-
Something wrong with this record ?
PDBe and PDBe-KB: Providing high-quality, up-to-date and integrated resources of macromolecular structures to support basic and applied research and education
M. Varadi, S. Anyango, SD. Appasamy, D. Armstrong, M. Bage, J. Berrisford, P. Choudhary, D. Bertoni, M. Deshpande, GD. Leines, J. Ellaway, G. Evans, R. Gaborova, D. Gupta, A. Gutmanas, D. Harrus, GJ. Kleywegt, WM. Bueno, N. Nadzirin, S. Nair, L....
Language English Country United States
Document type Journal Article, Research Support, Non-U.S. Gov't
Grant support
BB/R015201/1
Biotechnology and Biological Sciences Research Council - United Kingdom
223739/Z/21/Z
Wellcome Trust - United Kingdom
BB/V004247/1
Biotechnology and Biological Sciences Research Council - United Kingdom
BB/V016113/1
Biotechnology and Biological Sciences Research Council - United Kingdom
BB/S017135/1
Biotechnology and Biological Sciences Research Council - United Kingdom
221327/Z/20/Z
Wellcome Trust - United Kingdom
BB/T01959X/1
Biotechnology and Biological Sciences Research Council - United Kingdom
BB/P025846/1
Biotechnology and Biological Sciences Research Council - United Kingdom
BB/M011674/1
Biotechnology and Biological Sciences Research Council - United Kingdom
BB/P024351/1
Biotechnology and Biological Sciences Research Council - United Kingdom
104948/Z/14/Z
Wellcome Trust - United Kingdom
218303/Z/19/Z
Wellcome Trust - United Kingdom
BB/W017970/1
Biotechnology and Biological Sciences Research Council - United Kingdom
BB/V018779/1
Biotechnology and Biological Sciences Research Council - United Kingdom
BB/S020071/1
Biotechnology and Biological Sciences Research Council - United Kingdom
Wellcome Trust - United Kingdom
NLK
Free Medical Journals
from 1992 to 1 year ago
PubMed Central
from 1992 to 1 year ago
Europe PubMed Central
from 1992 to 1 year ago
Medline Complete (EBSCOhost)
from 2010-01-01 to 1 year ago
Wiley Free Content
from 1996 to 1 year ago
PubMed
36173162
DOI
10.1002/pro.4439
Knihovny.cz E-resources
- MeSH
- Databases, Protein MeSH
- Protein Conformation MeSH
- Nucleic Acids * MeSH
- Proteins * chemistry MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Geographicals
- Europe MeSH
The archiving and dissemination of protein and nucleic acid structures as well as their structural, functional and biophysical annotations is an essential task that enables the broader scientific community to conduct impactful research in multiple fields of the life sciences. The Protein Data Bank in Europe (PDBe; pdbe.org) team develops and maintains several databases and web services to address this fundamental need. From data archiving as a member of the Worldwide PDB consortium (wwPDB; wwpdb.org), to the PDBe Knowledge Base (PDBe-KB; pdbekb.org), we provide data, data-access mechanisms, and visualizations that facilitate basic and applied research and education across the life sciences. Here, we provide an overview of the structural data and annotations that we integrate and make freely available. We describe the web services and data visualization tools we offer, and provide information on how to effectively use or even further develop them. Finally, we discuss the direction of our data services, and how we aim to tackle new challenges that arise from the recent, unprecedented advances in the field of structure determination and protein structure modeling.
CEITEC Central European Institute of Technology Masaryk University Brno Czech Republic
European Molecular Biology Laboratory European Bioinformatics Institute Hinxton
National Centre for Biomolecular Research Faculty of Science Masaryk University Brno Czech Republic
References provided by Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc22033156
- 003
- CZ-PrNML
- 005
- 20230131150927.0
- 007
- ta
- 008
- 230120s2022 xxu f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.1002/pro.4439 $2 doi
- 035 __
- $a (PubMed)36173162
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a xxu
- 100 1_
- $a Varadi, Mihaly $u European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton $1 https://orcid.org/0000000236870839
- 245 10
- $a PDBe and PDBe-KB: Providing high-quality, up-to-date and integrated resources of macromolecular structures to support basic and applied research and education / $c M. Varadi, S. Anyango, SD. Appasamy, D. Armstrong, M. Bage, J. Berrisford, P. Choudhary, D. Bertoni, M. Deshpande, GD. Leines, J. Ellaway, G. Evans, R. Gaborova, D. Gupta, A. Gutmanas, D. Harrus, GJ. Kleywegt, WM. Bueno, N. Nadzirin, S. Nair, L. Pravda, MQL. Afonso, D. Sehnal, A. Tanweer, J. Tolchard, C. Abrams, R. Dunlop, S. Velankar
- 520 9_
- $a The archiving and dissemination of protein and nucleic acid structures as well as their structural, functional and biophysical annotations is an essential task that enables the broader scientific community to conduct impactful research in multiple fields of the life sciences. The Protein Data Bank in Europe (PDBe; pdbe.org) team develops and maintains several databases and web services to address this fundamental need. From data archiving as a member of the Worldwide PDB consortium (wwPDB; wwpdb.org), to the PDBe Knowledge Base (PDBe-KB; pdbekb.org), we provide data, data-access mechanisms, and visualizations that facilitate basic and applied research and education across the life sciences. Here, we provide an overview of the structural data and annotations that we integrate and make freely available. We describe the web services and data visualization tools we offer, and provide information on how to effectively use or even further develop them. Finally, we discuss the direction of our data services, and how we aim to tackle new challenges that arise from the recent, unprecedented advances in the field of structure determination and protein structure modeling.
- 650 _2
- $a databáze proteinů $7 D030562
- 650 12
- $a nukleové kyseliny $7 D009696
- 650 _2
- $a konformace proteinů $7 D011487
- 650 12
- $a proteiny $x chemie $7 D011506
- 651 _2
- $a Evropa $7 D005060
- 655 _2
- $a časopisecké články $7 D016428
- 655 _2
- $a práce podpořená grantem $7 D013485
- 700 1_
- $a Anyango, Stephen $u European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton
- 700 1_
- $a Appasamy, Sri Devan $u European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton
- 700 1_
- $a Armstrong, David $u European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton
- 700 1_
- $a Bage, Marcus $u European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton
- 700 1_
- $a Berrisford, John $u European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton
- 700 1_
- $a Choudhary, Preeti $u European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton
- 700 1_
- $a Bertoni, Damian $u European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton
- 700 1_
- $a Deshpande, Mandar $u European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton
- 700 1_
- $a Leines, Grisell Diaz $u European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton
- 700 1_
- $a Ellaway, Joseph $u European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton
- 700 1_
- $a Evans, Genevieve $u European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton
- 700 1_
- $a Gaborova, Romana $u European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton
- 700 1_
- $a Gupta, Deepti $u European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton
- 700 1_
- $a Gutmanas, Aleksandras $u European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton
- 700 1_
- $a Harrus, Deborah $u European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton
- 700 1_
- $a Kleywegt, Gerard J $u European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton
- 700 1_
- $a Bueno, Weslley Morellato $u European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton
- 700 1_
- $a Nadzirin, Nurul $u European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton
- 700 1_
- $a Nair, Sreenath $u European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton
- 700 1_
- $a Pravda, Lukas $u European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton
- 700 1_
- $a Afonso, Marcelo Querino Lima $u European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton
- 700 1_
- $a Sehnal, David $u European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton $u CEITEC - Central European Institute of Technology, Masaryk University, Brno, Czech Republic $u National Centre for Biomolecular Research, Faculty of Science, Masaryk University, Brno, Czech Republic
- 700 1_
- $a Tanweer, Ahsan $u European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton
- 700 1_
- $a Tolchard, James $u European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton
- 700 1_
- $a Abrams, Charlotte $u European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton
- 700 1_
- $a Dunlop, Roisin $u European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton
- 700 1_
- $a Velankar, Sameer $u European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton
- 773 0_
- $w MED00008270 $t Protein science : a publication of the Protein Society $x 1469-896X $g Roč. 31, č. 10 (2022), s. e4439
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/36173162 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y p $z 0
- 990 __
- $a 20230120 $b ABA008
- 991 __
- $a 20230131150923 $b ABA008
- 999 __
- $a ok $b bmc $g 1891740 $s 1184491
- BAS __
- $a 3
- BAS __
- $a PreBMC-MEDLINE
- BMC __
- $a 2022 $b 31 $c 10 $d e4439 $e - $i 1469-896X $m Protein science $n Protein Sci $x MED00008270
- GRA __
- $a BB/R015201/1 $p Biotechnology and Biological Sciences Research Council $2 United Kingdom
- GRA __
- $a 223739/Z/21/Z $p Wellcome Trust $2 United Kingdom
- GRA __
- $a BB/V004247/1 $p Biotechnology and Biological Sciences Research Council $2 United Kingdom
- GRA __
- $a BB/V016113/1 $p Biotechnology and Biological Sciences Research Council $2 United Kingdom
- GRA __
- $a BB/S017135/1 $p Biotechnology and Biological Sciences Research Council $2 United Kingdom
- GRA __
- $a 221327/Z/20/Z $p Wellcome Trust $2 United Kingdom
- GRA __
- $a BB/T01959X/1 $p Biotechnology and Biological Sciences Research Council $2 United Kingdom
- GRA __
- $a BB/P025846/1 $p Biotechnology and Biological Sciences Research Council $2 United Kingdom
- GRA __
- $a BB/M011674/1 $p Biotechnology and Biological Sciences Research Council $2 United Kingdom
- GRA __
- $a BB/P024351/1 $p Biotechnology and Biological Sciences Research Council $2 United Kingdom
- GRA __
- $a 104948/Z/14/Z $p Wellcome Trust $2 United Kingdom
- GRA __
- $a 218303/Z/19/Z $p Wellcome Trust $2 United Kingdom
- GRA __
- $a BB/W017970/1 $p Biotechnology and Biological Sciences Research Council $2 United Kingdom
- GRA __
- $a BB/V018779/1 $p Biotechnology and Biological Sciences Research Council $2 United Kingdom
- GRA __
- $a BB/S020071/1 $p Biotechnology and Biological Sciences Research Council $2 United Kingdom
- GRA __
- $p Wellcome Trust $2 United Kingdom
- LZP __
- $a Pubmed-20230120