• Je něco špatně v tomto záznamu ?

Assessment of antibacterial and anti-biofilm effects of zinc ferrite nanoparticles against Klebsiella pneumoniae

RP. Sharma, SD. Raut, VV. Jadhav, RM. Mulani, AS. Kadam, RS. Mane

. 2022 ; 67 (5) : 747-755. [pub] 20220425

Jazyk angličtina Země Spojené státy americké

Typ dokumentu časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/bmc22022928

In response to the emergence of drug resistance and limited therapeutic options, researchers are in action to look for more effective and sustainable antimicrobial practices. Over few years, novel nanoparticles are proving to be potent and promising for effectively dealing with ever- evolving microbial pathogens and diseases. In the present investigation, antibacterial and anti-biofilm efficiencies of zinc ferrite nanoparticles (ZnFe2O4 NPs) are explored against opportunistic pathogens Klebsiella pneumoniae (K. pneumoniae). Results of the present study demonstrate that the ZnFe2O4 NPs endow an excellent antibacterial efficiency with a maximum zone of inhibition i.e.16 mm. The reactive oxygen species (ROS)-induced bacterial damage is caused by the ZnFe2O4 NPs. Subsequently, intracellular cytoplasmic leakage of sugar and protein confirms their ability to disturb the membrane integrity of bacteria. This study also demonstrates the prominent efficiency of ZnFe2O4 NPs in an anti-biofilm study by inhibiting biofilm formation up to 81.76% and reducing mature biofilm up to 56.22% at 75 μg/mL the minimum inhibitory concentration value. Therapeutic possibilities of the ZnFe2O4 NPs in antimicrobial applications are discussed which are helpful to overcome the challenges associated with biofilm infectivity.

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc22022928
003      
CZ-PrNML
005      
20240416152940.0
007      
ta
008      
221007s2022 xxu f 000 0|eng||
009      
AR
024    7_
$a 10.1007/s12223-022-00969-2 $2 doi
035    __
$a (PubMed)35467317
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xxu
100    1_
$a Sharma, Rashmi P $u Department of Biotechnology and Microbiology, Vivekanand Arts, Sardar DalipSingh Commerce And Science College, Aurangabad, M.S, India $1 http://orcid.org/0000000200653779
245    10
$a Assessment of antibacterial and anti-biofilm effects of zinc ferrite nanoparticles against Klebsiella pneumoniae / $c RP. Sharma, SD. Raut, VV. Jadhav, RM. Mulani, AS. Kadam, RS. Mane
520    9_
$a In response to the emergence of drug resistance and limited therapeutic options, researchers are in action to look for more effective and sustainable antimicrobial practices. Over few years, novel nanoparticles are proving to be potent and promising for effectively dealing with ever- evolving microbial pathogens and diseases. In the present investigation, antibacterial and anti-biofilm efficiencies of zinc ferrite nanoparticles (ZnFe2O4 NPs) are explored against opportunistic pathogens Klebsiella pneumoniae (K. pneumoniae). Results of the present study demonstrate that the ZnFe2O4 NPs endow an excellent antibacterial efficiency with a maximum zone of inhibition i.e.16 mm. The reactive oxygen species (ROS)-induced bacterial damage is caused by the ZnFe2O4 NPs. Subsequently, intracellular cytoplasmic leakage of sugar and protein confirms their ability to disturb the membrane integrity of bacteria. This study also demonstrates the prominent efficiency of ZnFe2O4 NPs in an anti-biofilm study by inhibiting biofilm formation up to 81.76% and reducing mature biofilm up to 56.22% at 75 μg/mL the minimum inhibitory concentration value. Therapeutic possibilities of the ZnFe2O4 NPs in antimicrobial applications are discussed which are helpful to overcome the challenges associated with biofilm infectivity.
650    _2
$a antibakteriální látky $x farmakologie $x terapeutické užití $7 D000900
650    12
$a antiinfekční látky $x farmakologie $7 D000890
650    _2
$a Bacteria $x metabolismus $7 D001419
650    _2
$a biofilmy $7 D018441
650    _2
$a železité sloučeniny $7 D005290
650    _2
$a Klebsiella pneumoniae $7 D007711
650    _2
$a mikrobiální testy citlivosti $7 D008826
650    12
$a nanočástice $7 D053758
650    _2
$a reaktivní formy kyslíku $x metabolismus $7 D017382
650    _2
$a cukry $x farmakologie $7 D000073893
650    _2
$a zinek $x farmakologie $7 D015032
655    _2
$a časopisecké články $7 D016428
700    1_
$a Raut, Siddheshwar D $u School of Physical Sciences, Swami Ramanand Teerth Marathwada University, Nanded, M.S, India
700    1_
$a Jadhav, Vijaykumar V $u Department of Physics, Shivaji College, Udgir, Dist. Latur, M.S, India $u Technion-Israel Institute of Technology, Haifa, Israel $u Materials Science and Engineering, Guangdong Technion-Israel Institute of Technology, Shantou, China
700    1_
$a Mulani, Ramjan M $u School of Life Sciences, Swami Ramanand Teerth Marathwada University, Nanded, M.S, India
700    1_
$a Kadam, Ambadas S $u Department of Botany, DSM'S ACS, College, Jintur, Dist, Parbhani, M.S, India. drambadaskadam@gmail.com
700    1_
$a Mane, Rajaram S $u School of Physical Sciences, Swami Ramanand Teerth Marathwada University, Nanded, M.S, India. rajarammane70@srtmun.ac.in
773    0_
$w MED00011005 $t Folia microbiologica $x 1874-9356 $g Roč. 67, č. 5 (2022), s. 747-755
856    41
$u https://pubmed.ncbi.nlm.nih.gov/35467317 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y - $z 0
990    __
$a 20221007 $b ABA008
991    __
$a 20240416152936 $b ABA008
999    __
$a ok $b bmc $g 1845901 $s 1174214
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2022 $b 67 $c 5 $d 747-755 $e 20220425 $i 1874-9356 $m Folia microbiologica $n Folia microbiol. (Prague) $x MED00011005
LZP    __
$a Pubmed-20221007

Najít záznam

Citační ukazatele

Možnosti archivace