-
Je něco špatně v tomto záznamu ?
Clinical prediction of laboratory-confirmed influenza in adults with influenza-like illness in primary care. A randomized controlled trial secondary analysis in 15 European countries
D. Ouchi, A. García-Sangenís, A. Moragas, AW. van der Velden, TJ. Verheij, CC. Butler, E. Bongard, S. Coenen, J. Cook, NA. Francis, M. Godycki-Cwirko, PT. Lundgren, C. Lionis, R. Radzeviciene Jurgute, S. Chlabicz, A. De Sutter, HC. Bucher, B....
Jazyk angličtina Země Velká Británie
Typ dokumentu časopisecké články, randomizované kontrolované studie, práce podpořená grantem
NLK
Free Medical Journals
od 1996 do Před 1 rokem
Open Access Digital Library
od 1996-01-01
PubMed
34611715
DOI
10.1093/fampra/cmab122
Knihovny.cz E-zdroje
- MeSH
- chřipka lidská * diagnóza epidemiologie MeSH
- dospělí MeSH
- horečka MeSH
- kašel MeSH
- klinické laboratorní techniky MeSH
- lidé středního věku MeSH
- lidé MeSH
- primární zdravotní péče MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- randomizované kontrolované studie MeSH
BACKGROUND: Clinical findings do not accurately predict laboratory diagnosis of influenza. Early identification of influenza is considered useful for proper management decisions in primary care. OBJECTIVE: We evaluated the diagnostic value of the presence and the severity of symptoms for the diagnosis of laboratory-confirmed influenza infection among adults presenting with influenza-like illness (ILI) in primary care. METHODS: Secondary analysis of patients with ILI who participated in a clinical trial from 2015 to 2018 in 15 European countries. Patients rated signs and symptoms as absent, minor, moderate, or major problem. A nasopharyngeal swab was taken for microbiological identification of influenza and other microorganisms. Models were generated considering (i) the presence of individual symptoms and (ii) the severity rating of symptoms. RESULTS: A total of 2,639 patients aged 18 or older were included in the analysis. The mean age was 41.8 ± 14.7 years, and 1,099 were men (42.1%). Influenza was microbiologically confirmed in 1,337 patients (51.1%). The area under the curve (AUC) of the model for the presence of any of seven symptoms for detecting influenza was 0.66 (95% confidence interval [CI]: 0.65-0.68), whereas the AUC of the symptom severity model, which included eight variables-cough, fever, muscle aches, sweating and/or chills, moderate to severe overall disease, age, abdominal pain, and sore throat-was 0.70 (95% CI: 0.69-0.72). CONCLUSION: Clinical prediction of microbiologically confirmed influenza in adults with ILI is slightly more accurate when based on patient reported symptom severity than when based on the presence or absence of symptoms.
Clinic of Social and Family Medicine Faculty of Medicine University of Crete Crete Greece
Department of Family Medicine Medical University of Bialystok Bialystok Poland
Department of General Practice 1st Faculty of Medicine Charles University Prague Czech Republic
Department of Public Health General Practice University of Southern Denmark Odense Denmark
Drug Research Centre Balatonfüred Hungary
JSC Mano Seimos Gydytojas Klaipeda Lithuania
Laboratory of Clinical Microbiology Antwerp University Hospital Edegem Belgium
Nuffield Department of Primary Health Care Sciences University of Oxford Oxford United Kingdom
Primary Care Research Centre University of Southampton Southampton United Kingdom
Universitat Autònoma de Barcelona Bellaterra Spain
University Institute in Primary Care Research Jordi Gol i Gurina Barcelona Spain
Citace poskytuje Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc22018298
- 003
- CZ-PrNML
- 005
- 20220804134702.0
- 007
- ta
- 008
- 220720s2022 xxk f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.1093/fampra/cmab122 $2 doi
- 035 __
- $a (PubMed)34611715
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a xxk
- 100 1_
- $a Ouchi, Dan $u University Institute in Primary Care Research Jordi Gol i Gurina, Barcelona, Spain $u Universitat Autònoma de Barcelona, Bellaterra (Cerdanyola del Vallès), Spain
- 245 10
- $a Clinical prediction of laboratory-confirmed influenza in adults with influenza-like illness in primary care. A randomized controlled trial secondary analysis in 15 European countries / $c D. Ouchi, A. García-Sangenís, A. Moragas, AW. van der Velden, TJ. Verheij, CC. Butler, E. Bongard, S. Coenen, J. Cook, NA. Francis, M. Godycki-Cwirko, PT. Lundgren, C. Lionis, R. Radzeviciene Jurgute, S. Chlabicz, A. De Sutter, HC. Bucher, B. Seifert, B. Kovács, M. de Paor, PD. Sundvall, R. Aabenhus, NJ. Harbin, G. Ieven, H. Goossens, M. Lindbæk, L. Bjerrum, C. Llor
- 520 9_
- $a BACKGROUND: Clinical findings do not accurately predict laboratory diagnosis of influenza. Early identification of influenza is considered useful for proper management decisions in primary care. OBJECTIVE: We evaluated the diagnostic value of the presence and the severity of symptoms for the diagnosis of laboratory-confirmed influenza infection among adults presenting with influenza-like illness (ILI) in primary care. METHODS: Secondary analysis of patients with ILI who participated in a clinical trial from 2015 to 2018 in 15 European countries. Patients rated signs and symptoms as absent, minor, moderate, or major problem. A nasopharyngeal swab was taken for microbiological identification of influenza and other microorganisms. Models were generated considering (i) the presence of individual symptoms and (ii) the severity rating of symptoms. RESULTS: A total of 2,639 patients aged 18 or older were included in the analysis. The mean age was 41.8 ± 14.7 years, and 1,099 were men (42.1%). Influenza was microbiologically confirmed in 1,337 patients (51.1%). The area under the curve (AUC) of the model for the presence of any of seven symptoms for detecting influenza was 0.66 (95% confidence interval [CI]: 0.65-0.68), whereas the AUC of the symptom severity model, which included eight variables-cough, fever, muscle aches, sweating and/or chills, moderate to severe overall disease, age, abdominal pain, and sore throat-was 0.70 (95% CI: 0.69-0.72). CONCLUSION: Clinical prediction of microbiologically confirmed influenza in adults with ILI is slightly more accurate when based on patient reported symptom severity than when based on the presence or absence of symptoms.
- 650 _2
- $a dospělí $7 D000328
- 650 _2
- $a klinické laboratorní techniky $7 D019411
- 650 _2
- $a kašel $7 D003371
- 650 _2
- $a ženské pohlaví $7 D005260
- 650 _2
- $a horečka $7 D005334
- 650 _2
- $a lidé $7 D006801
- 650 12
- $a chřipka lidská $x diagnóza $x epidemiologie $7 D007251
- 650 _2
- $a mužské pohlaví $7 D008297
- 650 _2
- $a lidé středního věku $7 D008875
- 650 _2
- $a primární zdravotní péče $7 D011320
- 655 _2
- $a časopisecké články $7 D016428
- 655 _2
- $a randomizované kontrolované studie $7 D016449
- 655 _2
- $a práce podpořená grantem $7 D013485
- 700 1_
- $a García-Sangenís, Ana $u University Institute in Primary Care Research Jordi Gol i Gurina, Barcelona, Spain
- 700 1_
- $a Moragas, Ana $u University Institute in Primary Care Research Jordi Gol i Gurina, Barcelona, Spain
- 700 1_
- $a van der Velden, Alike W $u Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, Netherlands
- 700 1_
- $a Verheij, Theo J $u Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, Netherlands
- 700 1_
- $a Butler, Christopher C $u Nuffield Department of Primary Health Care Sciences, University of Oxford, Oxford, United Kingdom $1 https://orcid.org/0000000201023453
- 700 1_
- $a Bongard, Emily $u Nuffield Department of Primary Health Care Sciences, University of Oxford, Oxford, United Kingdom
- 700 1_
- $a Coenen, Samuel $u Centre for General Practice, Department of Family Medicine & Population Health, University of Antwerp, Antwerp, Belgium $1 https://orcid.org/0000000212388052
- 700 1_
- $a Cook, Johanna $u Nuffield Department of Primary Health Care Sciences, University of Oxford, Oxford, United Kingdom
- 700 1_
- $a Francis, Nick A $u Primary Care Research Centre, University of Southampton, Southampton,United Kingdom $1 https://orcid.org/0000000189397312
- 700 1_
- $a Godycki-Cwirko, Maciek $u Centre for Family and Community Medicine, Faculty of Health Sciences, Medical University of Lodz, Lodz, Poland $1 https://orcid.org/0000000292045518
- 700 1_
- $a Lundgren, Pia Touboul $u Département de Santé Publique, Université Côte d'Azur, Centre Hospitalier Universitaire de Nice, Nice, France
- 700 1_
- $a Lionis, Christos $u Clinic of Social and Family Medicine, Faculty of Medicine, University of Crete, Crete, Greece
- 700 1_
- $a Radzeviciene Jurgute, Ruta $u JSC Mano Seimos Gydytojas (My Family Doctor), Klaipeda, Lithuania
- 700 1_
- $a Chlabicz, Sławomir $u Department of Family Medicine, Medical University of Bialystok, Bialystok, Poland
- 700 1_
- $a De Sutter, An $u Centre for Family Medicine UGent, Department of Public Health and Primary Care, Ghent University, Ghent, Belgium
- 700 1_
- $a Bucher, Heiner C $u Basel Institute for Clinical Epidemiology and Biostatistics, Department of Clinical Research, University Hospital Basel and University of Basel, Basel, Switzerland
- 700 1_
- $a Seifert, Bohumil $u Department of General Practice, First Faculty of Medicine, Charles University, Prague, Czech Republic
- 700 1_
- $a Kovács, Bernadett $u Drug Research Centre, Balatonfüred, Hungary
- 700 1_
- $a de Paor, Muireann $u HRB Centre for Primary Care Research, Department of General Practice, Royal College of Surgeons in Ireland (RCSI), Health Research Board Primary Care Clinical Trial Network Ireland, National University of Ireland Galway, Galway, Ireland
- 700 1_
- $a Sundvall, Pär-Daniel $u Research, Education, Development & Innovation Primary Health Care, Region Västra Götaland and Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
- 700 1_
- $a Aabenhus, Rune $u Section and Research Unit of General Practice, Department of Public Health, University of Copenhagen, Copenhagen, Denmark
- 700 1_
- $a Harbin, Nicolay Jonassen $u Antibiotic Centre for Primary Care, Department of General Practice, Institute of Health and Society, University of Oslo, Oslo, Norway
- 700 1_
- $a Ieven, Greet $u Laboratory of Clinical Microbiology, Antwerp, University Hospital, Edegem, Belgium
- 700 1_
- $a Goossens, Herman $u Laboratory of Clinical Microbiology, Antwerp, University Hospital, Edegem, Belgium
- 700 1_
- $a Lindbæk, Morten $u Antibiotic Centre for Primary Care, Department of General Practice, Institute of Health and Society, University of Oslo, Oslo, Norway
- 700 1_
- $a Bjerrum, Lars $u Section and Research Unit of General Practice, Department of Public Health, University of Copenhagen, Copenhagen, Denmark
- 700 1_
- $a Llor, Carl $u University Institute in Primary Care Research Jordi Gol i Gurina, Barcelona, Spain $u Department of Public Health, General Practice, University of Southern Denmark, Odense, Denmark $1 https://orcid.org/000000016644717X
- 773 0_
- $w MED00001760 $t Family practice $x 1460-2229 $g Roč. 39, č. 3 (2022), s. 398-405
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/34611715 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y p $z 0
- 990 __
- $a 20220720 $b ABA008
- 991 __
- $a 20220804134656 $b ABA008
- 999 __
- $a ok $b bmc $g 1822073 $s 1169541
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2022 $b 39 $c 3 $d 398-405 $e 20220528 $i 1460-2229 $m Family practice $n Fam Pract $x MED00001760
- LZP __
- $a Pubmed-20220720
