-
Je něco špatně v tomto záznamu ?
Does Endoscopic Transnasal Optic Nerve Decompression Followed by Radiosurgery Improve Outcomes in the Treatment of Parasellar Meningiomas
P. Matoušek, J. Cvek, L. Čábalová, E. Misiorzová, O. Krejčí, R. Lipina, T. Krejčí
Jazyk angličtina Země Švýcarsko
Typ dokumentu časopisecké články, multicentrická studie
PubMed Central od 2018
Europe PubMed Central od 2018
ProQuest Central od 2018-01-01
Open Access Digital Library od 2014-01-01
Health & Medicine (ProQuest) od 2018-01-01
ROAD: Directory of Open Access Scholarly Resources od 2007
Odkazy
PubMed
36013604
DOI
10.3390/medicina58081137
Knihovny.cz E-zdroje
- MeSH
- dekomprese MeSH
- lidé MeSH
- meningeální nádory * komplikace radioterapie chirurgie MeSH
- meningeom * komplikace radioterapie chirurgie MeSH
- nádory baze lební * komplikace patologie chirurgie MeSH
- nervus opticus chirurgie MeSH
- prospektivní studie MeSH
- radiochirurgie * škodlivé účinky metody MeSH
- retrospektivní studie MeSH
- výsledek terapie MeSH
- Check Tag
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- multicentrická studie MeSH
INTRODUCTION: The clinical management of parasellar meningiomas (PM) is challenging due to their intimate association with critical neurovascular structures. Consensus regarding the recommended treatment protocol is lacking. This study will evaluate patients' visual outcomes following endoscopic transnasal optic nerve decompression (ETOND) and will investigate the possibility of reducing the rate of complications associated with stereotactic radiosurgery (SRS). METHODS: Retrospective analysis was conducted on all patients who underwent ETOND for PM between 2013 and 2020. The study comprised 12 patients (7 women and 5 men aged 36-75 years; mean, 55.2 years; median, 57.6 years) in which 14 optic nerve decompression procedures were carried out. Patients were followed up for 6 to 86 months (mean, 29.3 months; median, 25 months). There were five cases of spheno-orbital meningioma, four cases of cavernous sinus meningioma, and one case each of petro-clival meningioma, optic nerve sheath meningioma, and planum sphenoidale/tuberculum sellae meningioma. Visual outcome was evaluated and any postoperative complications noted. RESULTS: Improvements in visual acuity were noted in 10 of 14 eyes (71.4%) 3 to 6 months postoperation. Visual acuity remained stable in the remaining four eyes. No deterioration of visual acuity was noted during the follow-up period. In total, 9 of the 12 patients underwent SRS. No tumor growth was determined, while reduction in tumor volume was noted in five patients following SRS. No complications associated with SRS or the surgical procedure were noted. CONCLUSIONS: ETOND appears to be a promising technique for increasing rates of improved visual function, while reducing the risk of post SRS-related complications. In combination with subsequent SRS, it is an ideal treatment modality in the management of parasellar meningiomas. Confirmation of our findings would require a larger, prospective multicenter study.
Department of Neurosurgery University Hospital Ostrava 70852 Ostrava Czech Republic
Department of Oncology University Hospital Ostrava 70852 Ostrava Czech Republic
Faculty of Medicine University of Ostrava 70300 Ostrava Czech Republic
- 000
- 00000naa a2200000 a 4500
- 001
- bmc22024762
- 003
- CZ-PrNML
- 005
- 20221031100628.0
- 007
- ta
- 008
- 221017s2022 sz f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.3390/medicina58081137 $2 doi
- 035 __
- $a (PubMed)36013604
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a sz
- 100 1_
- $a Matoušek, Petr $u Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Ostrava, 70852 Ostrava, Czech Republic $u Faculty of Medicine, University of Ostrava, 70300 Ostrava, Czech Republic $1 https://orcid.org/0000000209306773
- 245 10
- $a Does Endoscopic Transnasal Optic Nerve Decompression Followed by Radiosurgery Improve Outcomes in the Treatment of Parasellar Meningiomas / $c P. Matoušek, J. Cvek, L. Čábalová, E. Misiorzová, O. Krejčí, R. Lipina, T. Krejčí
- 520 9_
- $a INTRODUCTION: The clinical management of parasellar meningiomas (PM) is challenging due to their intimate association with critical neurovascular structures. Consensus regarding the recommended treatment protocol is lacking. This study will evaluate patients' visual outcomes following endoscopic transnasal optic nerve decompression (ETOND) and will investigate the possibility of reducing the rate of complications associated with stereotactic radiosurgery (SRS). METHODS: Retrospective analysis was conducted on all patients who underwent ETOND for PM between 2013 and 2020. The study comprised 12 patients (7 women and 5 men aged 36-75 years; mean, 55.2 years; median, 57.6 years) in which 14 optic nerve decompression procedures were carried out. Patients were followed up for 6 to 86 months (mean, 29.3 months; median, 25 months). There were five cases of spheno-orbital meningioma, four cases of cavernous sinus meningioma, and one case each of petro-clival meningioma, optic nerve sheath meningioma, and planum sphenoidale/tuberculum sellae meningioma. Visual outcome was evaluated and any postoperative complications noted. RESULTS: Improvements in visual acuity were noted in 10 of 14 eyes (71.4%) 3 to 6 months postoperation. Visual acuity remained stable in the remaining four eyes. No deterioration of visual acuity was noted during the follow-up period. In total, 9 of the 12 patients underwent SRS. No tumor growth was determined, while reduction in tumor volume was noted in five patients following SRS. No complications associated with SRS or the surgical procedure were noted. CONCLUSIONS: ETOND appears to be a promising technique for increasing rates of improved visual function, while reducing the risk of post SRS-related complications. In combination with subsequent SRS, it is an ideal treatment modality in the management of parasellar meningiomas. Confirmation of our findings would require a larger, prospective multicenter study.
- 650 _2
- $a dekomprese $7 D003664
- 650 _2
- $a ženské pohlaví $7 D005260
- 650 _2
- $a lidé $7 D006801
- 650 _2
- $a mužské pohlaví $7 D008297
- 650 12
- $a meningeální nádory $x komplikace $x radioterapie $x chirurgie $7 D008577
- 650 12
- $a meningeom $x komplikace $x radioterapie $x chirurgie $7 D008579
- 650 _2
- $a nervus opticus $x chirurgie $7 D009900
- 650 _2
- $a prospektivní studie $7 D011446
- 650 12
- $a radiochirurgie $x škodlivé účinky $x metody $7 D016634
- 650 _2
- $a retrospektivní studie $7 D012189
- 650 12
- $a nádory baze lební $x komplikace $x patologie $x chirurgie $7 D019292
- 650 _2
- $a výsledek terapie $7 D016896
- 655 _2
- $a časopisecké články $7 D016428
- 655 _2
- $a multicentrická studie $7 D016448
- 700 1_
- $a Cvek, Jakub $u Faculty of Medicine, University of Ostrava, 70300 Ostrava, Czech Republic $u Department of Oncology, University Hospital Ostrava, 70852 Ostrava, Czech Republic
- 700 1_
- $a Čábalová, Lenka $u Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Ostrava, 70852 Ostrava, Czech Republic $u Faculty of Medicine, University of Ostrava, 70300 Ostrava, Czech Republic $1 https://orcid.org/000000022117040X
- 700 1_
- $a Misiorzová, Eva $u Faculty of Medicine, University of Ostrava, 70300 Ostrava, Czech Republic $u Department of Neurosurgery, University Hospital Ostrava, 70852 Ostrava, Czech Republic
- 700 1_
- $a Krejčí, Ondřej $u Department of Neurosurgery, University Hospital Ostrava, 70852 Ostrava, Czech Republic
- 700 1_
- $a Lipina, Radim $u Faculty of Medicine, University of Ostrava, 70300 Ostrava, Czech Republic $u Department of Neurosurgery, University Hospital Ostrava, 70852 Ostrava, Czech Republic
- 700 1_
- $a Krejčí, Tomáš $u Faculty of Medicine, University of Ostrava, 70300 Ostrava, Czech Republic $u Department of Neurosurgery, University Hospital Ostrava, 70852 Ostrava, Czech Republic $1 https://orcid.org/0000000169962679
- 773 0_
- $w MED00180386 $t Medicina $x 1648-9144 $g Roč. 58, č. 8 (2022)
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/36013604 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y p $z 0
- 990 __
- $a 20221017 $b ABA008
- 991 __
- $a 20221031100625 $b ABA008
- 999 __
- $a ok $b bmc $g 1854480 $s 1176052
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2022 $b 58 $c 8 $e 20220822 $i 1648-9144 $m Medicina $n Medicina (Kaunas) $x MED00180386
- LZP __
- $a Pubmed-20221017