 Praha, Prague, Czech Republic
700    1_
$a Widimský, Petr $u Department of Cardiology, Third Faculty of Medicine, Charles University and University Hospital Kralovske Vinohrady, Šrobárova 50, 100 34 Praha, Prague, Czech Republic
700    1_
$a Štětkářová, Ivana $u Department of Neurology, Third Faculty of Medicine, Charles University and University Hospital Kralovske Vinohrady, Šrobárova 50, 100 34 Praha, Prague, Czech Republic
773    0_
$w MED00005247 $t European heart journal supplements : journal of the European Society of Cardiology $x 1520-765X $g Roč. 24, Suppl B (2022), s. B48-B52
856    41
$u https://pubmed.ncbi.nlm.nih.gov/35370500 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y - $z 0
990    __
$a 20220718 $b ABA008
991    __
$a 20220720100239 $b ABA008
999    __
$a ind $b bmc $g 1816617 $s 1168736
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2022 $b 24 $c Suppl B $d B48-B52 $e 20220330 $i 1520-765X $m European heart journal supplements $n Eur Heart J Suppl $x MED00005247
LZP    __
$a Pubmed-20220718

Najít záznam

Citační ukazatele

Možnosti archivace