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PDBe and PDBe-KB: Providing high-quality, up-to-date and integrated resources of macromolecular structures to support basic and applied research and education

M. Varadi, S. Anyango, SD. Appasamy, D. Armstrong, M. Bage, J. Berrisford, P. Choudhary, D. Bertoni, M. Deshpande, GD. Leines, J. Ellaway, G. Evans, R. Gaborova, D. Gupta, A. Gutmanas, D. Harrus, GJ. Kleywegt, WM. Bueno, N. Nadzirin, S. Nair, L....

. 2022 ; 31 (10) : e4439. [pub] -

Language English Country United States

Document type Journal Article, Research Support, Non-U.S. Gov't

Grant support
BB/R015201/1 Biotechnology and Biological Sciences Research Council - United Kingdom
223739/Z/21/Z Wellcome Trust - United Kingdom
BB/V004247/1 Biotechnology and Biological Sciences Research Council - United Kingdom
BB/V016113/1 Biotechnology and Biological Sciences Research Council - United Kingdom
BB/S017135/1 Biotechnology and Biological Sciences Research Council - United Kingdom
221327/Z/20/Z Wellcome Trust - United Kingdom
BB/T01959X/1 Biotechnology and Biological Sciences Research Council - United Kingdom
BB/P025846/1 Biotechnology and Biological Sciences Research Council - United Kingdom
BB/M011674/1 Biotechnology and Biological Sciences Research Council - United Kingdom
BB/P024351/1 Biotechnology and Biological Sciences Research Council - United Kingdom
104948/Z/14/Z Wellcome Trust - United Kingdom
218303/Z/19/Z Wellcome Trust - United Kingdom
BB/W017970/1 Biotechnology and Biological Sciences Research Council - United Kingdom
BB/V018779/1 Biotechnology and Biological Sciences Research Council - United Kingdom
BB/S020071/1 Biotechnology and Biological Sciences Research Council - United Kingdom
Wellcome Trust - United Kingdom

E-resources Online Full text

NLK Free Medical Journals from 1992 to 1 year ago
PubMed Central from 1992 to 1 year ago
Europe PubMed Central from 1992 to 1 year ago
Medline Complete (EBSCOhost) from 2010-01-01 to 1 year ago
Wiley Free Content from 1996 to 1 year ago

The archiving and dissemination of protein and nucleic acid structures as well as their structural, functional and biophysical annotations is an essential task that enables the broader scientific community to conduct impactful research in multiple fields of the life sciences. The Protein Data Bank in Europe (PDBe; pdbe.org) team develops and maintains several databases and web services to address this fundamental need. From data archiving as a member of the Worldwide PDB consortium (wwPDB; wwpdb.org), to the PDBe Knowledge Base (PDBe-KB; pdbekb.org), we provide data, data-access mechanisms, and visualizations that facilitate basic and applied research and education across the life sciences. Here, we provide an overview of the structural data and annotations that we integrate and make freely available. We describe the web services and data visualization tools we offer, and provide information on how to effectively use or even further develop them. Finally, we discuss the direction of our data services, and how we aim to tackle new challenges that arise from the recent, unprecedented advances in the field of structure determination and protein structure modeling.

References provided by Crossref.org

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